Role of Antioxidant in Testicular Integrity
B. J. Dare, F. Oyeniyi, O. T. Olaniyan
Annual Research & Review in Biology · pp. 998–1023 · Published 17 Dec 2013
10.9734/ARRB/2014/4453Abstract
Spermatogenesis is an extremely active replicative process capable of generating approximately 1000 sperms a second with correspondingly high rates of mitochondrial oxygen consumption by the germinal epithelium. This process generates reactive oxygen species (ROS) through reactions with drugs and environmental toxins, or when the level of antioxidants is diminished results in oxidative stress. Excessive production of free radicals or ROS can damage sperm, testes and can cause serious chemical damage to biomolecules (DNA, proteins, and unsaturated lipids) which ultimately lead to cell death and cause infertility. The cell has several protective mechanisms that minimize the toxic potential of these reactive oxygen species. These include the low oxygen tension in the tissue and also the elaborate array of antioxidant enzymes and free radical scavengers it contains; to ensure that the spermatogenic and steroidogenic functions of this organ are not impacted by oxidative stress.
Cited by 18
E. Olayinka, A. Ore, O. A. Adeyemo · Porto Biomedical Journal · 2018
Ngoumtsop Victor Herman, N. Ferdinand, Ngouateu Omer Bébé · 2017
Saumya Sm, P. Mahaboob Basha · Biological Trace Element Research · 2016
K. Şahi̇n, C. Orhan, F. Akdemir · BMC Complementary and Alternative Medicine · 2016
O. Omran, O. H. Omer · Pathology, Research and Practice · 2015
O. Ogundoyin, Anne Fiyinfoluwa Sanwo · Anatomy journal of Africa · 2019
P. Dzeufiet, Marguerite Francine Mballa, D. C. Bilanda · 2019
Fatima Alaryani, Fatima Jaber, Boudor Almutiri · Journal of Advanced Veterinary and Animal Research · 2024
Related research
- In vitro Antioxidant and Anticancer Activity of Cyanobacteria — shares topic coverage
- Review: Parkia speciosa as Valuable, Miracle of Nature — shares topic coverage
- A Selective Review of Lipid Autoxidation and Rancidity, Antioxidants, and Dithiooxamide — shares topic coverage
- Antioxidant and Haemato-Biochemical Enhancing Properties of Daucus carota in Male Wistar Rats Toxicated with Lead Chloride — shares topic coverage
- Radical Scavenging Capacity and Efficacy of Myristica fragrans (Nutmeg) Metabolites on Cladosporum herbarum of Food Origin — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
18
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.