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Research Article Open access CC BY 4.0

Preliminary Phytochemical Analysis of Anti Hyperlipidimic and Xanthine Oxidase Inhibitory Activities of Malus domestica

A. Ruhina Hussaini, V. Vishnu Priya, R. Gayathri, S. Kavitha

Journal of Pharmaceutical Research International · pp. 758–764 · Published 30 Dec 2021

10.9734/jpri/2021/v33i64B36289

Abstract

Introduction: Malus domestica is a well known plant commonly known as apple belonging to the family Rosaceae. The fruit is rich in flavonoids and many other phytochemicals. The fruit is also reported to have many therapeutic properties. Aim: The aim of this study is to analyse phytochemical constituents and to evaluate antihyperlipidemic and xanthine oxidase inhibitory activities of Malus domestica aqueous extract. Materials and Methods: The phytochemical screening, and assessment of in vitro anti cholesterol and xanthine oxidase inhibitory activity were done in aqueous extract of Malus domestica using standard procedures. Results and Discussion: Many phytochemical elements, such as alkaloids, proteins, amino acids, terpenoids, flavonoids, carbohydrates, saponins, and steroids, were found in Malus domesticus extract. The extract also has anticholesterol effect in vitro, according to the findings. The extract is also efficient in inhibiting the xanthine oxidase inhibitory activity in a concentration dependent manner. The results obtained in the study show that Malus domestica has significant anti cholesterol and antioxidant activities. Conclusion: The present study established the potent in vitro anti cholesterol and xanthine oxidase inhibitory potential of Malus domestica.

Innovative technique cholesterol xanthine oxidase antioxidant activities Malus domestica novel method

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