Epilepsy is a chronic non-communicable brain disease affecting approximately 50 million people of all ages worldwide. Antiepileptic drugs (AEDs) are used to manage epileptic seizures. However, AEDs may fail to control seizure activity in some patients and may cause unwanted effec...
Open access
Research Article10.9734/jamps/2026/v28i8881
Background: Male infertility remains a significant reproductive health challenge. Seminal plasma biochemical markers, including fructose, zinc, and citric acid, play essential roles in sperm metabolism, motility, and overall reproductive function. Their evaluation alongside sperm...
Open access
Research Article10.9734/jamps/2026/v28i8880
Background: Hypertension is highly prevalent among Black adults and contributes substantially to stroke, heart failure, kidney disease, and premature cardiovascular morbidity. Thiazide and thiazide-like diuretics are widely recommended as foundational antihypertensive agents, but...
Open access
Research Article10.9734/jamps/2026/v28i8877
Limb-girdle muscular dystrophy type 2I, now designated R9 (LGMD2I/R9), is an autosomal recessive dystroglycanopathy caused by biallelic pathogenic variants in the fukutin-related protein (FKRP) gene. Loss of FKRP glycosyltransferase activity disrupts the ribitol-phosphate-mediate...
Open access
Research Article10.9734/jamps/2026/v28i8878
Sara S. Abdelrahim, Mohammed H. Alnazeer, Mawahib A. Mustafa, Safa A. Abdalla, Elkhanssa Abdelhameed Ahmed Elhag, Kannan O. Ahmed, Yasir S. Kheir, Elmoiz Babekir & Bashir A. Yousef·Journal of Advances in Medical and Pharmaceutical Sciences·2026
Background: Imatinib mesylate is a tyrosine kinase inhibitor that has transformed the treatment of chronic myeloid leukaemia. However, information on its real-world use among sub-Saharan African populations remains limited. Aims: This study evaluated early haematological response...
Open access
Research Article10.9734/jamps/2026/v28i8879
Background: Malaria mortality studies in Ghana and sub-Saharan Africa have commonly relied on traditional regression approaches or generalised additive models, which may not fully represent delayed transmission effects, nonlinear exposure-response patterns, or uncertainty in mort...
Open access
Research Article10.9734/jamps/2026/v28i7876
Vitamin D is important for calcium homeostasis and skeletal health, while obesity may influence circulating vitamin D concentrations through altered metabolism and adipose tissue sequestration. This study assessed vitamin D status and selected biochemical markers related to bone...
Open access
Research Article10.9734/jamps/2026/v28i7875
Stage IV non-small cell lung cancer (NSCLC) has long been treated as a domain for systemic therapy and palliation alone, with surgery reserved for managing complications rather than for controlling disease. That position has shifted markedly over the past decade. It is now recogn...
Open access
Research Article10.9734/jamps/2026/v28i7874
Background: The Niger Delta region of Nigeria hosts one of the largest crude oil reserves in Africa. Decades of oil exploration and production have released a wide range of toxic heavy metals into the environment. While lead (Pb), cadmium (Cd), and nickel (Ni) have attracted cons...
Open access
Research Article10.9734/jamps/2026/v28i7872
Background: Thoracic involvement in Behçet’s disease (BD) is uncommon but is associated with significant morbidity and mortality, mainly due to vascular complications. Aim: This study aimed to evaluate thoracic manifestations of Behçet’s disease, excluding cardiac involvement, in...
Open access
Research Article10.9734/jamps/2026/v28i7871
Background: Periodontal diseases are associated with dysbiotic biofilms, and adjunctive strategies to chlorhexidine (CHX) are being explored because repeated antiseptic use may be accompanied by undesirable effects. This controlled in vitro study compared 0.12% CHX, Lactobacillus...
Open access
Research Article10.9734/jamps/2026/v28i7870
The utilisation of digital twins in conjunction with predictive analytics has seen a marked rise in its promotion for applications in personalised patient monitoring, treatment planning and service optimisation. Nevertheless, the extent to which these claims are substantiated by...
Open access
Research Article10.9734/jamps/2026/v28i7869
Child undernutrition remains a major public health challenge in many developing countries, including Rwanda, where environmental and climatic factors can adversely affect maternal and child health. This study analyzes the impact of in utero exposure to weather shocks on the nutri...
Open access
Research Article10.9734/jamps/2026/v28i6866
Diabetes mellitus is associated with significant disturbances in protein metabolism and renal function, contributing to disease progression and complications. This study evaluated the effect of Cucurbita maxima (pumpkin) on serum protein profile and renal biomarkers in alloxan-in...
Open access
Research Article10.9734/jamps/2026/v28i6867
Background: Inflammation is a protective physiological response to harmful stimuli, but excessive inflammation can contribute to tissue damage and disease. Conventional anti-inflammatory drugs are effective but may produce adverse effects with prolonged use. Flavonoids from plant...
Open access
Research Article10.9734/jamps/2026/v28i6865