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Research Article Open access CC BY 4.0

Basic Pharmacology of NG -Nitro – L – Arginine Methyl Ester

Muhanad S. Abdelwahab, Mukhallad A. M. Mohammed, H. M. Abdelwhab, Mazin S. Abdalla Mohamed, Mansour Abdelgader Bellal

Journal of Advances in Medical and Pharmaceutical Sciences · pp. 1–5 · Published 30 Jan 2019

10.9734/JAMPS/2018/46307

Abstract

NG – Nitro- L- arginine methyl ester (L-NAME) is a synthetic drug in which a quanidino is substituted for L-arginine analoques. It is a competitive enzyme inhibitor which inhibits nitric oxide synthase, hence, decreasing nitric oxide production [1].

L-NAME pharmacodynamics pharmacokinetic NG- L- arginine Nitric Oxide (NO) hypertension

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