Interstitial Nephritis as the Initial Presentation of Sjogren’s Syndrome: A Case Report with Review of Literature

Abstract

Primary Sjögren’s syndrome is a rare autoimmune condition affecting the exocrine glands. However, extra-glandular manifestations are not uncommon and may present as the initial symptoms of this disorder. Such cases offer a great challenge to clinicians. Here we present a case of primary Sjögren’s syndrome, which presented with incidentally detected renal dysfunction which on investigation revealed distal renal tubular acidosis and tubulointerstitial nephritis. The patient responded to combined therapy of steroid and rituximab and is currently having a stable renal function.