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All published articles 100

Comparative Study between Anthracycline Based Regimen and Taxane Based Regimen in Metastatic Gastric Cancer

Abeer Ibrahim, Mohamed A. Salem & Ahmed Hefny · Journal of Cancer and Tumor International · 2017

Introduction: Taxanes and anthracyclin containing regimes are the most successful regimens in advanced gastric cancer with comparable results but with different toxicity profiles. Objective: To compare efficacy and toxicity of 2 regimens one containing anthrathycline (ECSF regime...

Open access Research Article 10.9734/JCTI/2017/32058

Factors Contributing to Delayed Breast Cancer Presentation: A Prospective Study at Parirenyatwa Group of Hospitals, Harare, Zimbabwe 2010-2013

D. Muchuweti, G. Nyandoro, E. G. Muguti & T. Muchaziwepi · Journal of Cancer and Tumor International · 2017

Background: Breast cancer is one of the most common female cancers in Zimbabwe. A considerable proportion of patients delay presentation, leading to high morbidity and mortality. Delay in presentation can either be provider or patient delay. Survival is related to the stage at pr...

Open access Research Article 10.9734/JCTI/2017/29757

Immunohistochemical Pattern of Breast Cancer in Maiduguri, Borno State

B. A. Imam, O. O. Okechi, K. Abdullahi, U. Abubakar, A. B. Musa, N. Okorie, S. Umar, A. O. Muhammed, O. M. Mohammed, A. Zakariya, K. K. Ibrahim & A. Umar · Journal of Cancer and Tumor International · 2017

Background: Breast cancer is one of the most common cancer affecting women in Nigeria, with a very high morbidity and mortality rate if the diagnosis is delayed. It is common among women in both developed and developing countries of the world. Objectives: This is carried out to d...

Open access Research Article 10.9734/JCTI/2017/31831

Angiotensin II Type 2 Receptor: A Novel Modulator of Inflammation in Pancreatic Ductal Adenocarcinoma through Regulation of NF-ΚB Activity

Ankit V. Gandhi, Galina `Chipitsyna, Daniel Relles, Charles J. Yeo & Hwyda A. Arafat · Journal of Cancer and Tumor International · 2017

Aims: The aim of this study was to explore potential pro-inflammatory, pro-migratory and pro-invasive roles of angiotensin II type 2 receptor (AT2R) in pancreatic ductal adenocarcinoma (PDAC) cells. Study Design: AT2R-specific agonist (CGP42112A, CGP), blocking antibody, or siRNA...

Open access Research Article 10.9734/JCTI/2017/31326

Histo-Epidemiology of Kidney Cancer in Cameroon: About 110 Cases

Jean Paul Ndamba Engbang, Beyeme Sala, Celestin Fonkwa, Yoan Ligan, Bruno Djougmo Djimeli, Godefroy Simo, André Moune, Amadou Fewou, Jean Louis Oyono Essame, Alan Hasigov & Aleksandre Ephiev · Journal of Cancer and Tumor International · 2016

Objectives: To describe the epidemiological and histopathological aspects of kidney cancer in Cameroon. Materials and Methods: This was a descriptive retrospective study on malignant tumors of the kidney examined in the anatomical pathology laboratories of five regions (Center, L...

Open access Research Article 10.9734/JCTI/2017/30063

Complex of Small Non-coding RNAs piR-30074 and Antago-miR-155 and miR-125b with DDMC Carrier Transforms Girardi Heart Cells into CD4+ Cells

Oxana V. Klimenko · Journal of Cancer and Tumor International · 2016

Girardi heart cells are cell culture of right atrial cells contaminated with HeLa cervical adenocarcinoma cells. The combined cells have genotypic characteristics of cervical cancer. In this study, was investigated influence of complex of DDMC vector with small non-coding RNAs (s...

Open access Research Article 10.9734/JCTI/2016/30472

Bilateral Breast Fibromatosis in a 41 Years Old Woman

Amadou Fewou, Jean Paul Engbang, George Enoh Orock, Jean Marie Mendimi Nkodo, Clarisse Kabiyéné & Jean Louis Essame Oyono · Journal of Cancer and Tumor International · 2016

Breast fibromatosis is a rare benign tumor of soft tissues with local spread, frequently recurrent but with no metastatic evolutions. We present a case diagnosed in a 41 years old patient referred to a Douala private medical center in February 2012, presenting bilateral breast tu...

