Prospective Evaluation of Vitamin D Supplementation on Peripheral Neuropathy in Type 2 Diabetes Mellitus -A Review
Faisal Suliman Algaows, Fatema Abdullah Althkerallah, Norah Abdulmohsen Alsuwailem, Amnah Abdulnasser Mawlan Ahmed, Razan Fahad Alwagdani, Sarh Abdulhameed Alomran, Bayan khalid Y. Alwasifir, Ohoud Muqbil Almutairi, Hawra Abdulmohsen Alfrdan, Ziad Saloum Aldebas, Khuolod Saeed Alqahtani, Alaa Abdulrahman Alfayez, A. Alfadhli, Rahaf Fahad
Journal of Pharmaceutical Research International · pp. 260–266 · Published 30 Sep 2021
10.9734/jpri/2021/v33i45A32742Abstract
Diabetic neuropathy is a long-term consequence of diabetes that can cause significant morbidity and a decline in quality of life in many individuals. Low vitamin D levels, in addition to causing rickets in infants and chondrosteoma in adults, may have a role in the development of DM and its underlying disorders, according to a growing body of evidence. Vitamin D deficiency has been linked to type 1 or type 2 diabetes, as well as the microvascular and macrovascular problems that come with it. Vitamin D insufficiency has been linked to diabetic peripheral neuropathy (DPN) as an independent risk factor. Vitamin D, both topical and oral, has been shown to considerably improve DPN symptoms and pain.
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