The Prevalence Rate of Helicobacter pylori amongst Patients Presenting with Presumptive Gastritis in Rivers State, Nigeria Using Antigen Detection Method

Abstract

Background: Gastritis is an inflammation of the protective lining of the stomach which has been a global burden in the past decades. It can be caused by irritation, excessive alcohol use, chronic vomiting, stress, or the use of certain medications such as aspirin or other anti-inflammatory drugs. It may also be caused by Helicobacter pylori- a gram-negative, microaerophilic, spiral (helical) bacterium usually found in the stomach. Methodology: A cross-sectional, hospital-based study aimed at determining the prevalence rate of Helicobacter pylori amongst patients presenting with presumptive gastritis was carried out at gastroenterology clinic of Rivers State University Teaching Hospital Port Harcourt. Two hundred and forty two (242) male and female participants were recruited randomly for the study, their stool samples were analyzed using On Site H. pylori antigen® (USA) and fecal occult blood (ROSTEC™) Rapid Diagnostic Test Kits, while characteristics and symptoms for gastritis were assessed with pretest questionnaires. Data generated from this study were statistically analyzed using MS Excel 2007 and represented in charts and tables. Results: The prevalence rate of H. Pylori was found to be 55% in Rivers State University Teaching Hospital (RSUTH) with a higher prevalence among females than males and an increase in prevalence but decline above 49 years. Conclusion: H. pylori testing should be regarded as an important aspect in clinical practice to help in treatment and better eradication of the infection in patients; this will lead to a significant decrease in gastritis in patients of different age group whether with symptoms or asymptomatic.