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All published articles 883

In vitro Antioxidant Activity and Free Radical Scavenging Abilities of Ocimum gratissimum Leaf Extract

Moneme, E. C., Onochie, A. U., Onuegbu, M. E., Anyanwu, R. O., Ajakpofo, F. O. & Oladejo, A. A. · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

In recent years, researchers have intensified the search for effective, non-toxic, natural edible plants with free radical scavenging activity whose effects are cushioned by antioxidant molecules. This study evaluated the in vitro antioxidant activity and free radical scavenging...

Open access Research Article 10.9734/jamps/2025/v27i3758

Evaluation of Alpha-amylase and Alpha-glucosidase Activities of Brahmi Nei: An In-vitro Study

Shalini S, Rakshana N & Menaka R · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

α-amylase and α-glucosidase enzymes break down carbohydrates, leading to spikes in postprandial glucose levels in diabetic patients. Suppression of these enzyme activities helps regulate blood glucose levels and lower the risk of diabetes complications. Brahmi together with Ghee...

Open access Research Article 10.9734/jamps/2025/v27i3757

Comparative Analysis of Aromatic Properties of Fresh and Dried Date Seed Cinders Using IR and UV Spectroscopy in Accordance with ICH Guidelines

Rashyap Saraswat, Ankita Raikwar & Subhranshu Panda · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Date seeds being a source of edible oil, also used as a functional food ingredient because they are a good source of dietary fiber, phenolic compounds and antioxidants. This research includes study of aromatic property by UV Visible Spectroscopy and Fourier-transform...

Open access Research Article 10.9734/jamps/2025/v27i3756

Evaluating Multidisciplinary Learning in Pharmacy Education: Insights from Southern Nigeria

Opemipo Ephraim-Emmanuel, Adaobi Chioma Ezike & Elijah Nurudeen A Mohammed · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Pharmacy practice has increasingly focused on pharmaceutical care from traditional product-centred approaches, and now emphasizing multidisciplinary patient management, which requires a collaborative, multidisciplinary approach. This has necessitated a reassessment of...

Open access Research Article 10.9734/jamps/2025/v27i3755

Assessment of Enablers and Barriers to Childhood Immunisation in Gassol Local Government Area of Taraba State, Nigeria

Philemon Babylon, Abubakar Salim Aliyu, Phillips Aiyagbonrhule, Abubakar Sadiq, Musa Enyibi Solomon & Christiana Adamu Yamusa · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Childhood immunization remains a critical public health strategy to reduce morbidity and mortality associated with vaccine-preventable diseases. This study assesses the enablers and barriers to childhood immunization in Gassol Local Government Area (LGA) of Taraba State, Nigeria,...

Open access Research Article 10.9734/jamps/2025/v27i3754

Supplement Use among Hypertensive Patients in Two Rural and Two Urban Health Centers in Guyana, South America

Kissa Pitt, Jaidi Blasse, Zahir Yusuf, Jewel Edmondson-Carter, Cecil Boston & Andrew Hutson · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Objective: This study aimed to comparatively assess the knowledge and practices related to the use of dietary supplements as adjunctive treatment and management for hypertension among patients attending two rural and two urban health centers in Guyana. Methods: A cross-sectional,...

Open access Research Article 10.9734/jamps/2025/v27i3753

Antioxidative Potential of Telfairia occidentalis Aqueous Leaves Extract in Mitigating Cyclophosphamide-Induced Neurotoxicity in Wistar Rats

Abdulsalam Motunrayo Khadijat, Adejinmi Suliat Opeyemi, Oresanya Motunrayo Eunice, Ehiremen Samuel Ehimare, Taiwo Hassan Bello, Taiwo-Ola Dorcas Olubunmi, Adelakin Lola Adeola, Suleiman Isa A & Fakunle Ponle Bamidele · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aim: This study sought to investigate the antioxidative potentials of Telfairia occidentalis aqueous leaves extract (TOAE) on cyclophosphamide (CP) induced neurotoxicity in rats. Study Design: This study sought to investigate the antioxidative potentials of Telfairia occidentalis...

Open access Research Article 10.9734/jamps/2025/v27i2750

Potential Anti-hyperglycemic Activity of the Polyherbal Combination of Carica papaya L., Persea americana Mill., and Theobroma cacao L. Leaves Extract: In vitro, Ex vivo, In vivo Studies

Yawa Fernadette Clara Dackey, Dédé Mawulé Hanvi, Aku Enam Motto, Kokou Atchou, Povi Lawson-Evi & Kwashie Eklu-Gadegbeku · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: The present study evaluated the potential anti-hyperglycemic activity of a traditional recipe from Togo, consisting of C. papaya L., and P. Americana Mill. and T. cacao L., commonly used to treat diabetes. Study design: In vivo, Ex vivo, and In vitro approaches were utilize...

