Physiological Reaction of Erythrocytes’ Micro Rheological Features in Newborn Piglets on Unfavourable Environmental Factors

Abstract

The aim of research is to find out peculiarities of erythrocytes’ micro rheological features in piglets having undergone the impact of the most abundant unfavourable factors of the environment. We observed 78 newborn piglets having undergone the impact of unfavourable environmental factors: 25 – prenatal iron deficiency, 28 – had undergone acute hypoxia at birth and 25 – had undergone super cooling with consequent development of dyspepsia. Control group was composed of 36 healthy newborn piglets. In our research biochemical, hematological and statistical methods of investigation were applied. There was found similar intensity increase of lipids’ peroxidation against the background of comparable weakening of their antioxidant protect ability in blood plasma and erythrocytes of newborn piglets having undergone mentioned above unfavourable environmental factors. Newborn piglets with iron deficiency, after acute hypoxia and super cooling were found to have the rise of similar evidence of reversibly changed (approximately on 45%) and irreversibly changed (nearly in 2 times) erythrocytes’ forms, rise of erythrocytes’ involvement into aggregates on more than 40% and quantity rise of their aggregates on more than 30%. Under the impact of unfavourable environmental factors newborn piglets had activation of lipids’ peroxidation in blood plasma and erythrocytes in the result of comparable weakening of their antioxidant protectability. Newborn piglets, which had undergone the impact of unfavourable environmental factors, had increased the quantity of erythrocytes’ changed forms and strengthening of their ability to aggregation, the degree of which didn’t depend on the character of preceded impact on their bodies.