Skip to content
Research Article Open access CC BY 4.0

Study of Micro Albuminuria and HbA1c in Type 2 Diabetes Mellitus Patients in Shendi Town, Sudan: Case Control Based Study

Safa Ahmed Ali, Mutaz lbrahim Hassan, Tibyan Abd Almajed Altaher, Ghanem Mohammed Mahjaf, Babbiker Mohammed Taher Gorish, Abdalwahab Abdeen Saeed, RahmaAbdo Ahmed Osman, Waha Ismail Yahia Abdelmula

Asian Journal of Research in Biochemistry · pp. 30–35 · Published 30 Dec 2022

10.9734/ajrb/2022/v11i3-4220

Abstract

Background: Diabetes mellitus (DM) is a systemic metabolic disorder that can lead to diabetic nephropathy (DN), a leading cause of end-stage renal disease around the world. Objectives: The purpose of this study was to compare microalbuminuria and glycosylated hemoglobin (HbA1c) levels in patients with diabetes mellitus to healthy normal controls in Shendi, Sudan. Materials and Methods: This hospital-based case-control study was carried out in Shendi, Sudan. Between June and October of 2021 This study included 50 participants, 30 of whom had clinically confirmed diabetes as cases and 20 who appeared to be healthy as controls. In this study, blood and random urine samples were collected from each case and control, and the levels of microalbuminuria and hemoglobin A1C (HbA1C) were estimated using an A25 chemistry analyzer and an Ichroma immuno-analyzer, respectively. The data was collected with a structured questionnaire and analyzed with SPSS version 20. Results: In our study, patients had higher mean microalbuminuria than controls (26.438.2 vs 11.4 9.2 mg/l, P value = 0.000). This study found a significant increase in mean hemoglobin A1C levels in the case group compared to the control group (7.382.2 vs5.7 0.76% P value = 0.001). Our findings also revealed that there was no relationship between microalbuminuria and disease duration. Conclusions: Microalbuminuria levels were higher when compared to controls. In comparison to the control group, HbA1c levels were higher. Microalbuminuria and patient age had a weak positive correlation in our study group.

Diabetes mellitus type 2 microalbuminuria HbA1C

References (22)

  1. 1 Projections of Global Mortality and Burden of Disease from 2002 to 2030 [DOI]
  2. 2 Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition [DOI]
  3. 3 IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045 [DOI]
  4. 4 National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants [DOI]
  5. 5 MICROALBUMINURIA AS A PREDICTOR OF CLINICAL NEPHROPATHY IN INSULIN-DEPENDENT DIABETES MELLITUS [DOI]
  6. 6 The burden and risks of emerging complications of diabetes mellitus [DOI]
  7. 7 What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium? [DOI]
  8. 8 Rising prevalence of NIDDM in an urban population in India [DOI]
  9. 9 Higher Prevalence of Elevated Albumin Excretion in Youth With Type 2 Than Type 1 Diabetes [DOI]
  10. 10 A Comparison of HbA1c and Fasting Blood Sugar Tests in General Population.
  11. 11 The prevalence of microalbuminuria in diabetes: a study from North India [DOI]
  12. 12 Exercise in the Management of Type 1 Diabetes Mellitus [DOI]
  13. 13 Prevalence of Microalbuminuria in Type 2 Diabetes Mellitus [DOI]
  14. 14 Microalbuminuria: A Major Risk Factor in Non‐insulin‐dependent Diabetes. A 10‐year Follow‐up Study of 503 Patients [DOI]
  15. 15 Study of magnesium, glycosylated hemoglobin and lipid profile in diabetic retinopathy [DOI]
  16. 16 Microalbuminuria in diabetes mellitus.
  17. 17 The Concomitants of Raised Blood Sugar: Studies in Newly-Detected Hyperglycaemics [DOI]
  18. 18 Modification of the Relationship Between Blood Pressure and Renal Albumin Permeability by Impaired Excretory Function and Diabetes [DOI]
  19. 19 Exercise-induced albuminuria and circadian blood pressure abnormalities in type 2 diabetes [DOI]
  20. 20 Comparison of glycosylated hemoglobin levels in severe periodontitis patients and healthy controls: a study in an Indian population. [DOI]
  21. 21 Acute reduction of arterial blood pressure reduces urinary albumin excretion in Type 1 (insulin-dependent) diabetic patients with incipient nephropathy [DOI]
  22. 22 GLYCOSYLATED HAEMOGLOBIN LEVELS IN PATIENTS WITH DIABETES MELLITUS [DOI]

Cited by 1

The Magnitude and Related Risk Factors of Obesity and Overweight among Medical Students at Shendi University, Sudan

Abdallah Abu Shammala, Layla A. Ali, Omnia M. Hassan · SAR Journal of Pathology and Microbiology · 2024

Related research

Article metrics

Real usage data collected on this platform.

64

Page views

0

PDF downloads

20

Outbound clicks

1

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.