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Research Article Open access CC BY 4.0

New Ray of Hope in Prognosis-Significance of Clinical, Histopathological and Biological Characteristics among Potentially Malignant Disorders and Oral Cancer– Case Series

G. Sathees Chandramouli, Ch. Uma Reddy, A. Steffina Lydia Jascinth, M. Anitha, B. R. Sathvikalakshmi

International Journal of Medical and Pharmaceutical Case Reports · pp. 1–7 · Published 2 Apr 2018

10.9734/IJMPCR/2018/39111

Abstract

Early detection of disease progression remains a challenging task mainly due to the lack of adequate early predictive markers. It is necessary to consider the biological behaviour and underlined molecular events while selecting treatment modalities in order to get the better outcome of oral potentially malignant disorders (OPMD) and oral cancer. The aim of the study was to evaluate Cytokeratin (CK) and vimentin expression in pre and post-treatment status of Oral leukoplakia, Oral sub mucous fibrosis (OSMF), Oral squamous cell carcinoma (OSCC) using Immunohistochemistry (IHC). These markers serve as prognostic indicators.

Cytokeratins vimentin oral potentially malignant disorders.

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