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All published articles 100

Behavioural Reactions of Random-Bred Mice under the Influence of Hypouricemia and Aegopodium podagraria L. Preparations

O. V. Tovchiga, S. Yu. Shtrygol’ & T. V. Gorbatch · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aims: Aegopodium podagraria L. preparations normalize uric acid metabolism and exert organoprotective effects. Still, their efficacy was not determined in combined use with therapeutic doses of allopurinol. This study addressed the changes of uric acid metabolism and CNS in mice...

Open access Research Article 10.9734/AJRIMPS/2018/42362

Ethanolic Seed Extract of Garcinia kola Reduces Epididymal Sperm Count and Some Serum Reproductive Hormone Concentrations in Adult Male Albino Wistar Rats

Emmanuel C. Okafor, Agbai E. Onuka, Idiongo O. Umoh & Felix N. Ugwu · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aims: This study aimed to elucidate the effect of Garcinia kola on serum reproductive hormones and sperm count in adult male albino Wistar rats. Study Design:  Albino rats were randomly assigned into 4 groups containing 7 rats each. Place and Duration of Study: Department of Huma...

Open access Research Article 10.9734/AJRIMPS/2018/42640

Characterization of Antibiotics Inhibitory to Methicillin Resistant Staphylococcus aureus (MRSA) from Soil Actinomycetes

Umar Abdullahi, John, Solomon Obidah & Suleiman Mahmoud Jada · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Actinomycetes are subgroup of actinobacteria which include Streptomyces, a source of many important antibiotics. Methicillin-resistant Staphylococcus aureus is one of the emerging infectious diseases which pose a significant health and occupational risk worldwide. The aim of this...

Open access Research Article 10.9734/AJRIMPS/2018/39742

Membrane Stabilizing Effects of Calcium in Salt-induced Hypertensive Pregnancy

A. A. Aigbiremolen, G. T. Olowe & C. P. Aloamaka · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Though Calcium is involved in the mechanisms of increase contractility, it has been shown that at high concentration, calcium ions may cause membrane stabilization in which case the smooth muscle responsiveness decreases. Theoretically, a decrease in membrane permeability to calc...

Open access Research Article 10.9734/AJRIMPS/2018/41586

Prevalence and Susceptibility Analysis of Gram Negative Pathogens in Tertiary Care Transplant Hospital, Mumbai

Niranjan B. Patil, Shetye Sharma, Manjusha Aggarwal, Mihir Vora, Zaheer Virani, Parijat Gupte & Bharat Shah · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Introduction: The susceptibility pattern of antibiotics varies in different geographical regions and needs to be updated regularly to guide clinicians in choosing appropriate empirical therapies. This study was aimed to evaluate the susceptibility pattern of Gram negative clinica...

Open access Research Article 10.9734/AJRIMPS/2018/41893

Anatomical Variations in the Brachial Artery, Extensor Carpi Radialis Longus and Musculocutaneous Nerve in Adult Male Sudanese Cadavers

Mohammed Abdelsalam Ahmed Abdelmotalab · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Knowledge of different variations is important for the clinicians and other medical disciplines for the diagnostic, interventional and surgical procedures. The aim of this study is to report any unusual observations of anatomical structures during the dissection of properly embal...

Open access Research Article 10.9734/AJRIMPS/2018/42617

Reliability of Urine Malaria Test (UMT) for Malaria Diagnosis

J. A. Okete, E. M. Oden & C. E. Adofikwu · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Although an accurate diagnosis of malaria is key to effective rational malaria therapy, it has been the most neglected area of Malaria research. Thick blood film microscopy, Blood rapid diagnostic test (bRDT) and Urine Malaria Test (UMT) was comparatively used to study malaria pr...

Open access Research Article 10.9734/AJRIMPS/2018/35788

Determinants of Self-medication of Children by Their Parents at Kisangani

B. G. Mande, K. E. Tebandite, R. Marini & O. Alworonga · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aims: To describe features of self-medication of children and determine factors associated with it. Study Design: This was a cross-sectional study. Place and Duration of Study: This study was conducted in five hospitals of Kisangani, in the Democratic Republic of Congo.  Methodol...

