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All published articles 997

Metabolite Space of Rheumatoid Arthritis

Herman van Wietmarschen & Jan van der Greef · Journal of Advances in Medicine and Medical Research · 2012

Metabolites play numerous roles in the healthy and diseased body, ranging from regulating physiological processes to providing building blocks for the body. Therefore, understanding the role of metabolites is important in elucidating the etiology and pathology of diseases and fin...

Open access Research Article 10.9734/BJMMR/2012/1577

Use of the Valsalva Maneuver in Addition to Controlled Hypotension During Endovascular AVM Embolization: A Novel Approach to Reducing Distal Particle Embolization?

Eric A. Harris MD, MBA · Journal of Advances in Medicine and Medical Research · 2012

Study Objective: To report the use of a sustained Valsalva maneuver during deliberate hypotension in order to reduce the incidence of distal particle embolization during the neuroangiographic embolization of intracranial arteriovenous malformations (AVMs). Design: Retrospective c...

Open access Research Article 10.9734/BJMMR/2012/1349

Drug Resistance in Mycobacterium tuberculosis Isolates from Northeastern Sudan

S. O. Hassan, M. T. Musa, H. M. Elsheikh, A. M. S. Eleragi & N. S. Saeed · Journal of Advances in Medicine and Medical Research · 2012

The present study intended to determine the drug resistance patterns of Mycobacterium tuberculosis isolates among human new tuberculosis cases from northeastern Sudan using conventional and molecular techniques. Of 100 mycobacterial isolates tested by proportion method, 6% and 2%...

Open access Research Article 10.9734/BJMMR/2012/1404

Psychotropic Medications and QTc Parameters in a Nigerian Cohort

P. M. Kolo, P. O. Ajiboye, A. D. Yusuf, A. B. Omotoso & E. O. Okoro · Journal of Advances in Medicine and Medical Research · 2012

Aims: Evidence is increasing to indicate that individuals with mental illness may be at risk of premature death. We studied the prevalence of QTc prolongation, QT dispersion (QTd) and cardiac arrhythmias in patients on psychotropic drugs. Study Design: Cross-sectional study. Plac...

Open access Research Article 10.9734/BJMMR/2012/1264

Abduction of Children by Their Parents: A Psychopathological Approach to the Problem in Mixed-Ethnicity Marriages

A. Douzenis, K. Kontoangelos, O. Thomadaki, G. N. Papadimitriou & L. Lykouras · Journal of Advances in Medicine and Medical Research · 2012

Aim: Child abduction by one parent and their transport to a foreign country is increasing worldwide but has not received adequate scientific interest. When inter-marital relationships reach the point of break-up and divorce, one of the parents abducts his/her child/children. Meth...

Open access Research Article 10.9734/BJMMR/2012/1137

Antibacterial Activity of Oenothera rosea (L ’Hér) Leaf Extracts

Ricardo Gomez-Flores, Raúl Reyna-Martínez, Patricia Tamez-Guerra & Ramiro Quintanilla-Licea · Journal of Advances in Medicine and Medical Research · 2012

Aims: To determine the antibacterial effect of Oenothera rosea against Escherichia coli, Salmonella enteritidis and Vibrio cholerae. Study Design: In vitro antibacterial study. Place and Duration of Study: Universidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Depar...

Open access Research Article 10.9734/BJMMR/2012/1480

6MWT Predicts Survival Better Than CPET in Patients with Stable Cardiomyopathy

Carlo Rostagno, Vieri Boddi & Gian Franco Gensini · Journal of Advances in Medicine and Medical Research · 2012

Aims: The prognostic value of different clinical, echocardiographic and functional parameters was evaluated in clinically stable outpatients with heart failure due to idiopathic dilated cardiomyopathy (DCM). Study Design: Observational prospective study. Methodology: 56 patients...

Open access Research Article 10.9734/BJMMR/2012/1251

Endothelial Dysfunction: An Early Cardiovascular Risk Marker in Asymptomatic Obese Individuals with Prediabetes

Alok K. Gupta, Eric Ravussin, Darcy L. Johannsen, April J. Stull, William T. Cefalu & William D. Johnson · Journal of Advances in Medicine and Medical Research · 2012

Aims: To elucidate if endothelial dysfunction is an early CV risk marker in obese men and women with prediabetes. Study Design: Cross-sectional study. Place and Duration of Study: Clinical Research Unit, Pennington Biomedical Research Center, Baton Rouge, LA. United States. Metho...

