Polybacteria in Urinary Tract Infection among Antenatal Patients Attending University Teaching Hospital Ado-Ekiti, Ekiti State, Nigeria

Abstract

A study of the polybacteria in UTI among antenatal patients attending clinics at the Ekiti State University Teaching Hospital, Ado-Ekiti, southwest, Nigeria was conducted between October, 2009 and July, 2011. Two hundred consenting symptomatic and asymptomatic pregnant women were recruited into the study and clean-catch midstream urine samples were collected from them. Structured questionnaires were also administered to the subjects to obtain relevant socio-demographic data from them. The results showed that 98(49%) out of the 200 samples had significant bacteria growth, 22 (11%) yielded growth of Candida albicans, 30 (15%) yielded no significant growth, 14 (7%) yielded mixed growth of contaminants, while 44 (22%) yielded no bacteria growth. Microscopically, the presence of Trichomonas vaginalis was detected in 8 (4%) of the samples. Thirty (28.8%) of the samples yielded growth of Escherichia coli, Klebsiella spp 28 (26.9%), Staphylococcus spp 22 (21.2%), Pseudomonas spp 10 (9.6%), Proteus spp 6 (5.8%) and Streptococcus spp 2 (1.9%). Statistical analysis of the result reveal that there’s an association between polybacteria UTI and subjects’ socio-economic status. It was more prevalent in subjects with low socio-economic status, was highest in subjects’ in first trimester and lowest in the third trimester. Antibiotic susceptibility testing shows that the isolates had high sensitivity to peflacine, gentamicin, nitrofurantoin, rocephin and cloxacillin. They had fairly good sensitivity to ciprofloxacin and nalidixic acid, whereas they had moderate sensitivity to chloramphenicol and zinacef. They were however resistant to tetracycline, cotrimoxazole, colisitn, streptomycin, ampicillin and penicillin.