One Pot Synthesis of Tetra-substituted Imidazole Derivatives by Condensation Reaction Using Zeolite H- ZSM 22 as a Heterogeneous Solid Acid Catalyst

Abstract

The present work deals with the synthesis of tetra substituted imidazoles using environmentally benign and green catalyst H-ZSM-22. The synthesized catalyst was characterized by FTIR (Fourier-transform infrared spectroscopy), XRD and the products by FTIR and 1HNMR. H-ZSM-22 has been used as an efficient catalyst for an improved and rapid synthesis of 1,2,4,5 tetra substituted imidazoles derivatives using reactants: Benzil, Aldehydes, Amines and Ammonium acetate having excellent yield under solvent conditions. Different derivatives of aldehyde have been used in this reaction. For all the synthesized derivatives, ambient reaction time was found to be of 15-30 min. The main advantage of this reaction is small reaction time, high purity yield, easy work up and pollution free.