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Syphilis and Human Immunodeficiency Virus Co-infection among Pregnant Women in Nigeria: Prevalence and Trend

C. T. Omisakin, A. J. Esan, K. A. Fasakin, M. F. Owoseni, O. Ojo-Bola, O. O. Aina, D. P. Omoniyi

International STD Research & Reviews · pp. 94–100 · Published 13 Jun 2014

10.9734/ISRR/2014/10946

Abstract

Pregnant women are at increased risk of sexually transmitted infections (STIs) due to physiological changes that accompany pregnancy, such as congestion of the cervix, edema of the vaginal mucosa, and alterations in the vaginal flora. Syphilis and HIV are both transmitted sexually and so it is not surprise that a substantial number of people are infected with both agents. The rate of HIV and syphilis co-infection varies depending on the prevalence of both infections in the community or the patient group being studied, along with individual risk factors. 1913 apparently healthy pregnant women were recruited for the study after obtained their consent. Detection of HIV p24 antigen and antibodies to HIV1/2 was screened for using BIO-RAD in-vitro diagnostic enzyme immunoassay; syphilis was screen for using DIA-PRO in-vitro diagnostic Bio-probes enzyme immunoassay for the determination of antibodies to Treponema pallidum. Age group 26-30 had highest prevalence of HIV and VDRL in the study years, a decreasing trend was observed in the prevalence of HIV and syphilis infection within the study years. Sero-prevalence of HIV and VDRL were 63(3.29%) and 03(0.16%) respectively. The prevalence of HIV and VDRL co-infection was 01(0.05%) observed in age group 26-30. This present study clearly documents a relatively declined in sero-prevalence of HIV and VDRL within the consecutive three years of study, this reflects the level of HIV and VDRL in the general population.

Syphilis human immunodeficiency virus mode of transmission

References (18)

  1. 1 Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 [DOI]
  2. 2 Principles and Practice of Infectious Diseases. [DOI]
  3. 3 Viral hepatitis B [DOI]
  4. 4 Increased risk of HIV-1 transmission in pregnancy [DOI]
  5. 5 Reexamining Syphilis: An Update on Epidemiology, Clinical Manifestations, and Management [DOI]
  6. 6 Economic and programmatic aspects of congenital syphilis prevention.
  7. 7 Syphilis and HIV co-infection [DOI]
  8. 8 Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana [DOI]
  9. 9 Meta-analysis: prevalence of HIV infection and syphilis among MSM in China [DOI]
  10. 10 UNGASS COUNTRY PROGRESS REPORT
  11. 11 The outer membrane, not a coat of host proteins, limits antigenicity of virulent Treponema pallidum [DOI]
  12. 12 Abnormal Vaginal Flora as a Biological Risk Factor for Acquisition of HIV Infection and Sexually Transmitted Diseases [DOI]
  13. 13 How safe are our safe donors?
  14. 14 Prevalence of HIV and VDRL seropositivity in blood donors of Delhi.
  15. 15 HIV, HBV, HCV, and syphilis co-infections among patients attending the STD clinics of district hospitals in Northern India [DOI]
  16. 16 HBsAg, anti-HCV, anti-HIV and VDRL in blood donors: Prevalence and trends in the last three and a half years in a tertiary health care facility in Ile-Ife, Nigeria [DOI]
  17. 17 Syphilis in drug users in low and middle income countries [DOI]
  18. 18 HIV infection and genital ulcer disease.

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