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All published articles 883

Anticonvulsant and Antidepressant Effects of Daniellia oliveri (Rolfe) Hutch and Dalz Aqueous Extract in Pilocarpine Model of Temporal Lobe Epilepsy in Mice

Jean-Jacques Kodji Midala, Njapdounke Kameni Jacqueline Stéphanie, Ngo Ngimout Kidjama, Joseph Ngaibi, Wangbara alkali tchang, Bigued, Lamare Tchachoua Adrien, Vanessa Tita Jugha, Germain Sotoing Taiwe & Ngo Bum Elisabeth · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

In temporal lobe epilepsy, an average of 30% suffer from depression.The objective of this study is to evaluate the anticonvulsant and antidepressant effects of Daniellia oliveri in pilocarpine model of temporal lobe epilepsy. the experiment lasted 7 days.Muss musculus Swiss mice...

Open access Research Article 10.9734/jamps/2025/v27i4773

The Phytochemical Profile of Sansevieria Roxburghiana: A Key to Unlocking Its Therapeutic Applications

Madhavi Pillalamarri, Snehalatha Vaddemani, Mahathi Pasumarti, Tharun Madhurna, Devaki Pasupula & Siddhartha Lolla · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aim: This study examines the potential of plant analgesics as an analgesic measure concerning their safety, efficacy and affordability over conventional synthetic analgesics. Study Design: This is a review article addressing the classification of pain, the action of analgesic mec...

Open access Research Article 10.9734/jamps/2025/v27i5774

Anticonvulsant and Anti-amnesic Effects of an Aqueous Extract of Crassocephalum bauchiense (Hutch.) Milne-Redh. (Asteraceae) in Mice Pilocarpine Model of Temporal Lobe Epilepsy

Tchang Alkali Wangbara, Jacqueline Stephanie Kameni Njapdounke, Ngo Ngimout Kidjama, Bigued, Jean-Jacques Kodji Midala, Joseph Ngaibi, Lamare Tchachoua Adrien, Vanessa Tita Jugha, Germain Sotoing Taiwe & Elisabeth Ngo Bum · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

This study aimed to investigate the anticonvulsant and anti-amnesic effects of Crassocephalum bauchiense aqueous extract in pilocarpine model of temporal lobe epilepsy. Mice were treated for seven consecutive days as follows: one normal group and one negative control group that r...

Open access Research Article 10.9734/jamps/2025/v27i4771

Assessing the Feasibility and Sustainability of a 100% Drug Prescription-fill Policy at the University of Benin Teaching Hospital, Nigeria: Implications for National Health and Drug Policies

Okuoimose Jacob Egharevba, Abdulrauf Ambali, S.E Aghahowa & Thaddeus Aichienede · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: To determine the feasibility and sustainability of the 100% drug prescription-fill policy goals and compare its achievements with the alternate policy in fulfilling the national Health policies. Study Design: The study was limited to staff who are five years and above in th...

Open access Research Article 10.9734/jamps/2025/v27i4770

Ethical and Regulatory Challenges for Contract Research Organizations Conducting (Outsourced) Clinical Research in Sub-Saharan Africa with a Case Study of Cameroon

Charles Ntungwen Fokunang, Estella Achick Tembe-Fokunang, Marceline Djuidje Ngounou, Basile Ngono, Innocente Mantsana, Pasteur Sap Jacques Duclaire, Mgr Etoundi Jean, Mpah Wanga Julien Eymard, Mfochive Njindam Illiasou, Christie Tiwoda, Francis Ndongo Ateba, Tchinda Tiabou, Lowe Gnintedem Patrick, Eboumbou Moukoko Caroline Else, Ngu Paul Nembo, Jerome Ateudjio, Charles Kouanfack, Leopold Lehman, Binan Fidele Ange, Marie Claire Assoumou Okomo, Mbacham Fon Wilfred & Vincent Pryde Kehdingha Titanji · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: Contract Research Organizations (CROs), Clinical Research Centers/Networks and private research institutions play an important role in the clinical research process, especially in the drug discovery and development process. They act as essential partners for pharmac...

Open access Research Article 10.9734/jamps/2025/v27i4768

Exercise Mediated Prevention of Cognitive Decline

Zain Jandial, Ashvin Kumar & Greg Whyte · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Decline in cognitive functions and behavioural problems are the common and inter-related symptoms of dementia. Progression of behavioural problems in people with dementia is associated with a higher rate of cognitive decline. Cognitive and behavioural problems can induce diverse...

Open access Research Article 10.9734/jamps/2025/v27i4769

Effects of Melatonin on Level of Cytokine in Patients with AIDS

F.R. Nerone, F.N. Ferraz, P.F.B. Mendonça, M. Spack Jr & A. R. T. Pupulin · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: Changes in cytokine levels in HIV infected individuals can affect the function of the immune system and have the potential to directly impact the course of HIV disease by enhancing or suppressing HIV replication. Melatonin influences various immune cells, including lymphocy...

