Background: Drug-resistant tuberculosis (DR-TB) remains a public health challenge in Kenya despite advances in diagnosis and shorter, all-oral treatment regimens. Aim: This study assessed patient characteristics influencing DR-TB treatment outcomes in Meru County, Kenya. Methods:...
Open access
Research Article10.9734/jamps/2026/v28i10894
Background: Breast cancer remains the most common cancer among women worldwide and a major cause of preventable cancer mortality, particularly in resource-constrained settings where delayed presentation is common. Breast self-examination (BSE) does not replace clinical assessment...
Open access
Research Article10.9734/jamps/2026/v28i10895
Aims: To characterize transcriptomic alterations associated with major depressive disorder (MDD) in postmortem human brain tissue and integrate differential gene-expression findings with protein-protein interaction, functional-enrichment, and drug-gene interaction analyses. Study...
Open access
Research Article10.9734/jamps/2026/v28i10896
Aims: To synthesise and critically appraise evidence on artificial intelligence (AI) and multimodal data approaches for diagnosis, prognosis, and treatment decision support in diffuse large B-cell lymphoma (DLBCL) and acute myeloid leukaemia (AML), and to compare how disease biol...
Open access
Research Article10.9734/jamps/2026/v28i10893
Background: Self-medication is a global public health practice conventionally dominated by analgesics, antipyretics and antimicrobials, yet the demographic structure of this behaviour and its association with information sources remain poorly characterised in Nigerian community p...
Open access
Research Article10.9734/jamps/2026/v28i9892
Imaging-based screening programmes are constrained by two opposing failures: false-positive results that generate unnecessary recall, anxiety, further imaging and biopsy, and false-negative results that permit disease to progress undetected until the next screening round or until...
Open access
Research Article10.9734/jamps/2026/v28i9891
Osteogenesis imperfecta is the prototypical heritable disorder of bone fragility, and the last three decades have transformed it from a clinically defined syndrome into a molecularly stratified group of conditions involving more than twenty genes. That transformation has not been...
Open access
Research Article10.9734/jamps/2026/v28i9890
Glucagon occupies an unusual position in clinical endocrinology. The same 29-amino-acid peptide serves as a provocative agent for pituitary function testing, as an emergency treatment for severe hypoglycaemia, as a continuous infusion in hyperinsulinaemic states of infancy, and,...
Open access
Research Article10.9734/jamps/2026/v28i9889
Particle size distribution (PSD) characterisation is important for pharmaceutical drug-substance quality because particle size can influence formulation-related performance. This study developed and validated a wet-dispersion laser-diffraction method for determining the PSD of Al...
Open access
Research Article10.9734/jamps/2026/v28i9887
Hospital systems are adopting predictive analytics and artificial intelligence at a pace that has outstripped the development of the organisational machinery required to supervise them. Two bodies of scholarship have grown in parallel to address this problem. The first proposes g...
Open access
Research Article10.9734/jamps/2026/v28i9888
Background: Immune-mediated diseases impose substantial clinical and socioeconomic burdens, while prolonged use of conventional immunosuppressive agents may be associated with serious adverse effects. Fisetin, a naturally occurring flavonoid, has demonstrated anti-inflammatory an...
Open access
Research Article10.9734/jamps/2026/v28i9886
Digital health programmes are commonly monitored through separate clinical, operational and financial reporting systems. This fragmentation obscures whether a programme that is technically delivered and operationally adopted also improves patient outcomes, distributes benefits eq...
Open access
Research Article10.9734/jamps/2026/v28i9885
Explainable artificial intelligence is widely promoted as the mechanism through which opaque deep learning systems will earn the confidence of clinicians and improve diagnostic performance in medical imaging. The claim has acquired regulatory and commercial momentum faster than i...
Open access
Research Article10.9734/jamps/2026/v28i8884
Introduction: Estrogen receptor-positive/HER2-negative breast cancer is the most common molecular subtype of breast cancer. Aromatase inhibitors such as letrozole are part of the standard endocrine treatment regimen for postmenopausal patients; however, real-world evidence on pat...
Open access
Research Article10.9734/jamps/2026/v28i8883
Concentration measurements of drugs and their metabolites in biological matrices underpin regulatory decisions on safety, efficacy and labelling, and the technical requirements governing those measurements were, for three decades, set regionally. Guideline M10 of the Internationa...
Open access
Research Article10.9734/jamps/2026/v28i8882