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Evaluation of the Therapeutic Potential of Ethanol Leaf Extract of Anacardium occidentale in the Management of Experimentally Induced Kidney Damage in Wistar Rat

Nweke Elizabeth Obioma, Chijioke, I. Ugboaja, Amah A. Kalu & Nweke Tochukwu Miracle · International Journal of Advances in Nephrology Research · 2022

The aim of this study was to evaluate the therapeutic potential of ethanolic leaf extract of A. occidentale in wistar rats. Freshly harvested leaves of A. occidentale were shade dried and ground to fine powder. 500 g of powdered plant sample was macerated in ethanol for 72 hrs. T...

Open access Research Article

Evaluation of Some Kidney and Liver Function Markers in Humans Exposed to Pesticides in Okagwe and Ihe-Nta, Abia State, Nigeria

O. M. Arunsi, C. I. Ikaraoha & H. U. Nwanjo · International Journal of Advances in Nephrology Research · 2022

Aim: To evaluate the levels of some kidney and liver function markers in humans exposed to pesticides in Okagwe and Ihe-Nta, Abia State, Nigeria. Study Design:  A cross-sectional study. Place and Duration of Study: Abia-ADP, Ohafia Zone and Department of Biochemistry, University...

Open access Research Article

Assessment of Renoprotective Effect of Pentaclethra macrophylla Seed (Ugba) against Mercury Induced Acute Kidney Injury in Male Albino Rats

J. D. Nwahiri, E. O. Nwachuku, D. G. Tamuno-Emine & E. S. Bartimaeus · International Journal of Advances in Nephrology Research · 2021

Aim: The aim of this study was to assess the renoprotective effect of Pentaclethra macrophylla seed (Ugba) against Mercury induced acute kidney injury in male Albino Rats. Study Design:  This is an interventional study. Place and Duration of Study: Department of Animal and Enviro...

Open access Research Article

Assessment of Chronic Toxicological Effects of 2, 2-Dichlorovinyl Dimethyl Phosphate (Sniper) on the Kidneys of New Zealand White Rabbits

C. C. Ozoemena, E. S. Bartimaeus, F. U. Igwe & E. O. Nwachuku · International Journal of Advances in Nephrology Research · 2021

Aim: The aim of this study was to assess the chronic toxicological effects of 2, 2-dichlorovinyl dimethyl phosphate (Sniper) on the kidneys of New Zealand white Rabbits. Study Design:  This is an experimental study. Place and Duration of Study: Department of Biological Science, R...

Open access Research Article

Evaluation of Endogenous Antioxidants and Kidney Function Indices in Albino Mice Infected with Plasmodium berghei and Treated with Sodium Bicarbonate

G. S. Haruna, M. H. Abdullahi, H. S. Abdullahi, S. Usman, J. M. Egbaloshu, T. O. Bamidele & M. Z. Zaruwa · International Journal of Advances in Nephrology Research · 2021

Malaria is an infectious disease that is transmitted through mosquito bites and is endemic especially in Sub-Saharan Africa. The current study aimed at evaluating the antioxidants and kidney function indices in albino mice infected with P. berghei and treated with sodium bicarbon...

Open access Research Article

Preventive Effect of L- Methionine on Potassium Bromate- Induced Nephrotoxicity in Wistar Rats

M. A. Kanadi, R. Yila, M. P. Ibrahim, A. I. Yaradua & A. Nasir · International Journal of Advances in Nephrology Research · 2021

Aim: To investigate the preventive potential of L-methionine against potassium bromate –induced nephrotoxicity in rats. Study Design: Twenty male Wistar rats were used. The rats were divided into four groups containing five rats per group as follows; normal control, KBrO3 control...

Open access Research Article

Exposure to Petrol on the Liver and the Kidneys of Auto-mechanics in Aba Metropolis South-East, Nigeria; Age and Duration Effects

Anya, Ojiugo Hannah, Nwachuku, Edna Ogechi, Bartimaeus, Ebirien-Agana Samuel & H. A. Waribo · International Journal of Advances in Nephrology Research · 2021

Aim: The aim of this study was assess exposure to petrol on the liver and the kidney of Auto-mechanics in Aba Metropolis, South-East, Nigeria, considering age and duration effects. Study design: This study is a cross-sectional study. Place and Duration of Study: Abia State Univer...

Open access Research Article

Hypoglycemic Potentials and Toxicity studies of Garcinia kola Seed Tincture in Alloxan-Induced Diabetic Rats

N. C. Wokne-Eze, T. G. Davies & E. S. Bartimaeus · International Journal of Advances in Nephrology Research · 2021

Aim: The aim of this study was to evaluate the hypoglycemic potentials and toxicity studies of Garcinia kola seed tincture in Alloxan-induced Diabetic Rats. Study Design: This study is an interventional study. Place and Duration of Study: A total of fifty one (51) adult wister ra...

Open access Research Article

Evaluation of Methanolic Extract of Bambara Nut on Renal Indices of Wistar Rats

A. I. Airaodion, A. U. Megwas, O. C. Njoku, P. N. Akunne & N. O. Oladosu · International Journal of Advances in Nephrology Research · 2021

Background: Bambara nut is a common household food in Nigeria especially among the Igbos of the South Eastern part of the country. Aim: This study is aimed at investigating the effect of Bambara nut on renal indices of Wistar rats. Methodology: The Songkhla 1 variety (red seed co...

Open access Research Article

Evaluation of Renal Function of Streptozotocin (STZ)-Induced Diabetic Albino Rats Treated with Syzygium aromaticum (Clove)

Sammy Joshua, Omuruka Sweeten & Chukwu Christopher Ifunaya · International Journal of Advances in Nephrology Research · 2021

Diabetes a chronic disorder of carbohydrate, fats and protein metabolism that is characterized by increasing levels of fasting and post prandial blood sugar. Syzygium aromaticum is a medicinal plant and well-utilized spice in the world. They are packed with essential vitamins, mi...

Open access Research Article

Nephrotoxicity of Ethanol Extract of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Uloaku Ogbuagu, Ifeoma N. Nweke & Prince C. Unekwe · International Journal of Advances in Nephrology Research · 2021

Background: The use of Xylopia aethiopica fruit in folklore medicine is on the increase without regard to its toxicity. Aim: This study was aimed at examining its toxicity on the kidney of Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted usi...

Open access Research Article

Effectiveness of Lavender Oil Application on Pain during Arteriovenous Fistula Puncture

P. Thenmozhi & K. Blessy Pauline · International Journal of Advances in Nephrology Research · 2020

Introduction: Patient undergoing hemodialysis experience constant fear and anxiety due to the pain during puncture of arteriovenous fistula. Pain management is one of the main focuses of caring patients, therefore should aim for effective pain management using complementary and a...

Open access Research Article

Assessment of Creatinine Levels in Blood and Saliva of Heamodialysed Subjects

C. Amadi, Fyneface, Konne, Joel Burabari & Konne, Felix Eedee · International Journal of Advances in Nephrology Research · 2020

The aim of this study was to determine if salivary creatinine responds to changes in concentrations in health, disease and treatment, and how these changes relate to changes in blood creatinine levels. Creatinine was assayed in both blood and saliva of 29 haemodialysed subjects;...

Open access Research Article