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Research Article Open access CC BY 4.0

Thyrotoxic Valvulopathy in a 7-year-Old Child: Case Report and Literature Review

Ujunwa FA, Ohuche Ijeoma, Eke CB, Chikani U, Chinawa JM

Cardiology and Angiology: An International Journal · pp. 82–85 · Published 13 Feb 2024

10.9734/ca/2024/v13i1396

Abstract

Introduction: Children with thyrotoxicosis may present rarely with valvulopathies. This disease is a syndrome complex of hyperdynamic status due to systemic manifestation of elevated circulating thyroid hormone levels.  Case Reports: O.C, a 7-year-old female child presented with abdominal pain that started seven days ago, passage of loose stool that started five days ago and weight loss that started five days ago. Salient findings at presentation were tachycardia, anterior neck swelling that moves with swallowing with a grade 3/6 pan-systolic murmur maximal at the apex. A diagnosis of hyperthyroidism at risk of thyrotoxicosis was made based on supported laboratory evidence. Echocardiography done showed severe mitral regurgitation. She is on Tabs Carbimazole and Propranolol. She has improved remarkably and has been on follow up. Conclusion: Hyperthyoidism affects multiple organ systems in the body and the heart is not spared. Most of the cardiac manifestations are functional and occur as a result of the hyperfunctioning gland. A high index of suspicion is required, as many of the patients present with only the consequences of hyperthyroidism.

Valvopathy echocardiography murmurs hyperthyroidism child

References (8)

  1. 1 Cardio-Thyrotoxicosis Syndrome: A Review of Thyrotoxic Cardiovascular Disease [DOI]
  2. 2 Severe Mitral Regurgitation As a Result of Rupture of Mitral Valve Chordae Tendineae in a Patient With Graves Disease [DOI]
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  7. 7 Mitral valve prolapse in adolescent female with hyperthyroidism [DOI]
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