The Relationship and Role of Proactive Medicine in Kawasaki Disease and Related Infectious Immunological Diseases

Abstract

Kawasaki Disease (KD) is an acute systemic vasculitis disease that commonly affects children under the age of 5. Its pathogenesis essentially involves a pathological process driven by both infectious factors and immune abnormalities, and it has a core pathological association with infectious immune diseases. This article will analyze the interaction between the two in active medicine from four aspects: their core relationship, supporting mechanism, convergence points, and mutual promotion value. From the perspective of active medicine, this association provides a key target for disease prevention and control. KD is a typical manifestation of the pathological mechanism of infectious immune diseases, and active medicine, by targeting infection prevention, immune regulation, and early intervention, has constructed a full-chain prevention system from risk warning to complication prevention, providing an important paradigm for the clinical management of such immune-mediated diseases. The study concludes that in the active medical system, Kawasaki disease and infection-related immune disorders have a deep binding relationship of "typical subtypes and broad categories, benchmark practices and general theories", and also a classic clinical paradigm of "theory guiding practice and practice feeding back to theory".