Skip to content
Research Article Open access CC BY 4.0

Overview of Marker-assisted Selection in Animal Breeding

Prachi Sharma, Shilpa Doultani, K.K. Hadiya, LB George, HN Highland

Journal of Advances in Biology & Biotechnology · pp. 303–318 · Published 9 Apr 2024

10.9734/jabb/2024/v27i5790

Abstract

Marker-assisted selection (MAS) in animal breeding has undergone transformative advancements, reshaping genetic improvement and reproductive traits in livestock and expanding into new domains. From its inception in the late 20th century to current developments, MAS has evolved dynamically through the integration of genomic technologies, sophisticated statistical models, and innovative gene editing techniques. These advancements have significantly enhanced the precision and impact of MAS, revolutionizing genetic improvement and reproductive performance. By synergizing MAS with cutting-edge technologies, the collective aim is to optimize reproductive performance and genetic potential, fostering a sustainable and productive future for livestock breeding and beyond. The genetic markers, typically DNA sequences or genes linked to specific traits, revolutionized animal breeding by enabling the identification of animals carrying favorable genetic variants without the need for resource-intensive phenotypic evaluations. Marker-assisted selection in reproduction also laid the foundation for genomic selection, an advanced approach utilizing genome-wide markers to estimate breeding values and predict genetic potential. This comprehensive review encapsulates the journey of MAS, emphasizing its historical significance, current advancements, and promising future trajectories, showcasing its pivotal role in shaping the landscape of animal breeding and reproductive science.

Marker-assisted selection livestock breeding DNA markers QTL

References (92)

