Synergistic Effect of Monofloral Honeys and Essential Oils against Pseudomonas aeruginosa
Laïd Boukraâ, Hasan A Alzahrani, Fatiha Abdellah, Balkees Bakhotmah, Si Mohamed Hammoudi
Microbiology Research Journal International · pp. 564–573 · Published 14 Aug 2013
10.9734/BMRJ/2013/5331Abstract
Aims: The emergence of pathogenic bacterial strains with resistance to commonly used antibiotics has necessitated a search for novel types of antibacterial agents. The main objective of this study was to evaluate the synergistic action between honeys and the essential oils (EOs) against Pseudomonas aeruginosa (ATCC 27853). Study Design and Methodology: In the first step, the minimum inhibitory concentration (MIC) of each honeys and Eos were determined. In the second step, lower concentrations of honey than the MIC were mixed with a set of sub-MIC of EOs and then added to media to determine the minimum synergistic inhibitory concentration (MSIC). Place of Study: Laboratory Research onof Local Animal Products, Ibn-Khaldoun University, Tiaret, Algeria. Results: The results indicated that the essential oils and all varieties of honey were effective against P. aeruginosa. The effectiveness was correlated to the botanical origin of honey and EOs. Wild carrot honey and Origanum vulgaris EOs were the most effective against the tested bacteria with a MIC of 8% and 2% respectively. Adding EOs to honey decreases the MIC values and the isobolographic representation shows a synergistic action between the EOs and all varieties of honey. Conclusion: The current prevalence of antibacterial resistant species has led to a re-evaluation of the therapeutic use of ancient remedies, including honey and EOs, which may receive renewed recognition as wound and burn healers.
References (24)
- 1 Antimicrobial agents from plants: antibacterial activity of plant volatile oils [DOI]
- 2 In vitro antibacterial activity of some plant essential oils [DOI]
- 3 Indian Herbs and Herbal Drugs Used for the Treatment of Diabetes [DOI]
- 4 Drug Synergism: Its Detection and Applications [DOI]
- 5 Novel antiviral agents: a medicinal plant perspective [DOI]
- 6 Antimicrobial Activity of Essential Oils from Plants against Selected Pathogenic and Saprophytic Microorganisms [DOI]
- 7 Antimicrobial and antioxidant properties of some commercial essential oils [DOI]
- 8 Value-added products from beekeeping
- 9 Antibacterial Activity of Honey against Strains of Staphylococcus Aureus from Infected Wounds [DOI]
- 10 The time-related changes of antimicrobial resistance patterns and predominant bacterial profiles of burn wounds and body flora of burned patients [DOI]
- 11 Antiviral activity of medicinal plants of Nilgiris.
- 12 Frequency of Pseudomonas aeruginosa serotypes in burn wound infections and their resistance to antibiotics [DOI]
- 13 Identification and quantitative levels of antibacterial components of some New Zealand honeys [DOI]
- 14 Antibiotic and chemotherapy : anti-infective agents and their use in therapy
- 15 Extracts and fractions of Thymus capitatus exhibit antimicrobial activities [DOI]
- 16 Antibacterial Honey (Medihoney™): in-vitro Activity Against Clinical Isolates of MRSA, VRE, and Other Multiresistant Gram-negative Organisms Including Pseudomonas aeruginosa.
- 17 Traditional uses of Salvia libanotica (East Mediterranean sage) and the effects of its essential oils [DOI]
- 18 IN VITRO ANTIBACTERIAL ACTIVITY OF CLOVE AGAINST GRAM NEGATIVE BACTERIA
- 19 Antibacterial activity of Thymus vulgaris essential oil alone and in combination with other essential oils [DOI]
- 20 Honey as an antimicrobial agent against Pseudomonas aeruginosa isolated from infected wounds [DOI]
- 21 ANTIMICROBIAL AND ANTIRADICALS ACTIVITY OF ORIGANUM VULGARE L. AND THYMUS VULGARIS ESSENTIAL OILS
- 22 The antimicrobial activity of essential oils and extracts of some medicinal plants grown in Ash-shoubak region - South of Jordan.
- 23 Inhibition of biofilms through the use of manuka honey
- 24 MAN AND WOUND IN THE ANCIENT WORLD [DOI]
Cited by 16
Fatiha Abdellah, Badra Boubakeur, Noura Ayad, Laïd Boukraâ, Si Mohamed Hammoudi, Boumedienne Abdelhak, Rachida Benaraba · Asian Journal of Applied Chemistry Research · 2021
F. Nazzaro, M. Ombra, Francesca Coppola · Antibiotics · 2024
Mouna Mekkaoui, El Houcine Bouidida, Hanae Naceiri Mrabti · Foods · 2022
Roxana Nicoleta Lazăr, E. Alexa, Diana Obiștioiu · Applied Sciences · 2022
Mouna Mekkaoui, H. Assaggaf, A. Qasem · Foods · 2021
Saliha Oussaid, Khodir Madani, Karim Houali · Food and Bioproducts Processing · 2018
Hamada Imtara, Youssef Elamine, B. Lyoussi · Evidence-Based Complementary and Alternative Medicine · 2018
D. Ganjewala, R. Mittal, A. Gupta · 2014
F. Abdellah, L. Boukraâ, S. M. Hammoudi · 2019
Showing 9 of 16 known citations — external sources report more than can currently be individually listed.
Related research
- Antibacterial Activities of Streptomyces collinus and Streptomyces refuineus from Cocoa, Orange and Timber Plantation Soils in Akure Metropolis — shares topic coverage
- Antimicrobial Activity, Phytochemical Screening and Nutrient Analysis of Tetrapleura tetraptera and Piper guineense — shares topic coverage
- Antibacterial and Antibiofilm Properties of the Crude Ethanolic, Methanolic and Aqueous Bark and Seed Extracts of Citrullus lanatus Fruit — shares topic coverage
- Susceptibility of Some Clinically Resistant Bacterial Isolates to Thyme Essential Oil, Chitosan and Lactobacillus reuteri — shares topic coverage
- Antibacterial and Antifungal Effect of Cinnamon — shares topic coverage
Article metrics
Real usage data collected on this platform.
81
Page views
0
PDF downloads
29
Outbound clicks
16
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.