Skip to content
Research Article Open access CC BY 4.0

Seasonal Depiction of Malariometric Indices in Children under Five Years in a Sudanese Semi-urban Area of Burkina Faso

San M. Ouattara, Alphonse Ouédraogo, Alfred B. Tiono, Benjamin Sombié, Amidou Diarra, Issa N. Ouédraogo, Michel Vaillant, Sodiomon B. Sirima

International Journal of TROPICAL DISEASE & Health · pp. 1–12 · Published 13 Jul 2019

10.9734/ijtdh/2019/v37i230159

Abstract

Aims: Malariometric indices are essential for the assessment of both new therapies and control strategies. As part of the characterization of a new malaria clinical trial site, this study was carried out to assess malariometric indices during the two seasons of a Sudanese area of Burkina Faso, in children aged under five years. Study Design: Two community-based cross-sectional surveys were conducted as follow: the first during the rainy season of 2009 and the second during the following dry season. Socio-demographic and clinical data were recorded. A finger prick blood sample was collected to perform malaria blood films and to measure the hemoglobin level. Results: Malaria parasitemia prevalence was 55.2% (N = 677) in the rainy season with a geometric mean of parasite density (GMPD) of 3439 trophozoites/µl against 23.3% (N = 720) in the dry season with a GMPD of 1368 trophozoites/µl. Gametocytemia prevalence was 21.7% and 6.5% respectively in rainy and dry season while splenomegaly prevalence was 11.2% (N = 689) in rainy season against 4.2% (N = 752) in dry season. The prevalence of anemia (hemoglobin < 11.0 g/dl) was 90.0% in rainy season and 70.6% in dry season. All indices in rainy season were statistically higher than those in dry season (p-value < 0.0001). The odds of parasite carriage were 3 to 5 times higher in rainy season compared to dry season (95% CI for OR = [3.1, 5.0]). Conclusion: The site is located in a seasonal hyper-endemic malaria area and seems appropriate for the conduct of malaria drugs or vaccines studies. Though the gap between seasons is considerable, the residual level of parasite carriage during low transmission period is not negligible and may command the development of strategies targeting this specific period, to break the chain of transmission of the disease.

Malariometric indices season children Burkina Faso

References (6)

  1. 1 Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study [DOI]
  2. 2 Measuring malaria endemicity from intense to interrupted transmission [DOI]
  3. 3 Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya. [DOI]
  4. 4 Malaria Morbidity in High and Seasonal Malaria Transmission Area of Burkina Faso [DOI]
  5. 5 Seasonal patterns of Plasmodium falciparum gametocyte prevalence and density in a rural population of Burkina Faso [DOI]
  6. 6 Malaria case clinical profiles and Plasmodium falciparum parasite genetic diversity: a cross sectional survey at two sites of different malaria transmission intensities in Rwanda [DOI]

Cited by 1

1 citation reported by external sources — individual citing-article records aren't available to list yet.

Related research

Article metrics

Real usage data collected on this platform.

0

Page views

0

PDF downloads

0

Outbound clicks

1

Citations

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

No views recorded yet.

Traffic sources

Referring site, by host.

No traffic recorded yet.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.