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Research Article Open access CC BY 4.0

Propagation, Phytochemistry and Pharmacology of Plumbago indica - A Review

H. A. S. A Priyanjani, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Wathuge Thamara Priyanthi Sandun Kumari Senarath, M. L. A. M. S. Munasinghe

Journal of Pharmaceutical Research International · pp. 188–202 · Published 1 Sep 2021

10.9734/jpri/2021/v33i42B32439

Abstract

Aims: Plumbago indica is a medicinal plant widely grown in the tropics and temperate region to use in traditional systems of medicine. Different parts of this plant are used to treat rheumatoid arthritis, dysmenorrhea, cancer, leprosy, syphilis, rheumatism, paralysis, headache, leukoderma, enlarged glands, scabies, ophthalmia, dyspepsia, haemorrhage, piles, flatulence, loss of appetite etc. Various kinds of researches were carried out in different countries on propagation and pharmacology of this medicinal plant. Scientifically proven data were concentrated on this paper to facilitate reliable convenience data source and encourage further studies. Methodology: Scientific data published on full papers, abstracts about morphology, growth, propagation, traditional medicinal uses and pharmacology of P. indica over 70 years (1949-2020) by researchers in different countries were collected and categorized under suitable topics. Results: According to literature P. indica leaves, stems, roots contain phytochemical compound that are responsible for its medicinal properties. Tissue culture of this plant can be uses as effective propagation method to fulfill the increasing demand of raw materials (dried plant parts) for medicinal preparations as well as preserve the plant in their natural habitat. Value: P. indica is used to treat vast range of diseases in traditional medicinal systems in different countries and currently pharmacological experiments are conducting to prove it scientifically. Plumbagin present in P. indica roots was already identified as a potential anti-cancer agent and subjected to more research interest. Therefore this review article helps new researchers to get wide knowledge about the plant and its pharmacology.

Plumbaginaceae Plumbago indica plumbagin anti-cancer pharmacology

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