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Research Article Open access CC BY 3.0

Syzygium sp (Myrtaceae) Extracts: Inhibition of Alpha Amylase

Tuanny Cavatão de Freitas, Chrystian Araujo Pereira, Luciana Lopes Silva Pereira

European Journal of Medicinal Plants · pp. 116–125 · Published 13 Nov 2013

10.9734/EJMP/2014/6781

Abstract

Aims: The aims of this study were: a) prepare crude extracts of commercial teas Syzygium sp by different methods (maceration, decoction and infusion) in different proportions (1:20, 1:50 and 1:100) and b) submit them the inhibition assays digestive enzyme alpha-amylase before and after exposure to a simulated gastric fluid. Place and Duration of Study: Laboratório de Bioquímica, Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triângulo Mineiro, Brazil, between August 2012 and July 2013. Methodology: Five samples of Syzygium sp teas were purchased commercially from pharmacies, drugstores and health food stores. Results: In the first step - inhibition of enzymatic extracts of the teas without simulated gastric fluid - the results showed significant inhibition of alpha-amylase (mean 92.84%, CV = 3.86%). However, when these extracts were placed in contact with the simulated gastric fluid was observed decreased inhibition of alpha – amylase, suggesting a possible reduction of hypoglycemic potential of these teas under physiological conditions. Conclusion: Aqueous extract Syzygium sp have high percentages of inhibition of the enzyme amylase, suggesting a potential hypoglycemic effect. Additional studies aiming at elucidating the chemical compounds present in the extracts of Syzygium sp using chromatographic techniques will be performed.  

Syzygium diabetes amylase gastric fluid

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Cited by 7

Identification of Bioactive Compounds and Analysis of Inhibitory Potential of the Digestive Enzymes fromSyzygiumsp. Extracts

Tuanny Cavatão de Freitas, Ronaldo Junio de Oliveira, Ricardo José de Mendonça · Journal of Chemistry · 2019

Hypoglycemic and Antihyperlipidemic effects of Syzygium cumini (Lamarck) Skeels and Syzygium paniculatum (Gaertn.)

Renata Junqueira Pereira, Maria das Graças Cardoso, Milene Aparecida Andrade · Revista Colombiana de Ciencias Químico-Farmacéuticas · 2022

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