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Research Article Open access CC BY 4.0

The Paradigm Shift of Instant Mobile DNA Analysis in Forensic and Genomic Applications

Basanta Kumar Panigrahi, Siba Prasad Mishra

Journal of Advances in Biology & Biotechnology · pp. 103–113 · Published 3 Dec 2025

10.9734/jabb/2025/v28i123368

Abstract

Mobile DNA analysis is a forensic tool for rapid, on-site genetic profiling by integrating the processes of DNA extraction, amplification, separation, and detection into portable, automated systems beyond the laboratory and for field use. The DNA analysis in practice is time-consuming, expensive for processing delays and laboratory backlogs. The search provides a good overview of mobile Rapid DNA analysis platforms such as ANDE, RapidHIT ID and the Oxford Nanopore MinION which are fast, suitable and insitu use for forensic engineers and humanitarian applications. These decision-making handy gadgets have application in supporting crime scenes, borders and disaster sites. For rapid DNA testing for practitioners and policy makers the device serves as an introductory, didactic tool for collating technical, operational and ethical considerations unitedly. The growing need for obtaining reliable DNA results instantly, accurately and economically in real time applications for law enforcement, border security, disaster victim identification, outbreak response, and forensic and biological analyses. Mobile DNA analysis turned out as a transformative advancement bridging the gap between conventional laboratory-based profiling and real-time field operations. Its advantages include speed, portability, and real-time data generation; however, challenges such as high costs, environmental limitations, restricted sample types, and concerns over data security and ethical governance must be addressed for its widespread adoption. Overall, this innovation marks a paradigm shift in forensic and genomic applications, promoting faster and more accessible human identification and genetic analysis.

DNA STR markers ANDE RapidHIT ID system oxford Nanopore sequencing

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