Synthesis and Characterization of Metal Complexes of Mg(II) and Cu(II) Ions with N-(4-hydroxyphenyl) Acetamide
Aida Smajlagić, Majda Srabovic, Melita Huremović, Zahida Ademović, Ekrem Pehlic
Journal of Scientific Research and Reports · pp. 322–330 · Published 20 Jan 2025
10.9734/jsrr/2025/v31i12773Abstract
N-(4-hydroxyphenyl) acetamide or paracetamol is an acylated aromatic amide used as analgesic and antipyretic to relieve pain and reduce body temperature. In medicinal chemistry, there is a growing interest in the development of drugs based on metal complexes, which are of great importance in therapeutic and diagnostic possibilities. Selected metals, magnesium and copper are elements that are extremely important for the human body. In this research, complexes of Mg(II) and Cu(II)-ions with N-(4-hydroxyphenyl) acetamide were synthesized and confirmed with FTIR, UV and MS spectroscopy. The results of the analysis of the synthesized complexes spectra indicate interactions between N-(4-hydroxyphenyl) acetamide and metal Mg(II)-ions and Cu (II)-ions via O-donor and N-donor atoms.
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