Circulating Serotypes of Group A Rotavirus Identified in the Faeces of Children Aged 0-56 Months with Gastroenteritis
I. Tondé, D. Kambiré, A. Ky-Ba, D. C. Drabo, M. T. Gampiné, J. Tranchot-Diallo, H. Savadogo, M. Tamboura, M. Kam, M. Sanou, A. S. Ouédraogo, I. Sanou, L. Sangaré, R. Ouédraogo-Traoré
Asian Journal of Research in Infectious Diseases · pp. 1–8 · Published 7 Jan 2024
10.9734/ajrid/2024/v15i1320Abstract
Gastroenteritis is a public health problem in developing countries such as Burkina Faso. The introduction of the RotaShield rotavirus vaccine in the early 1980s had the side-effect of causing acute intestinal invaginations, which led to the introduction of surveillance. The aim of this study is to review the serotypes of rotavirus identified. This retrospective study consisted in collecting data on group A rotavirus serotypes identified from stool samples using a rapid diagnostic test, confirmed by an ELISA test and then serotyped by real-time multiplex RT-PCR. A total of 840 suspect stools were collected between December 2013 and December 2017. Confirmed cases represented an average of 37.7%. Genotyping identified the P6(59.6%) and P8(40.4%) types of the P genotype in the VP4 genotype and G12 which predominates with 66% in the VP7 genotype followed by G3 23.4%. The genotypes most involved in gastroenteritis are serotypes P6 and P8 of the P genotype and serotypes G1, G2, G3, G9 and G12 of the G genotype in this study showed that.
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