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All published articles 883

In vitro Antimitotic Activity and Molecular Docking Studies of Isolated Compounds from Rhynchosia beddomei

M. Lakshmi Madhuri & R. Raja Reddy · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

The goal of this work was to use an exquisite combination of phytopharmacological and modern computational tools to examine the anticancer potential of Rhynchosia beddomei. The methanolic extract of Rhynchosia beddomei was screened for in vitro antimitotic activity like Allium ce...

Open access Research Article 10.9734/jamps/2022/v24i430297

COVID-19 and Obesity: The Collision of the Two Disasters

Roni Varghese Oommen, Shashank Gotarkar & Swarupa Chakole · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

The first instances of COVID-19 were reported in late December in Wuhan, Hubei region, China. This virus is most commonly seen in mammals, most notably bats, camels, cows, and some kinds of pigs. Despite this, it is well recognised that viral transfer from animals to humans is ex...

Open access Research Article 10.9734/jamps/2022/v24i530298

Effects of the Anti-diabetic Polyherbal (Ruzu Bitters) on Glucose, Hepatic and Renal Parameters in Alloxan-induced Diabetic Rats

Ojoye N. Briggs, Kemzi N. Elechi-Amadi, Tarila N. Aleruchi-Didia, Eberechukwu O. Anyalebechi & Shammah Agwor · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Aim: This study evaluated the effects of the anti-diabetic polyherbal (Ruzu Bitters) on glucose, hepatic and renal parameters in alloxan-induced diabetic rats. Methodology: A total of 35 male Albino rats weighing between 120-140 g were used for this study. Diabetes was induced by...

Open access Research Article 10.9734/jamps/2022/v24i430296

Curative and Toxic Effects of Selected Medicinal Plants on Internal Organs of Rattus albus Experimentally Infected with Human Intestinal Parasites

Immaculata O. Uduchi, Okolie Nnaemeka J. C., Ambrose U. Opara, Cajetan E. Ilo, Emmanuel Ifeanyi Obeagu & Samuel I. Ogenyi · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Curative and Toxic effects of selected plant extracts: (Napleonaea imperalis, Sida acuta and Vernonia amygdalina) on Rattus albus experimentally infected with human intestinal parasites was studied from October 2014 to March 2016. Two hundred and thirty (230) male and female pati...

Open access Research Article 10.9734/jamps/2022/v24i430295

Alteration of Some Sperm Proteins, Anti-oxidants, and Prostate-specific Antigen in the Seminal Plasma of Bacteriospermic Infertile Males

Aminayanate M. Aworu, Ibioku Elekima, Adline Ben-Chioma, Holy Brown & Ebirien-Agana S. Bartimaeus · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Aim: To investigate the alteration of some sperm proteins, anti-oxidants, and prostate-specific antigen in the seminal plasma of bacteriospermic infertile males. Study Design:  The study is a case-control design to investigate the semen parameters and some sperm proteins in infer...

Open access Research Article 10.9734/jamps/2022/v24i430294

Evaluation of Histopathological Effects of Smoked Marijuana on Albino Rats and Its Oxidative Stress Indices

Nnaemeka Okorie, Emmanuel Ifeanyi Obeagu, Mfon Ufot, Simon Onyema Azi, Ugonma Agwu Ude, Gideon Ama Ibiam, Christopher Okwu Ogbuanya, Innocent Chidi Jacob & Ewa Ibe Onyekachi · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Smoking marijuana (cannabis Savita), a psychoactive substance may result in side effect on living cells of the system and oxidative stress may meditate some of these effects. This study aims to evaluate the acute and chronic histopathological effect on wistar albino rat as well a...

Open access Research Article 10.9734/jamps/2022/v24i330293

Effective Inhibition of H5N1 Influenza Virus Infectivity using Safe and Calculated Low Power Generated from Life Restoration device under Different Conditions

Waleed Ezzat Madboly & Ahmed M. Abu-Dief · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Objectives: The use of the antiviral drugs and vaccination against pathogenic viruses induce some disorders and death cases. Therefore, it is urgent to develop an alternative therapy to protect and reduce the virus side effects. Here, in this report we designated a novel device t...