Open access Research Article 10.9734/JCTI/2016/30357

Long Time Survival in Small Cell Carcinoma of the Bladder: A Case Report

C. Assenmacher, A. Roosendaal & C. Salembier · Journal of Cancer and Tumor International · 2016

Small cell carcinoma of the bladder only accounts for 0,35 – 1% of all bladder cancers. It is a rare, but aggressive tumor. As for other types of bladder cancer, first symptoms are most often painless hematuria [1,2]. The clinical presentation does not differ from other bladder c...

Open access Research Article 10.9734/JCTI/2016/29876

Evolutionary Basis of Cancer Metastasis and Its Implication to a Lasting Cure

Emmanuel O. Adesuyi, Doubra A. Obaila & Mojisola A. Aladeyelu · Journal of Cancer and Tumor International · 2016

This review is intended to take us through a journey on how cancer had been treated and highlight the paradigm shift in understanding its treatment since adoption of evolution concept and hope to point to a possible future breakthrough in cancer management. Researchers estimate t...

Open access Research Article 10.9734/JCTI/2016/27710

Association of Activated Partial Thromboplastin Time and Fibrinogen Level in Patients with Polycythemia Vera

Sahar Elbager, Samah Abd Alla, Tahani Mursal & Amar A. Dowd · Journal of Cancer and Tumor International · 2016

Aims: To evaluate the Activated Partial Thromboplastin Time (APTT) and fibrinogen levels in patients with Polycythemia vera (PV). Study Design: Analytical, laboratory, hospital-based, cross sectional study. Place and Duration of Study: Hematology clinic at Fedail hospital Khartou...

Open access Research Article 10.9734/JCTI/2016/29678

Role of Oncogenes and Tumor Suppressors in Metabolic Reprogramming and Cancer Therapeutics: A Review

Muhammad Azharuddin & David Sharon · Journal of Cancer and Tumor International · 2016

Recently there has been a renewed interest on the signaling pathways and metabolic changes in cancer cells. It is well known that there are several oncogenes and tumor suppressors that affect cancer metabolism and re-engineer it for better growth and survival. The best descriptio...

Open access Research Article 10.9734/JCTI/2016/29641

Analysis of Pelvic Lymph Nodal Metastasis in Operable Cases of Cancer Cervix-A One Year Cohort Study at a Regional Cancer Centre

Ashok Kumar Padhy, V. Abarajda, Rohani Nayak, B. L. Nayak, J. Mohapatra & Sgarika Samantaray · Journal of Cancer and Tumor International · 2016

Objective: To study the incidence of nodal metastasis in early stage operable cases of  cancer cervix and to correlate the nodal metastasis with different parameters like stage, degree of differentiation, lympho-vascular space invasion (LVSI) and deep stromal invasion. Materials...

Open access Research Article 10.9734/JCTI/2016/29494

Assessment of Survivin and Lactate Dehydrogenase Isoenzyme in Leukemic Egyptian Patients

Fahmy T. Ali, Eman M. Abd El Azeem, Ahmed A. Shams El Din & Mohammed H. Youssif · Journal of Cancer and Tumor International · 2016

Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers is carried out in order to quickly identify tumor cells and predict treatment response, ultimately leading to a favorable thera...

Open access Research Article 10.9734/JCTI/2016/28234

Primary Breast Lymphoma: A Study of 9 Cases

Olfa El Amine, Kmira Zahra, Azza Gabsi, Aida Goucha, Jamel Ben Hassouna, Khaled Rahal & Amor Gamoudi · Journal of Cancer and Tumor International · 2016

Aim: Non-Hodgkin's primary lymphoma of the breast is rare. These tumors represent 0.04 to 0.52% of malignant breast pathology, 2.2% of extranodal lymphoma and 0.4% of all non-Hodgkin’s lymphoma. Clinical and radiological aspects show no special characteristics. The aim of our stu...

Open access Research Article 10.9734/JCTI/2016/28910

Significance of Tumor Marker CA15-3 in Metastatic Breast Cancer

Hoor Fatima, Amir Maqbool, Marium Siddiqui, Ghulam Haider, Habiba Sohail, Omema Saleem & Afarina Ahmed · Journal of Cancer and Tumor International · 2016

Secondary spread of cancer to bones is commonest and frequent phenomenon and enhances the need of special care for sufferers. Bone metastases mostly are the first complication of different variety of cancers which increase the need of care and expensive facilities. Blood dissemin...

Open access Research Article 10.9734/JCTI/2016/28440