Alzheimer’s disease is an insidious disease of the brain. It is a degenerative and intractable neurological disorder that causes deterioration of memory, judgment, and reasoning in the elderly. About 46.8 million people worldwide are suffering from AD; prevalence is expected to a...
Open access
Research Article10.9734/JAMPS/2016/28271
Aim: To develop a novel, simple, precise and rapid HPTLC protocol for the analysis of marrubiin (a furan labdane diterpene) in herbal extracts and formulations. Methodology: The marrubiin can be quantified by performing the HPTLC on silica gel F254 plates using toluene: ethyl ace...
Open access
Research Article10.9734/JAMPS/2016/29840
Aim: The nutraceutic effect of millet-garlic blend against trypanosomiasis in Trypanosoma brucei brucei challenged rats was investigated in this study. Experimental Design: The experimental rats were grouped into A, B, C, D, E, F, G, H, I, and J in a complete randomised clinical...
Open access
Research Article10.9734/JAMPS/2016/26318
Aims: The study was aimed to investigate the efficacy of Telfairia occidentalis (T. occidentalis) extracts in the attenuation of CCl4-mediated oxidative stress. Place and Duration of Study: Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomosho, Nigeria,...
Open access
Research Article10.9734/JAMPS/2016/29199
Background: Chronic allergic lung diseases, such as allergic asthma, are often marked by increased systemic inflammatory responses and cachexia co-morbidities. Objectives: The study aimed at evaluating the systemic anti-inflammatory and anti-cachectic properties of a hydro-ethano...
Open access
Research Article10.9734/JAMPS/2016/29032
Aims: Oxytocin (OT) hormone has been recently recognized as a cardiovascular hormone with diverse regulatory roles. The present study examined the potential protective effect of exogenous OT administration on hypercholesterolemia-induced injury in rat heart and possible mechanism...
Open access
Research Article10.9734/JAMPS/2016/28932
Introduction: Cervical cancer is the fourth most common cancer affecting women in the world, 527,000 new cases were reported and over 250,000 deaths were reported each year. The major risk factor of cervical cancer is infection with HPV. The aim of our research is to determine th...
Open access
Research Article10.9734/JAMPS/2016/29034
Rational prescribing is vital to achieving rational drug use but limited studies exist on the prescription practices, causes, and types of prescription error in developing countries. Prescription error is one of the leading causes of morbidity and mortality globally. However, due...
Open access
Research Article10.9734/JAMPS/2016/26864
Baclofen is a centrally acting antispasmodic agent that is commonly prescribed to patients suffering from spinal cord problems. Nearly 85% of baclofen is excreted by the kidneys whereas the remaining 15% is metabolized by the liver. In patients with renal insufficiency, baclofen...
Open access
Research Article10.9734/JAMPS/2016/29261
Objectives: To evaluate the in vitro mutual interaction of ketorolac tromethamine with bovine serum albumin (BSA) using fluorescence spectroscopy under different conditions. Materials and Methods: Different concentrations of ketorolac were mixed with 20 µM bovine serum albumin so...
Open access
Research Article10.9734/JAMPS/2016/29006
Epilepsy is a chronic neurological disorder manifested as unpredictable, unprovoked recurrent seizures that affect a variety of mental and physical functions. Despite the use of current anti-epileptic drugs (AEDs) about 30% of patients remain refractory, while 30-40% have associa...
Open access
Research Article10.9734/JAMPS/2016/24441
Background: Many strategies have been employed to improve compliances to antihypertensive medications but these efforts are not translated into good compliances with several patients leading to high cases of morbidity and mortality. The study probes into the medication compliance...
Open access
Research Article10.9734/JAMPS/2016/28484
Helicobacter pylori is a bacterium that is widespread in the world's population and constitutes a risk factor for the development of gastric cancer. One possible cause of treatment failure is antimicrobial resistance, indicating the importance of susceptibility testing. Aims: The...
Open access
Research Article10.9734/JAMPS/2016/28658
Aim: Day case laparoscopic cholecystectomy is achievable but in most hospitals it is not routine. We describe our experience with day case laparoscopic cholecystectomy in a rural Queensland hospital. Methods: Retrospective analysis of consecutive adult patients with uncomplicated...
Open access
Research Article10.9734/JAMPS/2016/29117
Corn silk is thought to possess medicinal properties according to Nigerian folklore. This study was undertaken to appraise its phytochemical constituents and anti-microbial activities. Data obtained revealed that alkaloids, flavonoids, tannins, saponins, steroids, glycosides and...
Open access
Research Article10.9734/JAMPS/2016/28530