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All published articles 581

Exploring the Role of Probiotics and Antioxidants in Potentiating the Efficacy of Citalopram Hydrobromide for Depression Therapy: A Preclinical Study in Swiss Albino Mice Model

Siddharth Kamble, Anirudha Kadam, Srinivas Bhairy, Ravi Wanare & Rajesh Mandade · International Neuropsychiatric Disease Journal · 2025

Background and objective: Depression is a leading cause of disability worldwide, characterized by mood disturbances and neurobiological alterations. The gut–brain axis and oxidative stress have emerged as critical factors in its pathophysiology. Probiotics, through microbiome mod...

Open access Research Article 10.9734/indj/2025/v22i5513

Synthetic Xanthone Derivatives as Multifunctional Therapeutics for Alzheimer’s Disease: Chemistry, Mechanisms and Future Perspectives

Kanchan Ghatge, Kavita Patil, Akshada Devendra Khetre, Vrushabh Patil & Ramling Mali · International Neuropsychiatric Disease Journal · 2025

Introduction: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss, with limited effective therapeutic options available. Synthetic xanthone derivatives have recently garnered attention due to their diverse pharma...

Open access Research Article 10.9734/indj/2025/v22i5512

Assessment of Psychological Well-being among Residents of Ilobu, Erin-Osun and Ifon-Osun in Osun State, Nigeria

Olawale Sunday Asabi, Henry O. Sawyerr, Opasola O. A & Adiama B.Y · International Neuropsychiatric Disease Journal · 2025

Background: Housing conditions are increasingly recognised as key social determinants of mental health, yet evidence from semi-urban Nigeria remains sparse. Objective: To quantify the prevalence and predictors of psychological well-being among adult residents of Ilobu, Erin-Osun...

Open access Research Article 10.9734/indj/2025/v22i5511

Awareness of Chronic Migraine Diagnosis and Management among Primary Care Physicians in PSMMC in Riyadh

Abdullah Ahmad Aleidan, Mostafa Kofi, Ghada Alarfaj, Abdulaziz Abdulrahman Ali Alquraishi, Abdulrahman Mohammed Alshathri & Faisal Hisham Almedimegh · International Neuropsychiatric Disease Journal · 2025

Background: Chronic migraine (CM) is a disabling neurological disorder frequently underdiagnosed and undertreated in primary care, despite its high prevalence and burden on patients and healthcare systems. Primary care physicians (PCPs) are the frontline providers for headache ma...

Open access Research Article 10.9734/indj/2025/v22i5510

Sports Betting Expansion in Brazil: Impacts on Psychiatric Health

Luiz Fernando Costa Campos & Marcelo Ferreira Caixeta · International Neuropsychiatric Disease Journal · 2025

This article presents a psychiatric analysis of the rapid growth of online betting (bets) in Brazil and its connections to the political structure of the country. Current data indicate that approximately 30% of Brazilians, mainly young men, have engaged in online bets, with alarm...

Open access Research Article 10.9734/indj/2025/v22i5509

Mental Health Literacy among Medical Students in Zanzibar: A Cross-Sectional Assessment

Rodolfo Isidro Bosch Bayard, Kenechukwu M. Okafor, Chukwum J. Okafor, Diane Millo Martin, Othman Said Abdalla, Lorena Bosch Orihuela, Aniuska Palacios Noa & Emmanuel I. Obeagu · International Neuropsychiatric Disease Journal · 2025

Introduction: Mental illness poses a significant global health burden. Medical students, as future healthcare providers, play a crucial role in mental health service delivery, making their knowledge and attitudes toward mental illness essential for improving healthcare outcomes....

Open access Research Article 10.9734/indj/2025/v22i4508

Migration and Mental Health: A Review of Students in the United Kingdom

Omotola Raliat Atiba, Bilkisu Musa & Anuoluwapo Oyawale · International Neuropsychiatric Disease Journal · 2025

Migration for educational purposes has become a defining feature of global higher education systems, with several universities in the global north, including the United Kingdom (UK), accounting for millions of students who migrate across borders to pursue academic qualifications...

Open access Research Article 10.9734/indj/2025/v22i4507

Prevalence of Posttraumatic Stress Disorder and Its Impact on the Daily Lives of Schoolchildren in Public Schools in Morocco: A Cross-sectional Study

Khalid Astitene · International Neuropsychiatric Disease Journal · 2025

Posttraumatic stress disorder (PTSD) usually occurs after traumatic occurrences that exceed the range of common human experience. The study investigates the prevalence of PTSD among schoolchildren in public schools in the city of Salé in Morocco. Our seconde objective for this st...

