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Research Article Open access CC BY 4.0

SARS-CoV-2 Infection and Factors Associated with Mortality in Hospitalized Patients Aged 60 and Over at the Epidemic Treatment Center (ETC) of Saint-Louis (Senegal)

Alassane Dièye, Arona Diouf, Papa Latyr Junior Diouf, Moustapha Diedhiou, Mba Bambo Diakhaby, Demba Makalou, Samba Niang, Diatou Dia-Gueye, Amadou Diop Dia, Ibrahima Louis Martin Dieng, Ahmeth Dieng, Seynabou LO, Ndéye Méry Dia-Badiane

Asian Journal of Research in Infectious Diseases · pp. 13–23 · Published 23 Feb 2024

10.9734/ajrid/2024/v15i2327

Abstract

Background: SARS-CoV-2 infection typically causes severe pneumonia in elderly patients with high mortality rates. Aim: This study aimed to describe the epidemiological, clinical, paraclinical and evolution profile of the SARS-CoV-2 infection in patients aged 60 years and over hospitalized at the Epidemic Treatment Center (ETC) of Saint-Louis “Senegal”, and to identify the factors associated with death. Methodology: This is a cross-sectional, retrospective, descriptive and analytical study conducted from March 2020 to August 2021. It includes all patients aged 60 years and older hospitalized at the ETC of Saint-Louis (Senegal) for SARS-CoV-2 infection.  Microsoft Excel was used to enter data and then analysis was done using EPI INFO version 7 software. Results: Of a total of 448 hospitalizations, 188 patient records aged 60 years and older was collected. The prevalence was 42%. The mean age was 70 years (±8 years). The sex ratio was 1.7 with a male predominance (62.8%). Hypertension was the most common co-morbidity (67%). Severe forms were predominant (64.4%). Dyspnea (60.3%), cough (56.5%) and ageusia (24.5%) were the most common symptoms on admission. Thoracic CT scans showed severe involvement in 51.7% of cases. Hydroxychloroquine-azithromycin combination was prescribed in 98.4% of cases. The mortality rate was 18.6%. The main factors associated with death were age (≤75 years) (p=0.014) [OR=0.488; 95% CI: 0.201-1.187]; critical forms (p=0.017) [OR=0.061; 95% CI: 0.006-0.601]; comorbidity (p=0. 031) [OR=1.647; 95% CI: 0.280-2.499]; occurrence of complications (p=0.009) [OR=1.212; 95% CI: 0.530-2.774]; and SpO2≤95% at admission (p=0.031) [OR=4.899; 95% CI: 0.752-8.797]. Conclusion: SARS-CoV-2 infection in the elderly is predominantly severe with high mortality. This high-risk group requires special attention.

SARS-CoV-2 elderly patients Saint-Louis Senegal

References (17)

  1. 1 World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19) [DOI]
  2. 2 Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up [DOI]
  3. 3 Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study [DOI]
  4. 4 Clinical characteristics of older patients infected with COVID-19: A descriptive study [DOI]
  5. 5 Association of frailty with mortality in older inpatients with Covid-19: a cohort study [DOI]
  6. 6 The first year of COVID-19 vaccine roll-out in Africa: challenges and lessons learned [DOI]
  7. 7 Clinical course and mortality in older patients with COVID-19: a cluster-based study in Hong Kong [DOI]
  8. 8 Gestion de la pandémie COVID-19 au Sénégal [DOI]
  9. 9 Clinical characteristics of older patients with COVID-19: a systematic review of case reports [DOI]
  10. 10 COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis [DOI]
  11. 11 Manifestations cliniques et paracliniques de la COVID-19, diagnostic virologique [DOI]
  12. 12 Persistance et protection des anticorps neutralisants 12 mois après l’infection à SARS-COV-2 chez les sujets âgés [DOI]
  13. 13 Epidémiologie et stratégies de riposte contre la covid-19 : l’expérience sénégalaise de 2020 à 2021 [DOI]
  14. 14 L’infection à SARS-CoV-2 [DOI]
  15. 15 Infection liée à la COVID-19 chez une série de sujets âgés : résultats d’une étude préliminaire [DOI]
  16. 16 Réponse immunitaire associée au Sars-CoV-2 [DOI]
  17. 17 Manifestations Cliniques de la COVID-19 [DOI]

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