Comparative Phytochemical, Proximate and In vitro Antihyperglycemic Analyses of the Stem Bark Extracts of Kigelia africana (Lam.) Benth and Annona senegalensis Pers
C. E. Anarado, O. F. Obumselu, N. U. Ejimofor, N. P. Okafor, C. L. Igwe, J. C. Udekute, C. E. Igwe, C. B. Nsofor
Asian Journal of Chemical Sciences · pp. 40–48 · Published 16 Nov 2022
10.9734/ajocs/2022/v12i3222Abstract
The present research aimed to investigate the phytochemical bioactive constituents and proximate composition of the methanol extract of Kigelia africana and Annona senegalensis stem bark, as well as its in vitro antidiabetic potential. The results suggest that the presence of bioactive compounds may be responsible for the numerous medicinal capacities of these plants, including their antidiabetic abilities. The methanol stem bark extracts of K. africana and A. senegalensis demonstrated strong α-amylase and yeast cell glucose absorption inhibition, respectively. The stem bark methanol extract of A. senegalensis exhibited the highest level of inhibition (87.61%) at 0.1 mg/ml concentration when compared to conventional acarbose medication (56.0%) on the α-amylase enzyme. The percentage of glucose uptake by both methanol stem bark extract of Kigelia africana and Annona senegalensis was recorded maximum (31.40%) at a concentration of 0.5 mg/ml. The present research establishes the antidiabetic effect of methanol stem bark extract of Kigelia africana and Annona senegalensis by in vitro assays.
Cited by 0
No indexed citations yet.
Related research
- Antibacterial Activity of Bidens pilosa Extracts on Escherichia coli O157: H7 Isolated from Apparently Healthy Individuals — shares topic coverage
- Antimicrobial Activity, Phytochemical Screening and Nutrient Analysis of Tetrapleura tetraptera and Piper guineense — shares topic coverage
- Phytochemical and Nutraceutical Potentials of Beach Bean (Canavalia rosea SW.) DC Grown in Anyigba, Kogi State, Nigeria — shares topic coverage
- Phytochemical Screening, In vitro Antioxidant Capacity and Nephro-protective Effects of Combined Extract of Psidium guajava and Carica papaya Leaves in Rats Intoxicated with Cadmium — shares topic coverage
- Therapeutic Potential of Phytochemicals in Autoimmune Diseases: A Systematic Review — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.