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Research Article Open access CC BY 4.0

Phytochemical Profile, Antioxidant and Antibacterial Activities of Ephedra alata Extract against Pathogenic Bacteria

Djahra Ali Boutlelis, Benkaddour Mounia, Benkherara Salah, Shaib Inass, Laib Ibtissam, Benine Chaima, and Bdida Soumaya

Journal of Complementary and Alternative Medical Research · pp. 16–23 · Published 14 Nov 2022

10.9734/jocamr/2022/v19i3392

Abstract

Plants have been a source of important chemical compounds that can be used for treatment of different disease. Natural products in plants also are a source of active compounds and can be considered an alternative to synthetic molecules with high antioxidant potential. Objective of this study was to determine the antioxidant and antibacterial potential of Ephedra alata extract. Methods: Phytochemical values namely, total phenolic, DPPH radical scavenging effect were studied by established methods. Antimicrobial properties of Ephedra alata was tested using cup-plate diffusion method and disc diffusion. Results showed numerous secondary metabolic products including in plant Ephedra alata extract such as Flavonoids, Saponins, Tannins were detected. And other metabolic products such as Steroids and Cardinolids are absent.  The yield for the aqueous extract was 9.89%. However, the polyphenols extract content was equal to 0.004243 (mg GAE/ml extract. Effectiveness of antioxidant plant using DPPH free root was estimated at IC50= 0.901 mg/ml for aqueous extract. In antibacterial screening, the extract showed antibacterial power with zone of inhibitions compared to positive controls Penicillin against multi-resistant germs such as: Pseudomonase aeruginosa and Serratia fonticola responsible of many infectious. Growth inhibition varies with bacterial species and concentration of Ephedra alta extract.

Antioxidant antibacterial activity Ephedra alata penicillin multi-resistant germs

References (26)

  1. 1 Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents [DOI]
  2. 2 Biological Activities of Polyphenols from Grapes [DOI]
  3. 3 Radical scavenging and antioxidant activity of tannic acid [DOI]
  4. 4 Anti-Candida activity of Brazilian medicinal plants [DOI]
  5. 5 Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan. (Asteraceae) [DOI]
  6. 6 Screening of antioxidant activity and antioxidant compounds of some edible plants of Thailand [DOI]
  7. 7 Phenolic composition of Cynara cardunculus L. organs, and their biological activities [DOI]
  8. 8 Evaluation of antioxidant activities of various solvent extracts of Carissa opaca fruits [DOI]
  9. 9 Antioxidant and antimicrobial activities of the edible medicinal halophyte Tamarix gallica L. and related polyphenolic constituents [DOI]
  10. 10 Identification and quantification of antioxidants in Fructus lycii [DOI]
  11. 11 Antioxidant and antilisterial activity of olive oil, cocoa and rosemary extract polyphenols [DOI]
  12. 12 Polyphenol interactions: astringency and the loss of astringency in ripening fruit☆ [DOI]
  13. 13 Screening for antimicrobial activity of some medicinal plants species of traditional Chinese medicine [DOI]
  14. 14 Antioxidant and antibacterial activity of different parts of Leucas aspera [DOI]
  15. 15 Natural Product Isolation [DOI]
  16. 16 Characterization of Phenolic Constituents from Ephedra Herb Extract [DOI]
  17. 17 Investigation of antioxidant properties of Nasturtium officinale (watercress) leaf extracts.
  18. 18 Antidiabetic Potential and Chemical Constituents of Haloxylon scoparium Aerial Part, An Endemic Plant from Southeastern Algeria [DOI]
  19. 19 Flavonoid constituents of Ephedra alata [DOI]
  20. 20 Flavonoids from Ephedra aphylla [DOI]
  21. 21 Antioxidant and hepatoprotective Potential of Coriandrum sativum L. against hepatic injury by Lambda-cyhalothrin insecticide [DOI]
  22. 22 Protective effect of Atriplex halimus extract against benzene-induced haematotoxicity in rats [DOI]
  23. 23 Trace Elements and Free Radicals in Oxidative Diseases [DOI]
  24. 24 Evaluation of Algerian spontaneous species: phytochemical and biological study of aromatic and medicinal plant Marrubium vulgare
  25. 25 Biofungicide Activity of Datura stramonium Leaf Extract Against Phytopathogenic Fungi
  26. 26 Journal of Drug Delivery and Therapeutics [DOI]

Cited by 1

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