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All published articles 883

Development and Validation of Novel Analytical Method for the Determination of Particle Size Distribution in Ciprofloxacin Hydrochloride Using Laser-based Particle Size Analyzer

Amit Gosar, Chetana Parange, Suyog Narvankar, Shivaji Jadhav & Vikram Patil · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

This paper described a rugged and precise particle size determination method that has been developed and validated for the determination of particle size distribution of Ciprofloxacin Hydrochloride by a dry method using Malvern Mastersizer 2000. The Method of the particle size di...

Open access Research Article 10.9734/jamps/2022/v24i730316

Pathological Changes among Norvegicus Rattus Exposed on Novel Smoked Bambusa Vulgaris (Bamboo) Leaf: Cigarette Substitute during COVID-19 Lockdown in Nigeria

Nnaemeka Okorie, Olayinka Catherine Adeniran, Okafor Patrick Adimabua, Emmanuel Ifeanyi Obeagu & Ezaka, Ebere Anastasia · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: This research titled; Pathology changes among Norvegicus Rattus exposed on novel smoked Bambusa vulgaris: Cigarette substitute during COVID 19 lockdown in Nigeria is stimulated following increase use of the aforementioned substances as a substitute to drugs during cov...

Open access Research Article 10.9734/jamps/2022/v24i730314

Research Advances Aimed at Prognosis and Treatment of Alzheimers Disease

Godwin Okoye & Rachel Vincent · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Alzheimer's disease (AD) continues to remain a public health concern especially for seniors globally. Increased life expectancy owing to improvement in medical advances may have increased AD's prevalence. It remains a matter of concern for stakeholders to look at progress made ov...

Open access Research Article 10.9734/jamps/2022/v24i730313

Ileum Histoarchitecture Following Aspartame Consumption: Assessment of Actions of Moringa oleifera Seed Extract

Christopher Chiedozie Mbadugha, Donatus Gabriel Edem, Iboro Efiong Edet, Iberi Patrick Amagwu, Francis Nkem Odinukaeze & Abasikponke Ralphael Godwin · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

This study aims to determine the effect of Moringa oleifera seed extract on ileum histoarchitecture following aspartame consumption. Twenty-seven adult male Albino Wistar rats were used for the study. They were divided into nine groups comprising of: group A (control), administer...

Open access Research Article 10.9734/jamps/2022/v24i730311

Antimicrobial Activities of the Endophytic Fungus, Fusarium equiseti, Isolated from The leaves of Ocimum gratissimum

Nnamdi Markben Adione, Ifeanyi Peter Onyeka, Chika Christiana. Abba, Nkeoma Nkasi Okoye, Peter Maduabuchi Eze, Blessing Ogechukwu. Umeokoli, OgechI Ozioma. Anyanwu & Festus Basden Chiedu Okoye · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Introduction: Fungal endophytes of medicinal plants origin are gaining increasing interest as sources of novel bioactive agents with therapeutic capacity. This study was designed to identify and evaluate secondary metabolites isolated from Fusarium equiseti; an endophytic fungus...

Open access Research Article 10.9734/jamps/2022/v24i730312

An Overview of Pharmacovigilance and Adverse Drug Reaction Monitoring of Drugs and Vaccines during the COVID-19 Pandemic

Estella Achick Tembe-Fokunang, Banin Andrew Nyuki, Joseph Fokam, Dobgima John Fonmboh, Kristen Nubia Kaba, Lovet Benyella Fokunang, François-Xavier Mbopi-Keou, Abena, Ondoua Obama Marie Therese, Ralf Duerr & Charles Ntungwen Fokunang · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Once a drug is approved in phase III of clinical trials, pharmacovigilance (PV) becomes very important for the surveillance of drug, vaccine or medical devices. PV constitutes part of the phase IV approval, which involves a study for collecting, detecting, and monitoring adverse...

Open access Research Article 10.9734/jamps/2022/v24i630308

Malaria and HIV Co-infection among COVID-19 Cohort in Selected Healthcare Facilities in Rivers State, Nigeria

Rhoda Nwalozie, Orevaoghene Evelyn Onosakponome, Asikiya Huldah Hanson & Jonathan Nyebuchi · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: The COVID-19 pandemic began while improvement in malaria control and elimination had reached a peak. COVID-19 affected routine services particularly those for other killer infectious diseases including, HIV/AIDS and Malaria. This resulted in slowing progress in achiev...