Open access Research Article 10.9734/jamps/2022/v24i330292

Acute and Sub-Acute Evaluations of Parsonsia straminea Stem Bark Ethanol Extract Impact on Some Behavioral Parameters in Mice

James Kemelayefa, Hope Kagbo & Udeme Georgewill · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Objectives: The plant Parsonsia straminea (P.S) have little or no ethnopharmacological records but local claims; as such its behavioral impact determination leads this study. The study team is poised at assessing the changes in behaviors such as: Motor coordination, anxiety, and...

Open access Research Article 10.9734/jamps/2022/v24i330291

Prevalence of Methicillin Resistant Staphylococcus aureus Infections among Hospitalized Wound Patients from Selected Tertiary Hospitals within Enugu Metropolis

Chidimma Maureen Chukwueze, Theophilus Kachi Udeani, Emmanuel Ifeanyi Obeagu, Justina Nwabunachi Ikpenwa & Asogwa Nneka · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

The incidence of Staphylococcus aureus infection especially in wound infections continues to rise. This study was aimed to evaluate the prevalence of methicillin resistant Staphylococcus aureus in hospitalized patients with wound infections in selected tertiary hospitals within E...

Open access Research Article 10.9734/jamps/2022/v24i330290

Acute and Sub-chronic Toxicological Studies of Citrus aurantium Fruit Juice in Wistar Rats

Obiajulu Christian Ezeigwe, Uchechukwu Chibuzo Ogbodo, Gift Nonso Okwuenu, Ezennaya Chidinma Felicia & Ifedilichukwu Nma Helen · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Citrus aurantium remains an excellent source of vitamins and phytochemicals. C. aurantium has been associated with lots of medicinal uses ranging from weight management to the treatment of nausea, cardiovascular diseases and cancer. This study therefore aimed at determining the a...

Open access Research Article 10.9734/jamps/2022/v24i330289

An Overview of FDA Approved Liposome Formulations for Cancer Therapy

Khushal Gajera & Adil Patel · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

One of the early achievements of researchers to develop Nano drug delivery systems were successfully manifested in the form of liposomes. Since the time of its invention in 1965, many technological advancements have been witnessed in Liposomal drug delivery systems, which are a f...

Open access Research Article 10.9734/jamps/2022/v24i330288

Knowledge and Use of Oral Rehydration Solution in the Management of Childhood Diarrhoea among Mothers in a Tertiary Health Facility in Port-Harcourt, Nigeria

C. Okechukwu, A. Alabi & LE. Yaguo-Ide · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Introduction: Oral rehydration solution (ORS) has been a life-saving remedy in the home and hospital management of dehydration, particularly in infants and children under the age of five. The improper use has however resulted in morbidity and mortality in children. The purpose of...

Open access Research Article 10.9734/jamps/2022/v24i230287

Hypoglycemic and Antihyperlipidemic Effects of Ethanolic Fruit Peel Extract of Carica papaya (pawpaw) in an Alloxan-induced Diabetic Rats

M. Haruna, Y. Abdulmumin, T. M. Abdulmumin, M. Murtala & M. M. Dalhatu · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background:  Diabetes mellitus is a severe health concern that is usually linked to a person's lifestyle and genetic variables. Its frequency of occurrence is alarming. Anti- diabetics drugs are costly and come with adverse effects. This study aims to evaluate the phytochemical,...

Open access Research Article 10.9734/jamps/2022/v24i230285

Dexamethasone, Interleukin 6, and the Adrenal Gland are the Real Battles for COVID-19: Our Molecular Docking, Physiological, and Immunological Explanations of Why the Clinical Benefit of Dexamethasone is More Evident in Males

Amr Ahmed, Randa Mohamed M. A. Farag, Samar M. Hussein Algendy, Asmaa Houjak & Mahmoud Elkazzaz · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

More than two years have passed since the pandemic and despite all the efforts of researchers, the pathogenesis of the SARS-CoV-2 has not yet been resolved. The SARS-CoV-2 coronavirus that causes COVID-19 has high ability of mutation resulting in different variants of the virus....

Open access Research Article 10.9734/jamps/2022/v24i230284

Study of Cranial Capacity among Igbo Adolescents in Southeastern Nigeria

Ezeokoli Uzo Victory & Ukoha Ukoha · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

This work was aimed at comparing cranial capacity and multiple intelligence in Anambra adolescents. Three hundred and eighty three subjects were enlisted in the study, comprising 228 females (59.5%), and 155 males (40.5%), with an age range of 10-19 years. Each subject filled the...

Open access Research Article 10.9734/jamps/2022/v24i230283