Synthetic Organic Molecules as Metallic Corrosion Inhibitors: General Aspects and Trends
Organics · pp. 232–250 · Published 17 May 2023
10.3390/org4020019Abstract
Organic molecules are gaining special attention over the last years in the corrosion area thanks to their general low achievable cytotoxicity, structural versatility, and environmentally friendly obtainment methods. Under those approaches, synthetic organic motifs have attracted the interest of researchers due to their variated methods of obtention through molecular manipulation via diverse chemical reactions, allowing the production of adequately planned structures or repurposing their original application in the case of drugs. This review summarizes general aspects that are desired in organic molecules as corrosion inhibitors, presenting selected works published in the 2022–2023 period and emphasizing the importance of finding novel and different organic corrosion inhibitors. Patents were not considered in this review. Scifinder, Google Scholar, and Web of Science were employed as databases. Mathematical and analytical methods involved in the search for corrosion inhibitors are out of this review’s scope.
References (85)
- 1 Aslam, 2022, Corrosion Inhibition of Steel Using Different Families of Organic Compounds: Past and Present Progress [DOI]
- 2 Popoola, 2019, Organic Green Corrosion Inhibitors (OGCIs): A Critical Review [DOI]
- 3 Quraishi, 2021, Development of Environmentally Benign Corrosion Inhibitors for Organic Acid Environments for Oil-Gas Industry [DOI]
- 4 Lou, 2021, Microbiologically Influenced Corrosion Inhibition Mechanisms in Corrosion Protection: A Review [DOI]
- 5 Wei, 2020, Green Inhibitors for Steel Corrosion in Acidic Environment: State of Art [DOI]
- 6 Kokalj, 2022, Corrosion Inhibitors: Physisorbed or Chemisorbed? [DOI]
- 7 Verma, 2022, Electronic Effect vs. Molecular Size Effect: Experimental and Computational Based Designing of Potential Corrosion Inhibitors [DOI]
- 8 Chauhan, 2021, Molecular Structural Aspects of Organic Corrosion Inhibitors: Experimental and Computational Insights [DOI]
- 9 Fateh, 2020, Review of Corrosive Environments for Copper and Its Corrosion Inhibitors [DOI]
- 10 Quattrociocchi, 2020, Quantum chemical properties using the DFT method: A theoretical tool applied in the study of corrosion inhibitors
- 11 Quattrociocchi, 2022, Técnicas Experimentais e Teóricas Aplicadas Ao Estudo de Inibidores Orgânicos de Corrosão Em Meio Ácido [DOI]
- 12 Kokalj, 2021, On the Alleged Importance of the Molecular Electron-Donating Ability and the HOMO–LUMO Gap in Corrosion Inhibition Studies [DOI]
- 13 Kokalj, 2021, Molecular Modeling of Organic Corrosion Inhibitors: Calculations, Pitfalls, and Conceptualization of Molecule–Surface Bonding [DOI]
- 14 Verma, 2021, Computational Modeling: Theoretical Predictive Tools for Designing of Potential Organic Corrosion Inhibitors [DOI]
- 15 Kokalj, A., and Costa, D. (2018). Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry, Elsevier.
- 16 Verma, C., Ebenso, E.E., and Quraishi, M.A. (2021). Environmentally Sustainable Corrosion Inhibitors: Fundamentals and Industrial Applications, Elsevier.
