Pharmacological Activities of the Nelabevu/Bhunimba Aka Andrographis paniculata
Asian Journal of Research in Biochemistry · pp. 28–37 · Published 6 Sep 2023
10.9734/ajrb/2023/v13i2253Abstract
Andrographis paniculata, commonly known as Nelabevu, Bhunimba, Chirayetah, Kalmegh, or Creat, is a plant with extensive traditional use in Asian medicines. Its historical application, particularly in conditions related to blood irregularities, has driven contemporary scientific investigations into its therapeutic potential. This review summarizes the diverse aspects of Andrographis paniculata's traditional uses and modern applications, covering its effectiveness in respiratory infections, hepatoprotection, cardiovascular effects, antimicrobial and anti-inflammatory activities, hypoglycemic effects, and reproductive influences. The plant's active constituents, such as andrographolide, flavonoids, and diterpenoids, contribute to its pharmacological actions. However, critical evaluation and further research are essential to confirm its clinical benefits and mechanisms of action. The extensive range of its effects and the multiple active compounds highlight the plant's significance in modern herbal medicine and warrant continued exploration.
References (37)
- 1 Indigenous Drugs of India [DOI]
- 2 In vitro alpha-glucosidase and alpha-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide. [DOI]
- 3 In vitro screening of five local medicinal plants for antibacterial activity using disc diffusion method.
- 4 Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti‐inflammatory effect [DOI]
- 5 Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata [DOI]
- 6 Antimicrobial activity of Andrographis paniculata [DOI]
- 7 Antimalarial activity of extracts of Malaysian medicinal plants [DOI]
- 8 Antihyperglycemic Effect of Andrographolide in Streptozotocin-Induced Diabetic Rats [DOI]
- 9 In vitro and in vivo anti-inflammatory effects of andrographolide [DOI]
- 10 Antiangiogenic activity of Andrographis paniculata extract and andrographolide [DOI]
- 11 Suppression of Rat Neutrophil Reactive Oxygen Species Production and Adhesion by the Diterpenoid Lactone Andrographolide [DOI]
- 12 Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats [DOI]
- 13 Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin [DOI]
- 14 Inhibitory effect of andrographolide from Andrographis paniculata on PAF-induced platelet aggregation [DOI]
- 15 Andrographolide protects rat hepatocytes against paracetamol-induced damage [DOI]
- 16 Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice [DOI]
- 17 Materia Medica of India and Their Therapeutics
- 18 Anti-diabetic property of ethanolic extract of Andrographis paniculata in streptozotocin-diabetic rats.
- 19 Hepatoprotective Effect of Andrographolide Against Hexachlorocyclohexane-Induced Oxidative Injury [DOI]
- 20 HYPOTENSIVE ACTIVITY OF AQUEOUS EXTRACT OF ANDROGRAPHIS PANICULATA IN RATS [DOI]
- 21 Suppression of NO Production in Activated Macrophages in Vitro and ex Vivo by Neoandrographolide Isolated from Andrographis paniculata. [DOI]
- 22 Medicinal Plant Extracts as Anti–Escherichia coli O157:H7 Agents and Their Effects on Bacterial Cell Aggregation [DOI]
- 23 Andrographolide and kalmegh (Andrographis paniculata) extract: in vivo and in vitro effect on hepatic lipid peroxidation.
- 24 Evaluation of beneficial effects of antioxidant properties of aqueous leaf extract of Andrographis paniculata in STZ-induced diabetes.
- 25 Antioxidant action of Andrographis paniculata on lymphoma [DOI]
- 26 Antithrombotic effects of Andrographis paniculata nees in preventing myocardial infarction.
- 27 Inhibitory effects of neoandrographolide on nitric oxide and prostaglandin E2 production in LPS-stimulated murine macrophage [DOI]
- 28 Undetectable anti-bacterial activity of Andrographis paniculata (Burma) wall. ex ness.
- 29 The traditional plant, Andrographis paniculata (Sambiloto), exhibits insulin-releasing actions in vitro.
- 30 Antifertility effect of andrographis paniculata in mice.
- 31 Protective effects of Andrographis paniculata Nees on post-infarction myocardium in experimental dogs [DOI]
- 32 [Studies on diterpenoids from Andrographis paniculata].
- 33 Effect of Kalmegh extract on rat liver and serum enzymes.
- 34 Secondary Metabolites from Andrographis paniculata. [DOI]
- 35 Pharmacology and applications of chinese materia medica [DOI]
- 36 [Effects of Andrographis paniculata component on nitric oxide, endothelin and lipid peroxidation in experimental atherosclerotic rabbits].
- 37 [Studies on flavonoids of Andrographis paniculata].
Cited by 4
Priya M. Dandekar, Pooja V. Kotwal, Aslamkha C. Pathan · International Journal of Advanced Research in Science, Communication and Technology · 2024
Showing 1 of 4 known citations — external sources report more than can currently be individually listed.
Related research
- Antimicrobial Assessment of Annona muricata Fruits and Its Chemical Compositions — shares topic coverage
- Antimicrobial Activity, Phytochemical Screening and Nutrient Analysis of Tetrapleura tetraptera and Piper guineense — shares topic coverage
- Antifungal Susceptibility Pattern in Otomycosis among Patients Attending a Tertiary Healthcare Institution in Port Harcourt, Nigeria — shares topic coverage
- Evaluation of In-vitro Anti-Inflammatory, Anti-Fungal, Thrombolytic, Membrane Stabilizing and Cytotoxic Properties of (Camellia chrysantha Hu Tuyama) — shares topic coverage
- Design, Development, and Characterization of Luliconazole-loaded Bilosomal Gel for Enhanced Cutaneous Delivery — shares topic coverage
Article metrics
Real usage data collected on this platform.
90
Page views
0
PDF downloads
52
Outbound clicks
4
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.