Open access Research Article 10.9734/AJRIMPS/2018/41206

Phytochemical and Structure Elucidation of Stigmasterol from the Stem Bark of Pseudocedrela kotschyi (Harms) (Meliaceae)

V. Atinga, A. Ahmed, H. Nuhu, E. A. Ayeni & G. Dauda · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aim: To perform phytochemical screening, isolate and characterize components from the n-hexane extract of Pseudocedrela kotschyi stem bark. Methodology: The stem bark of P. kotschyi was collected, prepared and exhaustively extracted using analytical graded n-hexane and phytochemi...

Open access Research Article 10.9734/AJRIMPS/2018/42351

Efficacy of Ceftriaxone+Sulbactam+EDTA Combination for Complicated Urinary Tract Infection Patients: A Retrospective Case Series

Reema Kashiva, Dileep Mane & Danish Memon · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: In India, antimicrobial resistance (AMR) remains a major challenge for treatment of infectious diseases mainly due to inappropriate and high consumption of antibiotics. Judicious choice of antibiotics and its optimistic utilization can be one of the potent ways to con...

Open access Research Article 10.9734/AJRIMPS/2018/41914

Clinical Profile of Hypoglycemia in Diabetic Patients: A Prospective Study in a Tertiary Care Hospital

Pankaj Seth, Amit Bery & Arun Kumar Gupta · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: Hypoglycemia refers to a clinical condition resulting from an abnormally low plasma glucose level <40 mg/dl without symptoms and <50 mg/dl with symptoms. Clinically, it is characterized by varying degree of neurological dysfunction and is responsive to the admin...

Open access Research Article 10.9734/AJRIMPS/2018/41645

Advanced Glycation Endproducts, (AGEs): Formation, Complication and Pharmacological Evaluation to Its Inhibition

Mohammad Nadeem Khan & Ragini Gothawal · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Glycation commonly known as non-enzymatic glycosylation is the result of sugar molecules binding with a protein or lipid molecule without controlling the action of an enzyme. During the process of glycation, early stage glycation compounds are formed first, which subsequently rea...

Open access Research Article 10.9734/AJRIMPS/2018/40927

Preliminary Assessments and Renoprotective Effects of Methanol Extract of Parquetina nigrescens (African Parquetina) in Diabetic Wistar Rats

O. I. Adeyomoye & E. O. Adewoye · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aim: Phytochemical screening, toxicity and renoprotective effects of methanol extract of Parquetina nigrescens (MEPN) in diabetic Wistar rats were investigated. Methods: Twenty-five rats divided into five groups (n=5) were used for this study. Groups 1 and 2 served as normal cont...

Open access Research Article 10.9734/AJRIMPS/2018/41737

The Assessment of Muscle Relaxation and Anesthesia Depth in Morbidly Obese Patients: Should We Determine Drug doses According to Lean Body Weight (LBW)?

Naciye Ceyda Demir, Nilgün Kavrut Ozturk, Ilkay Bayar, Bilge Karsli & Kerem Inanoğlu · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: To give a good planned anesthesia to a morbidly obese patient, it is better to have knowledge about morbid obesity’s interaction and impact on drug dosages. For safe drug dosing, not only increased body weight and changed body composition but also physiological change...

Open access Research Article 10.9734/AJRIMPS/2018/41734

A Comparative Analysis of Patients’ Medicine Price in a Public Tertiary Hospital and Private Retail Community Pharmacy in a Rural Nigerian Community

Roland Nnaemeka Okoro & Chijioke Nmeka · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: One-third of the world’s population lacks access to essential medicines and price of medicine is considered one of the most important obstacles to access. Improving access to quality medicines and treatment is currently the most important strategy to reduce disability...

Open access Research Article 10.9734/AJRIMPS/2018/41764