Recurrent Dermatofibrosarcoma Protruberance over Shoulder: An Unresolved Problem
Sachin S. Kadam, Tejaswini Kadam
International Research Journal of Oncology · pp. 146–155 · Published 5 Jun 2021
Abstract
Introduction: We are reporting a case of recurrent Dermatofibrosarcoma protuberans (DFSP) over right shoulder in a 36 year young lady who underwent re-excision with secondary healing. DFSP is common in both, men and women with a slight male predominance. They are characterized by a unique translocation of chromosome i.e. t(17;22) (q22;q13). Majority of DFSPs are low grade (85-90 %) while the rest contain a high-grade sarcomatous component (DFSP-FS) and are considered to be intermediate-grade sarcomas. Trunk and proximal extremities are the most common location, usually on the chest and shoulders. Persistently recurring tumors have an increased risk for transformation into a more malignant form (DFSP-FS). Metastases to regional lymph nodes are extremely rare and distant hematogenous metastases are even rarer. Adequate lateral and deeper margin resection is necessary for excision of resectable primary DFSP and team approach is must for tackling recurrent and metastatic DFSP.
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