Open access Research Article 10.9734/BJMMR/2012/1479

YKL-40: a Potential Biomarker and Therapeutic Target for Breast Cancer Diagnosis and Therapy

Rong Shao · Journal of Advances in Medicine and Medical Research · 2012

Over the past two decades, emerging data have found that YKL-40, a secreted glycoprotein, is elevated in a broad spectrum of human diseases including cancers, liver injury, asthma, diabetes, inflammatory diseases, and cardiac disorders. In breast cancer, increased serum levels of...

Open access Research Article 10.9734/BJMMR/2012/1282

Differential Effects of Anaesthesia on the phMRI Response to Acute Ketamine Challenge

Duncan J. Hodkinson, Carmen de Groote, Shane McKie, J. F. William Deakin & Steve R. Williams · Journal of Advances in Medicine and Medical Research · 2012

Aims: Pharmacological-challenge magnetic resonance imaging (phMRI) is powerful new tool enabling researchers to map the central effects of neuroactive drugs in vivo. To employ this technique pre-clinically, head movements and the stress of restraint are usually reduced by maintai...

Open access Research Article 10.9734/BJMMR/2012/1412

Menstrual Pattern among Female Medical Students in University of Maiduguri, Nigeria

Danladi Sambo Amaza, Nuhu Sambo, Joseph Vandi Zirahei, Mohammed Babagana Dalori, Helga Japhet & Hamdalat Toyin · Journal of Advances in Medicine and Medical Research · 2012

Aims: To determine menstrual pattern and disorder associated with it among female medical students. Study Design: Cross-sectional study. Place and Duration of Study: College of Medical Sciences, University of Maiduguri, Borno State, Nigeria between February – September 2010. Meth...

Open access Research Article 10.9734/BJMMR/2012/1018

Chronic Fluoxetine Administration during Different Postnatal Development Stages Leads to Stage Dependent Changes of Glial Fibrillary Acidic Protein Expression in Rat Brain

Nathalie Bock, Hannah Alter, Emre Koc, Veit Roessner, Aribert Rothenberger & Till Manzke · Journal of Advances in Medicine and Medical Research · 2012

Aims: Depressive symptoms in children and adolescents are commonly treated with serotonin re-uptake inhibitors like fluoxetine. Astrocytes expressing different serotonin receptors (5-HTRs) and the serotonin transporter (5-HTT) are affected by fluoxetine administration. The study...

Open access Research Article 10.9734/BJMMR/2012/1099

The Mismatch between Australian Population and General Practice Medical Workforce

Tony Bakare, Wendy Moyle, Laetitia Hattingh & Peter Grimbeek · Journal of Advances in Medicine and Medical Research · 2012

Aims: To review and analyse Australian general practitioner’s workforce data for the 2000 to 2010 period by comparing this to Australian population trends and to make informed recommendations about GP workforce planning. Study Design: Descriptive analysis of the available Austral...

Open access Research Article 10.9734/BJMMR/2012/1075

Sudden Bilateral Blindness Following Massive Uterine Bleeding: Reports of 2 Cases

Chinyere Nnenne Pedro-Egbe & Elizabeth Awoyesuku · Journal of Advances in Medicine and Medical Research · 2012

Background: Most cases of sudden blindness are due to vascular causes. Ischemic optic neuropathy is a rare cause of blindness reported most commonly in association with collagen-vascular diseases, infectious processes, and systemic hypotension related to massive exsanguinating he...

Open access Research Article 10.9734/BJMMR/2012/1000

High Membrane Cholesterol in CLL B-Cells and Differential Expression of Cholesterol Synthesis Genes in IG GENE-Unmutated vs Mutated Cells

Cécile Tomowiak, Anne Kennel, Hélène Gary-Gouy, Nader Hadife, Pierre Feugier, Torsten Haferlach, Marie C Béné & Ali Dalloul · Journal of Advances in Medicine and Medical Research · 2012

Objectives: Chronic lymphocytic leukaemia (CLL) is associated with abnormalities of the B-Cell Receptor (BCR) signalling, including low responsiveness to antigenic stimulation and constitutive phosphorylation of several components of the signalling pathway. In B-cells, BCR-mediat...

Open access Research Article 10.9734/BJMMR/2012/944