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Hepatoprotective Activity of Rubia tinctorum’s Extract against CCl4 Induced Hepatic Injury in Rats

Fatimazahra Marhoume, Younes Zaid, Hicham Boufous, Nadia Errafiy, Mehdi Ait Laaradia, Jawad Laadraoui, Abde lmalek Hakmaoui, Abdellah Bagri & Abderahmane Chait · European Journal of Medicinal Plants · 2017

This study investigated the hepatoprotective activity of Rubia tinctorum’s extract against CCl4 induced liver damage in rats. Twenty four rats were divided into four groups. Group I received normal saline (10 ml/kg) and group II (normal control) was treated with vehicle (olive oi...

Open access Research Article 10.9734/EJMP/2017/35441

Ameliorative Potentials of Methanol Extract and Chloroform Fraction of Drymaria cordata on MSG-induced Uterine Hyperplasia in Female Wistar Rats

A. O. Olowofolahan, O. O. Aina, E. T. Hassan & O. O. Olorunsogo · European Journal of Medicinal Plants · 2017

Aim: Uterine fibromyomas are non-cancerous or benign growth of the uterus. They are sensitive to changes in levels of oestrogen and progesterone which affect the size of the fibroid. It has been well established that glutamate, a naturally occurring amino acid induces uterine fib...

Open access Research Article 10.9734/EJMP/2017/36335

In vitro Antioxidant, Antimicrobial, Insecticidal and Cytotoxic Activities of the Medicinal Plants: Allamanda cathartica and Mimusops elengi

Md. Abdul Mannan, Md. Shamsul Alam, Farhana Mustari, Md. Kudrat-E-Zahan, Roushown Ali, A. B. M. Hamidul Haque, Shahed Zaman & Debashish Talukder · European Journal of Medicinal Plants · 2017

A comparison of in vitro antioxidant, antimicrobial, insecticidal and cytotoxic activities of two medicinal plants, Allamanda cathartica and Mimusops elengi have been studied by spectrophotometric and disk diffusion methods in this research. It was observed that different leaf ex...

Open access Research Article 10.9734/EJMP/2017/35730

Antibacterial Activity of Methanolic Extracts of Euphorbia heterophylla and Tithonia diversifolia against Some Microorganisms

B. A. Oso & T. A. Ogunnusi · European Journal of Medicinal Plants · 2017

Aims: To determine the antibacterial activities of methanolic extracts of Euphorbia heterophylla and Tithonia diversifolia on clinical isolates. Place and Duration of Study: The study was carried out at Afe Babalola University and the plants were collected from the campus. The is...

Open access Research Article 10.9734/EJMP/2017/28568

A Systematic Analysis of Prunus Species with a Focus on Management Plan of Prunus africana (Hook.f.) Kalkman: An Autochthon Plant of Africa

Maninder Karan, Ashish Kumar Jena, Neetika Sharma & Karan Vasisht · European Journal of Medicinal Plants · 2017

Aims: To provide complete data on the alike and differentiating characters of the bark of six species of Prunus i.e. P. amygdalus Stokes, P. armeniaca L., P. cerasoides Buch.-Ham. ex D.Don, P. domestica L. and P. persica  (L.) Batsch vis-a-vis P. africana (Hook.f.) Kalkman of fam...

Open access Research Article 10.9734/EJMP/2017/35897

Phytochemical Composition and Free Radicals Scavenging Activities of Methanolic Leaf Extract of Napoleona imperialis

O. E. Etim, F. M. Awah, U. E. Bassey, E. I. Akpakpan & M. N. Udo · European Journal of Medicinal Plants · 2017

Aims: Napoleona imperialis is a wild plant commonly found in Southeastern part of Nigeria used mostly for the treatment of wounds. The methanolic leaves extract of Napoleona imperialis was qualitatively and quantitatively analyzed for the presence of bioactive secondary metabolit...

Open access Research Article 10.9734/EJMP/2017/33139

Anti-diabetic Effect of Anthocleista vogelii Ethanolic Root Extract and Fractions in Streptozotocin-induced Diabetic Albino Rats

Rita Maneju Sunday, Olugbenga Ayodeji Ayannuga, Joseph A. Ibeh, Lucky Abdul Ajige, Olusegun Julius Oyedele, Bartholomew Okechukwu Ibeh, Efere Martins Obuotor & Olapade Rufus Ilesanmi · European Journal of Medicinal Plants · 2017

Aims: To investigate the anti-diabetic effect of Anthocleista vogelii root ethanolic extract (EE) and fractions (ethyl acetate [EF], dichloromethane [DF] and n-hexane [HF] fractions) in streptozotocin (STZ)-induced diabetic albino rats. Study Design: The antidiabetic effect of A....

Open access Research Article 10.9734/EJMP/2017/35483

Toxicity of Anchomanes difformis, An Antimalarial Herb in Murine Models

J. O. Olanlokun, C. O. Babarinde & O. O. Olorunsogo · European Journal of Medicinal Plants · 2017

Aim: Anchomanes difformis (A. difformis) is commonly used in folkloric medicine for the treatment of malaria. However, there had been no scientific evidence to substantiate this folkloric claim in murine models; hence the study. Study Design: We employed murine models for this in...

