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Theoretical Study of Coordination of Succinimide, of N-hydroxosuccinimide and of Their Deprotonated Forms

Kuevi Urbain Amah, Atohoun Yacolé Guy Sylvain, Kpotin Assongba Gaston, Kpota-Houngue MahougbéTata Alice, Mensah Jean-Baptiste

International Research Journal of Pure and Applied Chemistry · pp. 1–11 · Published 24 Sep 2016

10.9734/IRJPAC/2016/29063

Abstract

Transition metals complexes with a given structure could be alternatives in treatment of some incurable diseases because the coordination of active ingredients modifies deeply the physiological properties of metals and of ligands. This work is a theoretic study of the coordination of succinimide, of N-hydroxosuccinimide and of their depronated forms. The aim of this study was the determination of the more favorable coordination site of each ligand. It was found that the succinimide and N-hydroxosuccinimide form complexes via an imide oxygen atom. The succinimide deprotonated species forms a complex through the nitrogen atom. The deprotonated form of the N-hydroxosuccinimide can form a chelate via an imide oxygen atom and the oxygen atom from hydroxyl group. Calculations have be performed by DFT/B3LYP method in the 6-311g++(d,p) orbital basis set in the Laboratory of theoretical chemistry and Molecular Spectroscopy (LACTHESMO), Abomey-Calavi University between January and June 2016.

Coordination compound succinimide zinc(II) chloride DFT/ B3LYP 6-311G (d,p)

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Rakesh Kumar, Gursharan Singh · Oriental Journal Of Chemistry · 2021

Reactions of MoCl5 and MoO2Cl2 with Succinimide, 1, 4-Diaminobutane, 3-Methylpyridine, 1, 3-Diaminopropane, Pyrazole and 1- Methylpyrrolidine in Tetrahydrofuran

Rakesh Kumar, Gursharan Singh · Oriental Journal Of Chemistry · 2021

Reactions of MoCl5 with 4-Methylpyridine, 2-Methylpyridine and 1-Methylimidazole in Tetrahydrofuran

Rakesh Kumar, Gursharan Singh · Oriental Journal Of Chemistry · 2021

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