Separation of Palmitic and Palmitoleic Acid Using Transition Metal Salts: Experimental vs Theoritical Analyses
Sayali Kulkarni, Sandun Fernando
International Research Journal of Pure and Applied Chemistry · pp. 1–11 · Published 8 Sep 2014
10.9734/IRJPAC/2015/11921Abstract
Fatty acids (FAs) play a major role in many physiological functions and offer various health benefits. Separation and isolation of fatty acids thus, is of great interest. A set of experiments were conducted to evaluate the effectiveness of select transition metal salts in separating a saturated FA from mixture of C16:0 and C16:1 FAs. In an initial study, ZnSO4, CuSO4 and AgCl were able to cause significant precipitation of C16:0 FA from a mixture of C16:0 and C16:1 FAs in methanol. A follow-up study was conducted to ascertain the effect of ZnSO4 concentration on the ability to separate individual FAs from a mixture of saturated and unsaturated FAs in methanol. Results indicated that a 30 mg/ml ZnSO4 solution could remove 58% of C16:0 FA from a mixture containing both the saturated and the unsaturated FA forms. IR spectra suggest formation of a complex between zinc ion and the carboxylate group of the C16:0 FA, which in turn may cause precipitation. Computational chemistry calculations indicate that specific complex formation with the saturated FA might be due to more favorable thermodynamics between zinc ion - C16:0 FA complexation (with more negative value of Gibbs free energy of the reaction) than that between the metal ion and the unsaturated FA.
References (29)
- 1 Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials [DOI]
- 2 Examination of Ionic Liquids and Their Interaction with Molecules, When Used as Stationary Phases in Gas Chromatography [DOI]
- 3 Correlation of infrared spectra of zinc(II) carboxylates with their structures [DOI]
- 4 Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents [DOI]
- 5 Essentiality of fatty acids [DOI]
- 6 Omega-3 fatty acid concentrates: nutritional aspects and production technologies [DOI]
- 7 Recent developments in comprehensive two-dimensional gas chromatography (GC×GC) [DOI]
- 8 Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes [DOI]
- 9 A rapid GC–MS method for quantification of positional and geometric isomers of fatty acid methyl esters [DOI]
- 10 Concentration of omega 3-polyunsaturated fatty acids of seal blubber oil by urea complexation: optimization of reaction conditions [DOI]
- 11 Recent developments in comprehensive two-dimensional gas chromatography (GC×GC) [DOI]
- 12 Retention of lipids in silver ion high-performance liquid chromatography: Facts and assumptions [DOI]
- 13 Separations of lipids by silver ion chromatography [DOI]
- 14 Omega-3 ( n -3) Fatty Acids in Health and Disease: Part 1—Cardiovascular Disease and Cancer [DOI]
- 15 Organic Corrosion Inhibitors in Neutral Solutions; Part 1 — Inhibition of Steel, Copper, and Aluminum by Straight Chain Carboxylates [DOI]
- 16 Inhibition of lead corrosion with saturated linear aliphatic chain monocarboxylates of sodium [DOI]
- 17 Overview of methods for the determination of trans fatty acids by gas chromatography, silver-ion thin-layer chromatography, silver-ion liquid chromatography, and gas chromatography/mass spectrometry.
- 18 DHA Concentration and Purification from the Marine Heterotrophic Microalga Crypthecodinium cohnii CCMP 316 by Winterization and Urea Complexation
- 19 Urea complexation for the rapid, ecologically responsible fractionation of fatty acids from seed oil [DOI]
- 20 Stationary phases for silver ion chromatography of lipids: Preparation and properties [DOI]
- 21 Effect of fractional winterization of beef tallow biodiesel on the cold flow properties and viscosity [DOI]
- 22 Corrosion Inhibition of Rapidly Solidified Mg-3% Zn-15% Al Magnesium Alloy with Sodium Carboxylates [DOI]
- 23 Determination of Polyunsaturated Fatty Esters (PUFA) in Biodiesel by GC/GC–MS and 1H‐NMR Techniques [DOI]
- 24 Optimisation of urea complexation by box-behnken design
- 25 HPLC of fatty acid esters of mono‐ and polyhydric alcohols. Part 1: Analytical separation [DOI]
- 26 Separation of Ethyl Esters of Eicosapentaenoic Acid and Docosahexaenoic Acid by Circulating Liquid Membranes Using Silver Nitrate as a Carrier. Uphill Transport by Use of Temperature and Solvent Dependencies of Distribution Ratio [DOI]
- 27 Extraction of Polyunsaturated Fatty Acid Ethyl Esters from Aqueous Silver Nitrate Solution using Supercritical Ethane and Ethylene and Modeling of the Extraction Process. [DOI]
- 28 A laboratory manual of chemistry
- 29 Separation of Palmitic and Palmitoleic Acid and their FAMEs using Transition Metal Salts [DOI]
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