Association between Serum Alfa Fetoprotein and Placenta Previa-Benghazi Medical Center

Abstract

Placenta Previa occurs when the placenta is wholly or partially implanted in the lower uterine segment. The exact cause of Placenta Previa is not known, but there is association with various risk factors. The study included 103 placenta Previa cases and 96 control cases. Case control design was used and duration of the study was during August 2020 to January 2021.The most common risk factors associated with study was placenta Previa were, advanced maternal age, history of previous antepartum hemorrhage, previous cesarean section and preterm deliveries and history of present antepartum hemorrhage & postpartum hemorrhage and cesarean section deliveries with preterm deliveries. There was a statistically significant difference between mean of maternal serum alfa fetoprotein of placenta Previa cases which was obviously higher as compared to control group. All cesarean hysterectomy cases had high level of SAFP. This difference was statistically significant. From the present study, it is recommended that there is a need for comprehensive obstetrics care to appropriately treat Placenta Previa and its complications. This calls for proper screening for level of maternal serum alfa fetoprotein, examination and health education during the antenatal care.