Open access Research Article 10.9734/jamps/2025/v27i2751

Preventive Effects of Ocimum gratissimum (Lamiaceae) Leaf Decoction on Pilocarpine-induced Seizure and Anxiety in White Mice (Mus musculus Swiss)

Lamare Tchachoua Adrien, Ngo Ngimout Kidjama, Njapdounke Kameni Jacqueline Stéphanie, Hassan Madi, Ngassa Kimen Léocadie Flore, Wangbara Alkali Emmanuel, Midala Kodji Jean Jacques, Taiwe Sotoing Germain & Ngo Bum Elisabeth · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

The objective of this work was to evaluate the effects of leaf decoction of Ocimum gratissimum (24.4, 61, 122 and 244 mg/kg) on seizures and anxiety during pilocarpine-induced epileptogenesis in mice Mus musculus Swiss. To evaluate anticonvulsivant and anxiolytic effect of Ocimum...

Open access Research Article 10.9734/jamps/2025/v27i2749

In vitro Analysis of the Pharmaceutical Interactions between Verapamil Hydrochloride and Citric Acid

Kazi Aysha Akter, Md. Mohiuddin Rahaman Rakib, Mokta, Mst Nasrin Khatun & Maliha Monoara Oafa · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

The objective of this study is to investigate the combination of drug-drug interactions involving different functional groups by assessing the interaction of a BCS class IV compound (Verapamil Hydrochloride) with Citric acid in various ratios, thereby enhancing the understanding...

Open access Research Article 10.9734/jamps/2025/v27i2748

Administration of Exosome-based Treatment for Exogenous Ochronosis Caused by Prolonged Use of Topical Hydroquinone

Danielle Karen Widjaja, I Made Winarsa Ruma, I Gusti Ayu Widianti & Vania Kwanda · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Objective: Exogenous ochronosis is a rare but challenging skin condition caused by prolonged misuse of hydroquinone-containing creams, with limited effective treatments. This study aimed to evaluate the effectiveness of exosome-based therapy as a novel therapeutic approach for th...

Open access Research Article 10.9734/jamps/2025/v27i2747

Preclinical Evaluation of the Anti-inflammatory Properties of Plants Extracts of Ficus exasperata (Moraceae) on Wistar Rat Models

Bate Antuan Asue, Edith Lem Abongwa, Vanessa Tchadji Mayoudom, Bayaga Herve Narcisse, Ndikum Valentine, Lovet Benyella Fokunang, Njinkio Nono Borgia, Estella Tembe-Fokunang, Bathelemy Ngameni, Sameh Abouzid & Charles Ntungwen Fokunang · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: In view of the rising global death rate associated with inflammatory diseases, a cost friendly, more effective and, safer drug with lesser side effects is needed.  Inflammation is a part of the complex biological response of vascular tissue to harmful stimuli, such...

Open access Research Article 10.9734/jamps/2025/v27i1746

Innovative Approaches in Glioblastoma Treatment: The Role of Optune in Enhancing Patient Survival

Ashvin Kumar, Nicholas Truong & Rahul Jandial · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Glioblastoma multiforme (GBM) is the most common form of malignant primary brain and CNS (central nervous system) tumors in adults. Prognosis is generally poor and the current standard for treatment often fails to meet expectations. In recent years, Optune has garnered attention...

Open access Research Article 10.9734/jamps/2025/v27i1745

Evaluation of Anticancer, Thrombolytic and Antimicrobial Activities of Heliotropium indicum (Indian turnsole)

Kazi Fabliha Anjum, Al Farabe, Abu Jubaer Asif, Khadizatul Kubra & Khandaker Antara Anika · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

This research objective was to investigate some in vitro properties of methanol-extracted plant extracts of Heliotropium indicum (Indian turnsole). The primary method of assessment for the methanolic extract of Heliotropium indicum (MEHI) was investigated for phytochemical screen...

Open access Research Article 10.9734/jamps/2025/v27i1744

Impact of Integrated Interventions of Prescriber Education and De-escalation Strategies on Implementing WHO Access: Insights from a South Indian Tertiary Care Setting

Jasper Victoria Leelarani Martinraj, Harini. S, S. Bibila, Feba Mary Thomas & Keren Ann George · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: This study evaluates the effect of integrated interventions including prescriber education and de-escalation strategies on improving antibiotic prescribing practices, optimizing the Access: Watch ratio, reducing Reserve antibiotic use, and improving Length of Therapy (LOT)...

Open access Research Article 10.9734/jamps/2025/v27i1743