Open access Research Article 10.9734/indj/2025/v22i4506

Prevalence of Postpartum Anxiety and Depression among Postpartum Mothers: A Study at Postnatal Clinics in Enugu and Delta States, Nigeria

Arinze Queen U., Swetha Manoj, Onu S. Ngozi, Chiamaka Goodness Ujam, Darlyn .C. Ogbusu, Obasi Fortune . A., Ojeh F. Golden, Okonkwo Chukwuebuka . I., Eziechi E. Sandra, Katerina Paraskevas, Adetokunbo O. Priscilla, Prakrut Sethi, Theophilus Saudje, Okenwa D. Ada, Lawal Habiba & Akhaine J. Precious · International Neuropsychiatric Disease Journal · 2025

Introduction: Postpartum depression and anxiety are critical maternal mental health issues, especially in low- and middle-income countries like Nigeria, where mental health services are limited. These conditions can harm both mothers and their children and are often undiagnosed a...

Open access Research Article 10.9734/indj/2025/v22i4505

Screen Time and Headaches among Undergraduate Adolescents in Rivers State: A Menace of the Digital Epoch

Gabriel-Job Nneka & Wobo Kininyiruchi N · International Neuropsychiatric Disease Journal · 2025

Background: The widespread use of digital technologies has led to increased screen exposure among adolescents, raising concerns about their potential health implications. Prolonged screen time has been associated with various adverse outcomes, including obesity, problems with cog...

Open access Research Article 10.9734/indj/2025/v22i4504

The Prospect of Hypertension and Diabetes among Saudi Healthcare Nightshift Workers

Khawla Mohammed Salih Elbasheri Jadkareem & Hussain Gadelkarim Ahmed · International Neuropsychiatric Disease Journal · 2025

Background: Night shift employment is linked to various health consequences, especially among healthcare professionals. This study aims to evaluate the prevalent chronic illnesses among medical personnel working extended night shifts in Saudi Arabia. Methodology: This study was a...

Open access Research Article 10.9734/indj/2025/v22i4503

Development and Validation of the International Index of Erectile Function (IIEF) in Bangla-speaking Population

Muhammad Kabir Hasan Parvez, Mohammad Ashraful Siddiqui Pathan, Dil Mohammad Sazzadul Kabir Sabuz, Md. Asif Nowaz, Md. Enamul Hoque Khan, Md. Tanvir Rahman Shah, MMA Shalahuddin Qusar Biplob, Mohammad Sohel Al Mozahid, Md. Sazib Mian & Asaduzzaman Laskar · International Neuropsychiatric Disease Journal · 2025

Background: Erectile disorder affects about 15% of men globally, with higher prevalence in developing countries. Effective assessment requires a standardized tool, but Bangladesh lacks a validated one. The International Index of Erectile Function (IIEF) is widely used to measure...

Open access Research Article 10.9734/indj/2025/v22i4502

Attitudes and Stigma toward Dementia among Medical and Environmental Health Students at the School of Health and Medical Sciences at the State University of Zanzibar

Rodolfo Isidro Bosch Bayard, Chukwum J. Okafor, Diane Millo Martin, Nahra A. Selemani, Fatma A. Mohamed, Yasini S. Hamisi, E. N Adejumo, Seyi Samson Enitan & Lorena Bosch Orihuela · International Neuropsychiatric Disease Journal · 2025

Introduction: Public stigma involves negative stereotypes of dementia patients as burdensome, leading to social distancing, while self-stigma refers to individuals with dementia internalizing these views, affecting their mental well-being. Structural stigma encompasses systemic b...

Open access Research Article 10.9734/indj/2025/v22i4501

Kelch-like ECH-associated Protein 1-nuclear Factor Erythroid 2-related Factor 2 Pathway Activation in Neuroprotection and Cognitive Enhancement

Onoriode Andrew Udi & Charles German Ikimi · International Neuropsychiatric Disease Journal · 2025

Neurodegenerative diseases and cognitive decline pose significant global health challenges. The Kelch-like ECH-associated protein 1 (Keap1) – nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is a master regulator of cellular defense against oxidative stress and inflamma...

Open access Research Article 10.9734/indj/2025/v22i4500

Artificial Intelligence in Mental Health: Detecting Depression and Anxiety Using Social Media Data

Daniel M. Mami & Teo Rong Xuan · International Neuropsychiatric Disease Journal · 2025

Mental health problems, including sadness and anxiety, have become important public health issues that affect more than 280 million people around the world. For treatment to work, it is important to diagnose problems early and start treatment right once. Unfortunately, standard t...

Open access Research Article 10.9734/indj/2025/v22i4499