  1. 1 Fingerprinting genomes using PCR with arbitrary primers [DOI]
  2. 2 Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. [DOI]
  3. 3 High density synthetic oligonucleotide arrays [DOI]
  4. 4 The New Genomics: Global Views of Biology [DOI]
  5. 5 A review on SNP and other types of molecular markers and their use in animal genetics [DOI]
  6. 6 A Common Language for Physical Mapping of the Human Genome [DOI]
  7. 7 Microsatellites and their application to population genetic studies [DOI]
  8. 8 Diversity Arrays Technology (DArT) for whole-genome profiling of barley [DOI]
  9. 9 A genetic linkage map of the bovine genome [DOI]
  10. 10 Marker-assisted selection : current status and future perspectives in crops, livestock, forestry and fish
  11. 11 A genome-wide association study of meat and carcass traits in Australian cattle1 [DOI]
  12. 12 DNA marker technology: a revolution in animal genetics [DOI]
  13. 13 The Sensitivity of Single-Strand Conformation Polymorphism Analysis for the Detection of Single Base Substitutions [DOI]
  14. 14 Genetic diversity in Swiss goat breeds based on microsatellite analysis [DOI]
  15. 15 Microsatellite evolution--a reciprocal study of repeat lengths at homologous loci in cattle and sheep [DOI]
  16. 16 From the evolutionary past. . . [DOI]
  17. 17 Genome evolution: Are microsatellites really simple sequences? [DOI]
  18. 18 Marker assisted selection ‐ an overview [DOI]
  19. 19 Identification of Single Nucleotide Polymorphisms and analysis of Linkage Disequilibrium in sunflower elite inbred lines using the candidate gene approach [DOI]
  20. 20 Genetic diversity in nine native Turkish sheep breeds based on microsatellite analysis [DOI]
  21. 21 SNPs genotyping technologies and their applications in farm animals breeding programs: review [DOI]
  22. 22 Improvements to Bead-Based Oligonucleotide Ligation SNP Genotyping Assays [DOI]
  23. 23 RAPD Analysis of DNA Polymorphism in Turkish Sheep Breeds [DOI]
  24. 24 Detection of single base substitutions in total genomic DNA [DOI]
  25. 25 Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations [DOI]
  26. 26 PCR amplification of specific alleles (PASA) is a general method for rapidly detecting known single-base changes.
  27. 27 DNA fingerprints applied to gene introgression in breeding programs. [DOI]
  28. 28 The use of microsatellite analysis in population biology: Background, methods and potential applications [DOI]
  29. 29 Melting Curve Analysis of SNPs (McSNP ® ): A Gel-Free and Inexpensive Approach for SNP Genotyping [DOI]
  30. 30 Detection of species-specific genetic markers in farm animals through random amplified polymorphic DNA (RAPD) [DOI]
  31. 31 Use of AFLP Markers for Gene Mapping and QTL Detection in the Rat [DOI]
  32. 32 Genetic structure of Tsigai, Ruda, Pramenka and other local sheep in Southern and Eastern Europe [DOI]
  33. 33 Satellite DNA polymorphisms and AFLP correlate with Bos indicus-taurus hybridization [DOI]
  34. 34 Estimation of inbreeding in cattle using RAPD markers [DOI]
  35. 35 In Silico RAPD Priming Sites in Expressed Sequences and iSCAR Markers for Oil Palm [DOI]
  36. 36 Genetic structure of candidate genes for litter size in Italian Large White pigs [DOI]
  37. 37 Haplotype combination of the bovine CFL2 gene sequence variants and association with growth traits in Qinchuan cattle [DOI]
  38. 38 Limitations in the use of SSCP analysis [DOI]
  39. 39 Functional genes mapped on the chicken genome [DOI]
  40. 40 Genetic and Economic Responses for Within-Family Marker-Assisted Selection in Dairy Cattle Breeding Schemes [DOI]
  41. 41 Mapping the chicken genome [DOI]
  42. 42 Species identification in meat origin farm animals through DNA technology [DOI]
  43. 43 Characterization and polymorphism screening of IGF-I and prolactin genes in Nelore heifers [DOI]
  44. 44 Sequence‐tagged microsatellite sites as markers in chicken reference and resource populations [DOI]
  45. 45 Identification of clusters of biallelic polymorphic sequence-tagged sites (pSTSs) that generate highly informative and automatable markers for genetic linkage mapping [DOI]
  46. 46 Conserved sequence-tagged sites: a phylogenetic approach to genome mapping. [DOI]
  47. 47 Mapping Functional Chicken Genes: An Alternative Approach [DOI]
  48. 48 Microsatellites in Different Eukaryotic Genomes: Survey and Analysis [DOI]
  49. 49 PCR-SSCP: a simple and sensitive method for detection of mutations in the genomic DNA. [DOI]
  50. 50 Physical Mapping of Temperature-sensitive Mutations of Adenoviruses [DOI]
  51. 51 DNA polymorphisms amplified by arbitrary primers are useful as genetic markers [DOI]
  52. 52 AFLP: a new technique for DNA fingerprinting [DOI]
  53. 53 Diversity Arrays: a solid state technology for sequence information independent genotyping [DOI]
  54. 54 The evolution of molecular markers — just a matter of fashion? [DOI]
  55. 55 Recent advancements in molecular marker-assisted selection and applications in plant breeding programmes [DOI]
  56. 56 A 100-Year Review: Identification and genetic selection of economically important traits in dairy cattle [DOI]
  57. 57 Basic concepts and methodologies of DNA marker systems in plant molecular breeding [DOI]
  58. 58 Microsatellites and other simple sequences: genomic context and mutational mechanisms [DOI]
  59. 59 Molecular markers and their use in animal breeding [DOI]
  60. 60 Review on the development of genotyping methods for assessing farm animal diversity [DOI]
  61. 61 Genome-wide association analysis reveals genetic loci and candidate genes for feeding behavior and eating efficiency in Duroc boars [DOI]
  62. 62 Random Amplified Polymorphic DNA (RAPD) and Derived Techniques [DOI]
  63. 63 Genetic relationships and population structure in three Italian Merino-derived sheep breeds [DOI]
  64. 64 An STS-Based Map of the Human Genome [DOI]
  65. 65 The use of marker haplotypes in animal breeding schemes [DOI]
  66. 66 Microsatellite evolution in congeneric mammals: domestic and bighorn sheep. [DOI]
  67. 67 Accuracy of pedigree and genomic predictions of carcass and novel meat quality traits in multi-breed sheep data assessed by cross-validation [DOI]
  68. 68 The use of marker-assisted selection in animal breeding and biotechnology.
  69. 69 Morphological and microsatellite DNA diversity of Nigerian indigenous sheep [DOI]
  70. 70 Genetic Diversity of Kıvırcık Sheep Breed Reared in Different Regions and its Relationship with Other Sheep Breeds in Turkey [DOI]
  71. 71 Genetic markers for improving farm animals [DOI]
  72. 72 Differentiation of European cattle by AFLP fingerprinting [DOI]
  73. 73 Molecular identification of bamboo genera and species based on RAPD-RFLP markers [DOI]
  74. 74 Genetic features of Patanwadi, Marwari and Dumba sheep breeds (India) inferred by microsatellite markers [DOI]
  75. 75 Molecular Marker-Assisted Selection of ABCG2, CD44, SPP1 Genes Contribute to Milk Production Traits of Chinese Holstein [DOI]
  76. 76 Genetic Diversity Analysis Using Lowly Polymorphic Dominant Markers: The Example of AFLP in Pigs [DOI]
  77. 77 Use of DNA markers in animal selection [DOI]
  78. 78 Genetic variability among sheep breeds by random amplified polymorphic DNA-PCR
  79. 79 Marker-Assisted Selection [DOI]
  80. 80 Mapping of quantitative trait loci for reproductive traits in pigs [DOI]
  81. 81 Simultaneous detection of multiple single-base alleles at a polymorphic site.
  82. 82 A novel random amplified polymorphic DNA-based strategy for genetic diversity analysis and identification of tomatoes [DOI]
  83. 83 Genetic characterization of three fertility genes in Egyptian sheep and goat breeds [DOI]
  84. 84 A Comparison of Old and Modern Type DNA Marker Technologies and Their Impact on Animal Breeding Programs [DOI]
  85. 85 Koruma Altındaki Çine Çaparı Koyunlarda Genetik Çeşitliliğin Mikrosatellit İşaretleyiciler İle Analizi [DOI]
  86. 86 A Two-Stage Method for Improving the Prediction Accuracy of Complex Traits by Incorporating Genotype by Environment Interactions inBrassica napus [DOI]
  87. 87 Effects of Somatotropic Axis Gene Polymorphisms on Milk Yields in Simmental Cattle [DOI]
  88. 88 Some methods for analysing genetic marker data in a biodiversity setting - Example of PigBioDiv data.
  89. 89 Genetic and genomic approaches to improving sheep meat quality [DOI]
  90. 90 Journal of Dairy Science [DOI]
  91. 91 Reading Bits of Genetic Information: Methods for Single-Nucleotide Polymorphism Analysis [DOI]
  92. 92 Editorial: Genetic markers identification for animal production and disease resistance [DOI]

