Screening and Characterization of Antimalarial Heme Polymerase Inhibitors from Garlic Cloves

References (48)

1. 1 The economic and social burden of malaria [DOI]
2. 2 Health benefits of herbs and spices: the past, the present, the future [DOI]
3. 3 HEMOGLOBIN METABOLISM IN THE MALARIA PARASITEPLASMODIUM FALCIPARUM [DOI]
4. 4 Clarifying the Real Bioactive Constituents of Garlic [DOI]
5. 5 Therapeutic actions of garlic constituents [DOI]
6. 6 Historical Perspective on the Use of Garlic [DOI]
7. 7 On the molecular mechanism of chloroquine's antimalarial action. [DOI]
8. 8 Insect repellents: Historical perspectives and new developments [DOI]
9. 9 An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials [DOI]
10. 10 Therapeutic Potential of Quercetin to Decrease Blood Pressure: Review of Efficacy and Mechanisms [DOI]
11. 11 Cancer chemoprevention with garlic and its constituents [DOI]
12. 12 Antimalarial drugs inhibiting hemozoin (β-hematin) formation: A mechanistic update [DOI]
13. 13 Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: A randomised controlled trial [DOI]
14. 14 The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability [DOI]
15. 15 Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.
16. 16 The Role of Diallyl Sulfides and Dipropyl Sulfides in the In Vitro Antimicrobial Activity of the Essential Oil of Garlic, Allium sativum L., and Leek, Allium porrum L. [DOI]
17. 17 Falcipains and Other Cysteine Proteases of Malaria Parasites [DOI]
18. 18 Insecticidal, antimicrobial and antioxidant activities of bulb extracts of Allium sativum [DOI]
19. 19 Allicin Induces p53-Mediated Autophagy in Hep G2 Human Liver Cancer Cells [DOI]
20. 20 Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1 [DOI]
21. 21 Simple Colorimetric Inhibition Assay of Heme Crystallization for High-Throughput Screening of Antimalarial Compounds [DOI]
22. 22 Antiplasmodial activity of flavonol quercetin and its analogues in Plasmodium falciparum: evidence from clinical isolates in Bangladesh and standardized parasite clones [DOI]
23. 23 Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial Parasite [DOI]
24. 24 Hemoglobin catabolism and iron utilization by malaria parasites [DOI]
25. 25 Antimalarial Activity of Allicin, a Biologically Active Compound from Garlic Cloves [DOI]
26. 26 New evidences of antimalarial activity of Bidens pilosa roots extract correlated with polyacetylene and flavonoids [DOI]
27. 27 Heme Aggregation Inhibitors: Antimalarial Drugs Targeting an Essential Biomineralization Process [DOI]
28. 28 Solid-phase microextraction–gas chromatographic–mass spectrometric analysis of garlic oil obtained by hydrodistillation [DOI]
29. 29 Heme-Artemisinin Adducts Are Crucial Mediators of the Ability of Artemisinin to Inhibit Heme Polymerization [DOI]
30. 30 Allicin enhances host pro-inflammatory immune responses and protects against acute murine malaria infection [DOI]
31. 31 Allicin and derivates are cysteine protease inhibitors with antiparasitic activity [DOI]
32. 32 Ayurveda and Yoga in Cardiovascular Diseases [DOI]
33. 33 Clotrimazole Inhibits Hemoperoxidase of Plasmodium falciparum and Induces Oxidative Stress [DOI]
34. 34 Role of the NF-κB transcription pathway in the haemozoin- and 15-HETE-mediated activation of matrix metalloproteinase-9 in human adherent monocytes [DOI]
35. 35 Synthesis and in vitro evaluation of new chloroquine-chalcone hybrids against chloroquine-resistant strain of Plasmodium falciparum [DOI]
36. 36 A review of antimalarial plants used in traditional medicine in communities in Portuguese-Speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola [DOI]
37. 37 Haemozoin Induces Early Cytokine-Mediated Lysozyme Release from Human Monocytes through p38 MAPK- and NF-kappaB- Dependent Mechanisms [DOI]
38. 38 Hypolipidemic effect of garlic protein substituted for casein in diet of rats compared to those of garlic oil.
39. 39 Heme Metabolism of Plasmodium Is a Major Antimalarial Target [DOI]
40. 40 In vitro and in vivo assessment of the anti-malarial activity of Caesalpinia pluviosa [DOI]
41. 41 Quercetin protects against testicular toxicity induced by chronic administration of therapeutic dose of quinine sulfate in rats [DOI]
42. 42 Identification and screening of antimalarial phytochemical reservoir from northeastern Indian plants to develop PfRIO-2 kinase inhibitor [DOI]
43. 43 New mannose-specific lectins from garlic (Allium sativum) and ramsons (Allium ursinum) bulbs [DOI]
44. 44 Effects of allyl mercaptan and various allium-derived compounds on cholesterol synthesis and secretion in Hep-G2 cells [DOI]
45. 45 Antimalarial natural products drug discovery in Panama [DOI]
46. 46 Bioflavonoid effects on in vitro cultures of Plasmodium falciparum [DOI]
47. 47 Adenomatoid tumors of the uterus.
48. 48 [Malaricide activity of the quercetin in Gallus gallus L., 1758 immunocompromised infected by Plasmodium (Bennettinia) juxtanucleare Versiani and Gomes, 1941].

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