- 17 Dewangan, A.K., Dewangan, Y., Verma, D.K., and Verma, C. (2022). Environmentally Sustainable Corrosion Inhibitors: Fundamentals and Industrial Applications, Elsevier. [DOI]
- 18 Fernandes, 2019, Green Synthesis of 1-Benzyl-4-Phenyl-1H-1,2,3-Triazole, Its Application as Corrosion Inhibitor for Mild Steel in Acidic Medium and New Approach of Classical Electrochemical Analyses [DOI]
- 19 Ebenso, 2021, Molecular modelling of compounds used for corrosion inhibition studies: A review [DOI]
- 20 Sanyal, 1981, Organic compounds as corrosion inhibitors in different environments—A Review [DOI]
- 21 Samiee, 2019, Assessment of the Smart Self-Healing Corrosion Protection Properties of a Water-Base Hybrid Organo-Silane Film Combined with Non-Toxic Organic/Inorganic Environmentally Friendly Corrosion Inhibitors on Mild Steel [DOI]
- 22 Mu, 2006, Molybdate and Tungstate as Corrosion Inhibitors for Cold Rolling Steel in Hydrochloric Acid Solution [DOI]
- 23 Raja, 2016, Reviews on Corrosion Inhibitors: A Short View [DOI]
- 24 Gece, 2011, Drugs: A Review of Promising Novel Corrosion Inhibitors [DOI]
- 25 Iroha, 2021, Experimental, Adsorption, Quantum Chemical and Molecular Dynamics Simulation Studies on the Corrosion Inhibition Performance of Vincamine on J55 Steel in Acidic Medium [DOI]
- 26 Shukla, 2009, Streptomycin: A Commercially Available Drug as Corrosion Inhibitor for Mild Steel in Hydrochloric Acid Solution [DOI]
- 27 Eddy, 2009, Inhibition of the Corrosion of Mild Steel in H2SO4 by Penicillin G
- 28 Ituen, 2016, Eco-friendly corrosion inhibitor from Pennisetum purpureum biomass and synergistic intensifiers for mild steel [DOI]
- 29 Rajeswari, 2013, Physicochemical Studies of Glucose, Gellan Gum, and Hydroxypropyl Cellulose—Inhibition of Cast Iron Corrosion [DOI]
- 30 Wang, 2022, Sunflower-head extract as a sustainable and eco-friendly corrosion inhibitor for carbon steel in hydrochloric acid and sulfuric acid solutions [DOI]
- 31 Wang, 2022, Insight into the anti–corrosion behavior of Reineckia Carnea leaves extract as an eco–friendly and high–efficiency corrosion inhibitor [DOI]
- 32 Nazari, 2023, Application of green active bio-molecules from the aquatic extract of Mint leaves for steel corrosion control in hydrochloric acid (1M) solution: Surface, electrochemical, and theoretical explorations [DOI]
- 33 Haque, 2020, Electrochemical and Surface Studies on Chemically Modified Glucose Derivatives as Environmentally Benign Corrosion Inhibitors [DOI]
- 34 Chaubey, 2021, Frontiers and Advances in Green and Sustainable Inhibitors for Corrosion Applications: A Critical Review [DOI]
- 35 Kumar, 2022, Natural gums as corrosion inhibitor: A review [DOI]
- 36 Quaraishi, 2001, A review on macrocyclics as corrosion inhibitors [DOI]
- 37 Wight, 1960, Some Reactions of Mannich Bases Derived from a-Phenoxyacetophenone and a-Phenoxypropiophenone [DOI]
- 38 Tramontini, 1973, Advances in the Chemistry of Mannich Bases [DOI]
- 39 Roman, 2015, Mannich bases in medicinal chemistry and drug design [DOI]
- 40 Tramontini, 1988, Mannich bases in polymer chemistry [DOI]
- 41 Zhang, 2022, Bis-Mannich Bases as Effective Corrosion Inhibitors for N80 Steel in 15% HCl Medium [DOI]
- 42 Schaub, 2021, Efficient Industrial Organic Synthesis and the Principles of Green Chemistry [DOI]
- 43 Anastas, 2010, Green Chemistry: Principles and Practice [DOI]