Cited by 75

Opportunities and Challenges of CRISPR-Cas9 in the Sustainable Development of Animal Husbandry

Jie Liu, Guanghang Feng, Conghui Guo · Journal of Agricultural and Food Chemistry · 2025

Invited review: Multiomics insights into the molecular and regulatory mechanisms underlying bovine mastitis

Eveline M. Ibeagha-Awemu, Mengqi Wang, Xin Zhao · Journal of Dairy Science · 2025

Advances in artificial intelligence for plant biology and crop breeding: An overview

Abdellatif Boutagayout, Rachid Ezzouggari, Mohamed Kouighat · AI Technologies for Crop Breeding · 2026

Molecular Regulation of Growth in Aquaculture: From Genes to Sustainable Production

Dana Andreea Șerban, Cristian-Alin Barbacariu, Mihaela Ivancia · Life · 2025

Identification of IGFBP2 gene polymorphism and association of genotypes with performance traits in Large White Yorkshire pigs

Rohit Solanki, S. S. Dhaka, Poonam Ratwan · Tropical Animal Health and Production · 2025

Enhancing rabbit farming efficiency with integrated genomics and nutritional strategies

Naqash Goswami, Ifeanyi Solomon Ahamba, Lionel Kinkpe · Frontiers in Animal Science · 2025

Molecular markers associated with growth, meat, and carcass traits in sheep: a review

Ainagul Begenova, Roman Bissengaliyev, Talgat Kulmagambetov · Animal Biotechnology · 2025

Exploring genetic variability and its association with growth traits in Rohilkhandi goats

Nitish Gaitri, Subodh Kumar, Pushpendra Kumar · Tropical Animal Health and Production · 2026

Showing 20 of 75 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

87

Page views

0

PDF downloads

24

Outbound clicks

75

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.