Neurological-Onset Vogt–Koyanagi–Harada Disease with Delayed Ocular Involvement: An Atypical Case with Favorable Outcome
ASMAE NAJAH, Niama El Fahli, HIND SAFI, SOUMIA ALLAOUI, YOUNES TLEMCANI, SARAH BELGHMAIDI, ABDELJALIL MOUTAOUAKIL
Ophthalmology Research: An International Journal · pp. 27–32 · Published 23 May 2026
10.9734/or/2026/v21i3514Abstract
Vogt–Koyanagi–Harada Disease is an uncommon systemic autoimmune disorder that predominantly affects young adults. Its diagnosis relies on a combination of clinical and paraclinical findings, but may be delayed because of atypical presentations. We report the case of a 26-year-old woman initially managed for idiopathic intracranial hypertension, in whom the subsequent development of bilateral granulomatous panuveitis associated with exudative retinal detachment led to the diagnosis of incomplete VKH disease. Early initiation of high-dose corticosteroid therapy combined with immunosuppressive treatment resulted in complete visual recovery. This case highlights the importance of early diagnosis in improving visual prognosis and preventing progressive complications.
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