- 44 Fernandes, 2022, Innovative Characterization of Original Green Vanillin-Derived Schiff Bases as Corrosion Inhibitors by a Synergic Approach Based on Electrochemistry, Microstructure, and Computational Analyses [DOI]
- 45 Zinad, 2021, Comparative Investigations of the Corrosion Inhibition Efficiency of a 1-Phenyl-2-(1-Phenylethylidene)Hydrazine and Its Analog Against Mild Steel Corrosion in Hydrochloric Acid Solution
- 46 Selatnia, 2023, Exploring the Feasibility of New Eco-Friendly Heterocyclic Compounds for Establishing Efficient Corrosion Protection for N80 Steel in a Simulated Oil Well Acidizing Environment: From Molecular-Level Prediction to Experimental Validation [DOI]
- 47 Yakan, 2022, New N,N′-Bis(Thioamido)Thiocarbohydrazones and Carbohydrazones: Synthesis, Structure Characterization, Antioxidant Activity, Corrosion Inhibitors and DFT Studies [DOI]
- 48 Bimoussa, 2022, Synthesis, Experimental and Theoretical Studies of Sesquiterpenic Thiosemicarbazone and Semicarbazone as Organic Corrosion Inhibitors for Stainless Steel 321 in H2SO4 1M [DOI]
- 49 Mehta, 2022, Studies on Pyrimidine Derivative as Green Corrosion Inhibitor in Acidic Environment: Electrochemical and Computational Approach [DOI]
- 50 Rezaeivala, 2022, Experimental and Theoretical Investigation of Corrosion Inhibition Effect of Two Piperazine-Based Ligands on Carbon Steel in Acidic Media [DOI]
- 51 Lessa, 2021, 1,2,3-Triazole Nucleus as a Versatile Tool for the Obtainment of Novel Biologically Active Compounds: An Overview [DOI]
- 52 Sahiba, 2020, Saturated Five-Membered Thiazolidines and Their Derivatives: From Synthesis to Biological Applications [DOI]
- 53 Grunberg, 1973, Properties of Heterocyclic Compounds: Monocyclic compounds with five-membered rings [DOI]
- 54 Ambhaikar, 2023, Five-membered ring systems: With N and S atom [DOI]
- 55 Kotian, 2020, Small Molecule Based Five-Membered Heterocycles: A View of Liquid Crystalline Properties beyond the Biological Applications [DOI]
- 56 Filho, 2023, Synthesis, Biological Activity and Applications of 1,2,5-Oxadiazol: A Brief Review [DOI]
- 57 Ouakki, 2022, Imidazole Derivatives as Efficient and Potential Class of Corrosion Inhibitors for Metals and Alloys in Aqueous Electrolytes: A Review [DOI]
- 58 Hou, 2022, Synthesis of Three Imidazole Derivatives and Corrosion Inhibition Performance for Copper [DOI]
- 59 Cherrak, 2022, Performance Evaluation of Newly Synthetized Bi-Pyrazole Derivatives as Corrosion Inhibitors for Mild Steel in Acid Environment [DOI]
- 60 Li, 2022, Insights into Triazole Derivatives as Potential Corrosion Inhibitors in CMP Process: Experimental Evaluation and Theoretical Analysis [DOI]
- 61 Hrimla, M., Bahsis, L., Laamari, M.R., Julve, M., and Stiriba, S.E. (2022). An Overview on the Performance of 1,2,3-Triazole Derivatives as Corrosion Inhibitors for Metal Surfaces. Int. J. Mol. Sci., 23. [DOI]
- 62 Abdelsalam, 2022, Green Synthesis, Electrochemical, and DFT Studies on the Corrosion Inhibition of Steel by Some Novel Triazole Schiff Base Derivatives in Hydrochloric Acid Solution [DOI]
- 63 Arrousse, 2022, Thiophene Derivatives as Corrosion Inhibitors for 2024-T3 Aluminum Alloy in Hydrochloric Acid Medium [DOI]
- 64 Kumar, 2022, Newly Synthesized Oxadiazole Derivatives as Corrosion Inhibitors for Mild Steel in Acidic Medium: Experimental and Theoretical Approaches [DOI]
- 65 Mathada, 2023, The Multi-Pharmacological Targeted Role of Indole and its Derivatives: A review [DOI]