Open access Research Article 10.9734/EJMP/2017/35165

Genetic Analysis of the Bletillae Rhizoma and Its Common Adulterants Using Internal Transcribed Spacer 2 Molecular Barcoding

Ye Lu, Shaohuan Liu, Baoling Ju & Jin Wang · European Journal of Medicinal Plants · 2017

Aim: This study was designed to discriminate Bletillae Rhizoma from its common adulterants: Iris tectorum, Polygonatum odoratum and Polygonatum cyrtonema using molecular barcoding. Place and Duration of Study: Department of Traditional Chinese Medicine, College of Pharmaceutical...

Open access Research Article 10.9734/EJMP/2017/35791

Ashwagandha and Its Active Ingredient, Withanolide A, Increase Activation of the Phosphatidylinositol 3’ Kinase/Akt Cascade in Hippocampal Neurons

Dahae Hwang, Isabel Vasquez, Leticia Galvez, Huong Do, Anthony Lopez de Santa Ana, Shane Matta, Feimeng Zhou, Michael Chen & Amelia Russo-Neustadt · European Journal of Medicinal Plants · 2017

Aims: To determine if whether, in a hippocampal neuron culture model subjected to nutrient deprivation stress (simulating degenerative disease state), Ashwagandha and/or two of its putative active ingredients, withanolide A or withaferin A, affect any of the following: neurite ou...

Open access Research Article 10.9734/EJMP/2017/35355

Antidiabetic Activities of the Aqueous Root Bark and Flower Extracts of Terminalia catappa on Streptozotocin - Induced Diabetes in Male Wister Rats

Comfort Japhet Philip, Luka D. Carrol, Ishaya Y. Longdet & Aguiyi J. Chinyere · European Journal of Medicinal Plants · 2017

Diabetes mellitus is a disease associated with the increase in Blood glucose level caused by the abnormalities of glucose receptors in the uptake of glucose or total destruction of the β pancreatic cell, with approximately 366 millions of people worldwide diagnosed with the disea...

Open access Research Article 10.9734/EJMP/2017/34702

The Effect of Hydroalcoholic Extract of Ferulago angulata on Liver Function Parameters and Antioxidant Status in Alloxan-Induced Diabetic Rats

Seyedeh-Fatemeh Mousavi-Ezmareh, Mohammad Mazani, Esfandiar Heidarian, Reza Alipanah Moghadam, Mahmoud Rafieian-kopaei, Garshasp Mardanian, Lotfollah Rezagholizadeh & Ali Shamsazar · European Journal of Medicinal Plants · 2017

Aim: The aim of this study was to evaluate the hepatoprotective and antioxidant activities of Ferulago angulata Extract (FAE) in experimental diabetic rats. Materials and Methods: 54 adult male Wistar rats divided into 6 groups (n=9). Diabetes was induced in all animals except th...

Open access Research Article 10.9734/EJMP/2017/35134

Anti-microbial Activities of Selected Ghanaian Medicinal Plants and Four Structurally Similar Anti-protozoan Compounds against Susceptible and Multi-drug Resistant Bacteria

A. N. Antwi, K. B. A. Owusu, M. Amoa-Bosompem, N. B. Williams, F. Ayertey, L. Akyeh, J. Agyapong, T. Tetteh, G. I. Djameh, S. K. Botchie, F. Azerigyik, A. Ablordey, N. H. Tung, A. A. Appiah, S. Iwanaga, Y. Shoyama, N. Ohta, B. Egyir & M. Ohashi · European Journal of Medicinal Plants · 2017

Antibacterial resistance is one of the fast rising health concerns globally. WHO emphasized the need for development of new drugs to combat antimicrobial resistance. Our group previously found several anti-protozoan compounds: ML-2-3, Molucidin and ML-F52 from a Ghanaian medicina...

Open access Research Article 10.9734/EJMP/2017/35437

Effect of Methanolic Leaf Extract of Carica papaya on Plasmodium berghei Infection in Albino Mice

Ishaya Y. Longdet & Emmanuel A. Adoga · European Journal of Medicinal Plants · 2017

Aim: The work was designed to investigate the antmalarial activity of methanolic leaf extract of Carica papaya on Plasmodium berghei NK65 strain infection in vivo. Place and Duration of Study: Department of Biochemistry and National Institute of Pharmaceutical Research and Develo...

Open access Research Article 10.9734/EJMP/2017/34698

Therapeutic Effect of Nigella sativa on Alcohol-induced Liver Disease in Rats

A. Mosbah, H. Zettal, H. Khither, C. Mosbah, N. Kacem Chaouche & M. Benboubetra · European Journal of Medicinal Plants · 2017

Background: Alcohol-induced fatty liver disease is the earliest liver disorder associated with excessive consumption of alcohol. Various treatment regimens have been proposed for the treatment of alcohol-induced liver disorders including the use of medicinal plants such as Nigell...

Open access Research Article 10.9734/EJMP/2017/34661