Screening of Some Commonly Used Medicinal Plants against Enteric Human Pathogen Vibrio cholerae

Abstract

Aim: Present study aims to screen some of the commonly used medicinal plants (Mangifera indica, Moringa oleifera, Pisidium guajava, Murraya koenigii and Ficus infectoria) and determination of minimum inhibitory concentration (MIC) against enteric human pathogen Vibrio cholera. Place and Duration of Study: Department of Zoology, Ranchi University, Ranchi, between January 2014-July 2014. Methodology: Plant extraction, antibacterial analysis and phytochemical analysis were Done. Results: The different methanolic leaf extracts differed in their vibriocidal properties. The MIC values of the plant extracts against test bacteria were in the range of 2-4 mg/mL by a disc diffusion method. P. guajava and F. infectoria showed promising vibriocidal property at 4 mg/mL concentration. Whereas the other three plants did not show any activity at the highest concentration. Broth dilution method showed 100% inhibition for all the extracts in the range 4-32 mg/mL.  Conclusion: All the extracts showed positive vibriocidal activity but P. guajava and F. infectoria showed promising activity and probably can be used as a safe medicine in diarrhea.