- 66 Li, 2022, Recent Progress of Bioactivities, Mechanisms of Action, Total Synthesis, Structural Modifications and Structure-activity Relationships of Indole Derivatives: A Review [DOI]
- 67 Yan, 2010, A Novel Water-Soluble Gossypol Derivative Increases Chemotherapeutic Sensitivity and Promotes Growth Inhibition in Colon Cancer [DOI]
- 68 Berdimurodov, 2022, Novel Gossypol–Indole Modification as a Green Corrosion Inhibitor for Low–Carbon Steel in Aggressive Alkaline–Saline Solution [DOI]
- 69 Ajani, 2022, Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs—A review [DOI]
- 70 Rajendran, 2022, Friedländer’s synthesis of quinolines as a pivotal step in the development of bioactive heterocyclic derivatives in the current era of medicinal chemistry [DOI]
- 71 Benhiba, 2022, Bisquinoline Analogs as Corrosion Inhibitors for Carbon Steel in Acidic Electrolyte: Experimental, DFT, and Molecular Dynamics Simulation Approaches [DOI]
- 72 Elaryian, 2022, Synthesis, Characterization of Novel Coumarin Dyes as Corrosion Inhibitors for Mild Steel in Acidic Environment: Experimental, Theoretical, and Biological Studies [DOI]
- 73 Caihong, 2022, Novel Nitrogen Based Heterocyclic Compound as Q235 Steel Corrosion Inhibitor in 15% HCl under Dynamic Condition: A Detailed Experimental and Surface Analysis [DOI]
- 74 Ramesh, 2020, Innovative Green Synthesis of 4-Aryl-Pyrazolo[5,6]Pyrano [2,3-d]Pyrimidines under Catalyst-Free Conditions [DOI]
- 75 Ramachandran, 2022, Structural and Electronic Impacts on Corrosion Inhibition Activity of Novel Heterocyclic Carboxamides Derivatives on Mild Steel in 1 M HCl Environment: Experimental and Theoretical Approaches [DOI]
- 76 Elqars, 2022, New 3-(2-Methoxyphenyl)-Isoxazole-Carvone: Synthesis, Spectroscopic Characterization, and Prevention of Carbon Steel Corrosion in Hydrochloric Acid [DOI]
- 77 Elqars, 2022, Synthesis, Spectroscopic Characterization, and Prevention of Carbon Steel Corrosion in Hydrochloric Acid of a New Bis-Isoxazoline-Carvone [DOI]
- 78 Geng, 2022, Rosin Imidazoline as an Eco-Friendly Corrosion Inhibitor for the Carbon Steel in CO2-Containing Solution and Its Synergistic Effect with Thiourea [DOI]
- 79 Akinyele, 2022, Synthesis and Corrosion Inhibition Studies of (E)-3-(2-(4-chloro-2-Nitrophenyl)Diazenyl)-1-Nitrosonaphthalen-2-Ol on Mild Steel Dissolution in 0.5 M HCl Solution- Experimental, DFT and Monte Carlo Simulations [DOI]
- 80 Shaaban, 2022, Novel Organoselenium-Based N-Mealanilic Acids as Efficacious Corrosion Inhibitors for 6061 Aluminum Alloy in Molar HCl: In-Silico Modeling, Electrochemical, and Surface Morphology Studies [DOI]
- 81 Shaaban, 2021, Synthesis, experimental, and computational studies of water soluble anthranilic organoselenium compounds as safe corrosion inhibitors for J55 pipeline steel in acidic oilfield formation water [DOI]
- 82 Furtado, 2022, Green Eugenol Oligomers as Corrosion Inhibitors for Carbon Steel in 1M HCl [DOI]
- 83 Rahimi, 2022, Novel Sucrose Derivative as a Thermally Stable Inhibitor for Mild Steel Corrosion in 15% HCl Medium: An Experimental and Computational Study [DOI]
- 84 Damej, 2022, Inhibition Effect of N-Propargyl Saccharin as Corrosion Inhibitor of C38 Steel in 1 M HCl, Experimental and Theoretical Study [DOI]
- 85 Ruf, E., Naundorf, T., Seddig, T., Kipphardt, H., and Maison, W. (2022). Natural Product-Derived Phosphonic Acids as Corrosion Inhibitors for Iron and Steel. Molecules, 27. [DOI]
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