Understanding Benefits of Curcumin on Cognitive Function from Molecular Aspect: A Review
A. A. A. Putri Laksmidewi, Richard Suherlim
Asian Journal of Medicine and Health · pp. 1–7 · Published 30 Jun 2021
10.9734/ajmah/2021/v19i730340Abstract
Cognitive function has a significant impact on individuals’ quality of life. Over time, human cognitive function tends to decline. The importance of cognitive function in everyday life has led many researchers to seek alternative treatments to maintain and improve cognitive function. Some studies show that curcumin can improve cognitive function and prevent cognitive decline in humans. This review focuses on the benefits of curcumin on cognitive function and the mechanism of how it works from molecular aspect. According to some studies, one of the factors leading to cognitive decline is chronic low-grade systemic inflammation. This review will focus on antioxidant, anti-inflammatory, neuroprotective effects, and β amyloid aggregation inhibition properties of curcumin that can improve cognitive function or delay cognitive decline. It is important to understand the basic reasons why curcumin can have benefits on cognitive function, this can be seen from the mechanisms that are reflected in the biomolecular aspect.
References (10)
- 1 Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice [DOI]
- 2 Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial [DOI]
- 3 Molecular mechanisms of curcumin action: Gene expression [DOI]
- 4 The effect of curcumin on cognition in Alzheimer’s disease and healthy aging: A systematic review of pre-clinical and clinical studies [DOI]
- 5 Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults [DOI]
- 6 Cognitive decline in the elderly: an analysis of population heterogeneity [DOI]
- 7 Efficacy of curcumin for age-associated cognitive decline: a narrative review of preclinical and clinical studies [DOI]
- 8 Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China [DOI]
- 9 Curcumin supplementation and motor-cognitive function in healthy middle-aged and older adults [DOI]
- 10 Effects of Curcumin on Cognitive Functioning and Inflammatory State in Schizophrenia [DOI]
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