Open access Research Article 10.9734/jamps/2025/v27i4767

Phytochemical Screening and Blood Glucose-lowering Effects of Ethanol Leaf Extract of Two Corchorus Species on Alloxan-induced Diabetic Albino Rats

Frank Uchenna Eneh, Uchechukwu Chibuzo Ogbodo, Chinwe Nonyelum Ezekwesili, Chidozie Godwin Ugochukwu, Chibueze Onwuegbusi & Akudo Ruth Aguedosi · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Diabetes mellitus is a metabolic disorder with tremendous debilitating effects of high public health impact. Drugs employed in the treatment and management of the condition have remained unsuccessful in curbing the effects of the disease necessitating a turn to natura...

Open access Research Article 10.9734/jamps/2025/v27i4766

The Role of Workload and Job Specification in Needle Stick Injuries among Health Care Practitioners in Tertiary Hospitals, Rivers State, Nigeria

Amadi, Christian Emeka & Otokunefor, Ochuko · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Needle stick injuries have been a major preventable hazard among hospital staff for centuries. With a prevalence ranging from 37-95% among various sets of healthcare workers. It has also resulted in health care workers acquiring some viral infections over time. This c...

Open access Research Article 10.9734/jamps/2025/v27i4765

Assessment of Knowledge, Attitudes and Practices of Emergency Contraceptive Methods among Female Students of the University of Dschang, Cameroon

DJAM CHEFOR ALAIN, EARNEST NJIH TABAH, Kepgang Evrard, Gabriel Tchatchouang Mabou, Ngam Lois Nabuin, Augustine Eyong Bate, Moati Angwah Russell, Akwe Nzume Blaise & Libah Junior Dinkah · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Unintended pregnancy is a major public health problem and emergency contraceptives can be an effective way of fighting against them. 75% of unintended pregnancies occur in adolescents. University students are in the sexually active age group and are at higher risks of...

Open access Research Article 10.9734/jamps/2025/v27i4764

Identification, Molecular Docking and Pharmacokinetic Evaluation of Bioactive Flavonoids from Dennettia tripetala Baker. f. (Annonaceae) Root

Enema, Onojah John, Umoh, Uwemedimo Francis, Ekarika, C. Johnson, Khalid, Doudin & Johnny, I. Imoh · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Dennettia tripetala Baker f. (Annonaceae) is a medicinal plant traditionally used for treating ailments such as pain, inflammation, diabetes, and respiratory conditions. This study focused on isolating and characterizing bioactive compounds from the ethyl acetate fraction of D. t...

Open access Research Article 10.9734/jamps/2025/v27i4763

Assessment of Factors Influencing Tardiness and Poor-Compliance with ANC at Mwembeladu Hospital in Zanzibar, 2024

Rodolfo Isidro Bosch Bayard, Chukwuma J. Okafor, Diane Millo Martin, Nibras M. Hilal, Tarik A. Khamis, Asila M. Haji, Rayyan J. Ali, Angel Badia Saiz & Emmanuel Ifeanyi Obeagu · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Antenatal care (ANC) is vital for maternal and infant health, yet women in Zanzibar frequently delay their first ANC visit and struggle with adherence to visits to ANC. This study investigates the socio-demographic factors contributing to these delays. It will describ...

Open access Research Article 10.9734/jamps/2025/v27i3762

Tamarillo Extract Cream Mitigates UVB-Induced Hyperpigmentation in Guinea Pigs

Sumarjaya, N.P.E.P, Sugiritama, I.W, Muliarta, I.M, Yasa, I.W.P.S, Hendrayana, M.A & Ernawati, D.K · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: To evaluate the effect of tamarillo fruit ethanol extract cream on the levels of malondialdehyde (MDA), tyrosinase enzyme, and melanin in the skin of male guinea pigs (Cavia porcellus) exposed to ultraviolet B (UVB) radiation. Study Design: Randomized post-test only control...

Open access Research Article 10.9734/jamps/2025/v27i3761

Assessment of the Level of Direct Health Facility Funding Awareness and Training among Staff of Primary Health Care Facilities in Plateau State

Christopher Bewa · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

The study carried out an assessment of the level of direct health facility funding awareness and training among staff of primary health care facilities in Plateau State. Pragmatism research philosophy and descriptive cross-sectional design were used. The population of the study c...

Open access Research Article 10.9734/jamps/2025/v27i3760

Phytochemical Profiling of Athimathura Chooranam a Polyherbal Formulation: A GC-MS Analysis

Rakshana, Shalini & Chitra · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: Athimathura Choornam, a traditional Siddha formulation, has been employed for centuries to treat various ailments. Aim: This study is aimed to investigate the phytochemical profile of Athimathura Choornam by using Gas Chromatography-Mass Spectrometry (GC-MS) analysi...

Open access Research Article 10.9734/jamps/2025/v27i3759