Open access Research Article 10.9734/jamps/2022/v24i630309

Evaluation of Plasma Levels of Interleukin 6 and Iron Status of Volleyball Players in a Nigerian University

Emmanuel Ifeanyi Obeagu, Chinecherem Cynthia Anierobi, Gloria Chizoba Eze, Chidimma Maureen Chukwueze, Rutendo Denise Makonyonga, Nkiruka Millicent Amadi & Rifkatu Hassan · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

To determine the levels of interleukin 6 (IL-6) and iron status of volleyball players in Madonna University, Elele, Rivers State, Nigeria. A total number of 80 subjects were recruited for the study, comprising of 40 subjects before playing volleyball (20 males and 20 females) and...

Open access Research Article 10.9734/jamps/2022/v24i630307

Evaluation of Heavy Metal Content and Human Health Risk Assessment of Water Leaf (Talinum triangulare) Grown on Arsenic Spiked Soils

H. A. Waribo, C. R. Kalu, E. O. Anyalebechi, O. N. Briggs & E. S. Bartimaeus · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

AIM: This study investigated the concentration of heavy metal (Arsenic), taken up by waterleaf plant cultivated in three contaminated soil type namely; sandy, loamy and clay. The health risk associated in exposing the waterleaf plants was accessed from the different soil types at...

Open access Research Article 10.9734/jamps/2022/v24i630306

Antimicrobial Resistance: Unexplained Failure to Antibiotic Therapy in a Case at Maluti Adventist Hospital Berea Lesotho

Lineo Nyenye & Azubuike Benjamin Nwako · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Aim: The aim of the present study was to highlight the presence and problem of antimicrobial resistance in our setting. Case Presentation: We present a 17-year old female with yellow offensive vaginal discharge, itchiness and lower abdominal pain of about two-weeks duration. She...

Open access Research Article 10.9734/jamps/2022/v24i630305

Congenital Heart Malformations in Iraq, a Review

Luma Ibrahim Khalel Al-Allaf & Rawa Younis Mahmmod · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: Heart malformations are among the commonest indications for admission to hospital and may causes mortality of children. There is a need to highlight this important medical issue as there is no review article on this subject in Iraq. Aim: This study aims to focus on th...

Open access Research Article 10.9734/jamps/2022/v24i530303

Cardiovascular Risk Indices in Apparently Healthy Individuals after 14 Days of Consumption of Costus afer Stem Extract

Ibiene Sarah Kalio, Okon, Abigail Effiong & Mina Josephine Iyama · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Costus afer has been used for both medicinal and nutritional purpose without adequate knowledge of its systemic effect. This study therefore, sought to determine the cardiovascular risk indices in fifteen (15) apparently healthy individuals aged between 20-35years after 14days of...

Open access Research Article 10.9734/jamps/2022/v24i530302

Use of Prazosin for Post-traumatic Stress Disorder in Adolescents is Associated with Longer Inpatient Psychiatric Hospitalization

Dina Khoury, Bao-Nhan Benjamin Nguyen, Laura Lai & David Safani · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Objectives: Prazosin has been shown to be effective in reducing PTSD-related nightmares in adolescents in outpatient studies with modest sample sizes. There are no data on the effects of prazosin on length of inpatient psychiatric hospitalization. Given prazosin’s adverse effects...

Open access Research Article 10.9734/jamps/2022/v24i530301

AmpC Beta-Lactamase Prevalence in Isolates of Escherichia coli and Klebsiella pneumoniae in Enugu, Nigeria

Uzoamaka Charity Maduakor, Immaculate C. Ajiromanus & Anulika Obianuju Onyemelukwe · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: Pathogenic bacteria with beta lactamase-resistant determinants have emerged, posing a worldwide health threat. They confer resistance to a large array of \(\beta\) -lactam agents and \(\beta\)-lactam inhibitors. Aim: This study evaluated the prevalence and resistance...

Open access Research Article 10.9734/jamps/2022/v24i530300

Polyethylene Glycol Conjugation for Solubility Enhancement of Cefadroxil, a Poorly Soluble Antibiotic

B. Jeevana Jyothi, Y. Keerthana & N. Deekshita Reddy · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Introduction: Cefadroxil is the most widely used antibiotic for many bacterial infections but has the drawback of poorly solubility. In an attempt to provide an easier technique which can be scaled up on large scale to provide a simple method to enhance its aqueous solubility, th...

Open access Research Article 10.9734/jamps/2022/v24i530299