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Research Article Open access CC BY 4.0

Overview on Sclerodermal Renal Crisis

Mahdi Ali M. Alyami, Jalawi Talal A. Alotaibi, Shahad Saad A. Aljoaid, Tariq Bander F. Alanazi, Waleed Farhan D. Alshammari, Nuwayr Hamdan D. Albalawi, Reema Abdulrahman A. Alanazi, Abrar Ali M. Aldhameen, Muflih Abdullah S. Albalawi, Mona Khalid M. Alqubali, Marawn Fahad H. Altemani, Abeer Abdulrhman. Basmih

Journal of Pharmaceutical Research International · pp. 88–95 · Published 12 Jul 2021

10.9734/jpri/2021/v33i36B31954

Abstract

Usually, malignant high blood pressure and severe renal damage are main characters in SSc. SRCs is a relatively rare condition, found in approximately 5% of all SSc patients. This study was carried out to summarize the contemporary evidence regarding the causes, risk factors, manifestations, management and prognosis of Sclerodermal Renal Crisis‎.‎ a simple review was carried out, searching databases PubMed, Google Scholar, and EBSCO. The authors extracted the needed data and stated that SRCs continues to be a rare diagnosis affecting up to six percent of SSc patients, but has a high morbidity and death influence. SRCs presentation is varied, with hypertension, normal BP and renal insufficiency. Medics should be minded by potential SRCs presentations. Early detection and initiation of aggressive ACEi antihypertensive medication in ED could enhance patient outcomes and around 60% of SRCs patients need dialysis.

Scleroderma systemic sclerosis renal crisis‎

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