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Research Article Open access CC BY 4.0

Overview on Post-Inflammatory Hyperpigmentation

Abdulrahman M. Albahlool, Omar Khalid M. Alshehri, Saeed Mohammed Alrasheed, Muzaynah Abdullah Al Ali, Abdullah Owaidh R. Al Sharif

Journal of Pharmaceutical Research International · pp. 393–399 · Published 29 Dec 2021

10.9734/jpri/2021/v33i63A35864

Abstract

Post inflammatory hyperpigmentation (PIH) can affect people of all skin colours, but it is more common in people of colour, such as African Americans, Hispanics/Latinos, Asians, Native Americans, Pacific Islanders, and those of Middle Eastern descent. There is no distinction between men and women. In darker-skinned acne sufferers, the prevalence of PIH might reach 65 percent. Many studies have demonstrated that topical retinoids, especially in darker skin types, can be beneficial in treating PIH associated with acne. However, Hydroquinone is still a go-to treatment for melasma and hyperpigmentation, and it's commonly referred to as the "gold standard." triple combination fixed treatment has also become a common intervention, with evidence showing that the combination is more successful than hydroquinone monotherapy. In this review article we will be looking at PIH etiology, epidemiology, different treatment options as well as the effectiveness of each medication.

Retinoid hyperpigmentation PIH hypermelanosis

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